Results 131 to 140 of about 18,744,545 (170)

Synaptic density changes following electroconvulsive therapy: A longitudinal pilot study with PET-MR 11C-UCB-J imaging in late-life depression

Brain Stimulation
Maarten Laroy, Thomas Vande Casteele, Margot Van Cauwenberge, Michel Koole, Patrick Dupont, Stefan Sunaert, Jan Van den Stock, Pascal Sienaert, Koen Van Laere, Mathieu Vandenbulcke, Louise Emsell, Filip Bouckaert   +11 more
doaj   +3 more sources

In Vivo Synaptic Density Imaging with ¹¹C-UCB-J Detects Treatment Effects of Saracatinib in a Mouse Model of Alzheimer Disease. [PDF]

J Nucl Med, 2019
Toyonaga T, Smith LM, Finnema SJ, Gallezot JD, Naganawa M, Bini J, Mulnix T, Cai Z, Ropchan J, Huang Y, Strittmatter SM, Carson RE.   +11 more
europepmc   +1 more source

A new phenylstannyl precursor for synthesizing [11C]UCB-J

A new phenylstannyl precursor for synthesizing [11C]UCB-J
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The relationship between motor recovery and synaptic density changes after ischemic stroke: Imaging study with 11C-UCB-J PET

Turkish Journal of Neurology
Taha Burak Ayaz, Murat Kürtüncü
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Mapping the Synaptome in Neurodegeneration: Emerging Clinical Applications of SV2A PET Imaging. [PDF]

Mol Diagn Ther
Filippi L, Nuvoli S, Spanu A, Palumbo B.
europepmc   +1 more source

Building an open infrastructure for molecular neuroimaging: Standards and tools from the OpenNeuroPET initiative. [PDF]

J Cereb Blood Flow Metab
Ganz M, Norgaard M, Pernet C, Matheson GJ, Galassi A, Ceballos E, Bilgel M, Eierud C, Gonzalez-Escamilla G, Wighton P, Markiewicz CJ, Hardcastle N, Buckholtz J, Blair R, Greve DN, Thomas AG, Poldrack RA, Calhoun V, Innis RB, Knudsen GM.   +19 more
europepmc   +1 more source

Effects of radiotherapy on synaptic density as assessed by [11C]UCB-J PET in the brains of patients with head and neck cancer

van der Weijden, Chris W.J., Buunk, A. M., Spikman, Jacoba M, Kramer, Miranda, Langendijk, J.A., van Zon-Meijer, Tineke, de Vries, Erik F., van der Hoorn, Anouk   +7 more
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Preclinical PET Studies of [11C]UCB-J Binding in Minipig Brain

Molecular Imaging and Biology, 2020
Purpose: Loss of neuronal synapse function is associated with a number of brain disorders. The [11C]UCB-J positron emission tomography (PET) tracer allows for in vivo examination of synaptic density, as it binds to synaptic vesicle glycoprotein 2A (SV2A) expressed in presynaptic terminals.
Betina Elfving, Aage Kristian Olsen Alstrup, Anne M. Landau   +2 more
exaly   +4 more sources

Principal component analysis of synaptic density measured with [11C]UCB-J PET in Alzheimer's disease

The American Journal of Geriatric Psychiatry, 2021
Introduction Synaptic loss has been cited as an early pathological event and major structural correlate of cognitive impairment in Alzheimer's disease (AD). However, this observation is based on limited neuropathological studies. Here, we examined the in vivo relationship between synaptic density and cognitive performance in early AD using [11C]UCB-J ...
Ryan O'Dell, Albert Higgins-Chen, Dhruva Gupta, Ming-Kai Chen, Mika Naganawa, Takuya Toyonaga, Yihuan Lu, Emmie Banks, Hugh Bartlett, Joanna Harris, Wenzhen Zhao, Nabeel Nabulsi, Brent Vander Wyk, Yiyun Huang, Amy Arnsten, Richard Carson, Christopher van Dyck, Adam Mecca   +17 more
openaire   +1 more source