Results 121 to 130 of about 18,744,545 (170)

Associations of age, sex and body mass index to brain [11C]-UCB-J PET in first episode psychosis patients and healthy controls

Psychotic disorders are a complex, multifactorial group of disorders that are caused by both genetic and environmental factors. Although the underlying biochemical mechanisms are poorly understood, disturbed neuronal connectivity and altered synaptic ...
Rimpiläinen, Salla
core  

Synaptic Density in Multiple Sclerosis: An In Vivo Study Using [¹¹C]UCB-J-PET Imaging. [PDF]

Neurol Neuroimmunol Neuroinflamm
Luoma A, Matilainen M, Tuisku JM, Aarnio R, Nikkilä T, Laaksonen S, Koivumäki M, Honkonen E, Nylund M, Wahlroos S, Solin O, Chen MK, Toyonaga T, Lehto J, Snellman A, Rinne JO, Airas LM.   +16 more
europepmc   +1 more source

Binding of the synaptic vesicle radiotracer [¹¹C]UCB-J is unchanged during functional brain activation using a visual stimulation task. [PDF]

J Cereb Blood Flow Metab, 2021
Smart K, Liu H, Matuskey D, Chen MK, Torres K, Nabulsi N, Labaree D, Ropchan J, Hillmer AT, Huang Y, Carson RE.   +10 more
europepmc   +1 more source

Validation of a Simplified Tissue-to-Reference Ratio Measurement Using SUVR to Assess Synaptic Density Alterations in Alzheimer Disease with [¹¹C]UCB-J PET. [PDF]

J Nucl Med
Young JJ, O'Dell RS, Naganawa M, Toyonaga T, Chen MK, Nabulsi NB, Huang Y, Cooper E, Miller A, Lam J, Bates K, Ruan A, Nelsen K, Salardini E, Carson RE, van Dyck CH, Mecca AP.   +16 more
europepmc   +1 more source

Assessment of cerebral drug occupancy in humans using a single PET-scan: A [¹¹C]UCB-J PET study. [PDF]

Eur J Nucl Med Mol Imaging
Marstrand-Joergensen MR, Laurell GL, Herrmann S, Nasser A, Johansen A, Lund A, Andersen TL, Knudsen GM, Pinborg LH.   +8 more
europepmc   +1 more source

Assessment of a white matter reference region for ¹¹C-UCB-J PET quantification. [PDF]

J Cereb Blood Flow Metab, 2020
Rossano S, Toyonaga T, Finnema SJ, Naganawa M, Lu Y, Nabulsi N, Ropchan J, De Bruyn S, Otoul C, Stockis A, Nicolas JM, Martin P, Mercier J, Huang Y, Maguire RP, Carson RE.   +15 more
europepmc   +1 more source

Validation and noninvasive kinetic modeling of [¹¹C]UCB-J PET imaging in mice. [PDF]

J Cereb Blood Flow Metab, 2020
Bertoglio D, Verhaeghe J, Miranda A, Kertesz I, Cybulska K, Korat Š, Wyffels L, Stroobants S, Mrzljak L, Dominguez C, Liu L, Skinbjerg M, Munoz-Sanjuan I, Staelens S.   +13 more
europepmc   +1 more source

Synaptic Loss in Primary Tauopathies Revealed by [¹¹ C]UCB-J Positron Emission Tomography. [PDF]

Mov Disord, 2020
Holland N, Jones PS, Savulich G, Wiggins JK, Hong YT, Fryer TD, Manavaki R, Sephton SM, Boros I, Malpetti M, Hezemans FH, Aigbirhio FI, Coles JP, O'Brien J, Rowe JB.   +14 more
europepmc   +1 more source

Automated radiosynthesis of [¹¹ C]UCB-J for imaging synaptic density by positron emission tomography. [PDF]

J Labelled Comp Radiopharm, 2020
Milicevic Sephton S, Miklovicz T, Russell JJ, Doke A, Li L, Boros I, Aigbirhio FI.   +6 more
europepmc   +1 more source

The regional pattern of age-related synaptic loss in the human brain differs from gray matter volume loss: in vivo PET measurement with [¹¹C]UCB-J. [PDF]

Eur J Nucl Med Mol Imaging
Toyonaga T, Khattar N, Wu Y, Lu Y, Naganawa M, Gallezot JD, Matuskey D, Mecca AP, Pittman B, Dias M, Nabulsi NB, Finnema SJ, Chen MK, Arnsten A, Radhakrishnan R, Skosnik PD, D'Souza DC, Esterlis I, Huang Y, van Dyck CH, Carson RE.   +20 more
europepmc   +1 more source