Results 71 to 80 of about 5,463 (222)
Radiosensitization of noradrenaline transporter-expressing tumour cells by proteasome inhibitors and the role of reactive oxygen species [PDF]
, 2013 Background The radiopharmaceutical 131I-metaiodobenzylguanidine (131I-MIBG) is used for the targeted radiotherapy of noradrenaline transporter (NAT)-expressing neuroblastoma.
Babich, J.W. +4 more
core +3 more sources
Autonomic dysfunction in Huntington’s disease: A 123I-MIBG study [PDF]
Journal of Nuclear Cardiology, 2022 Ng, Arnold C. T. +2 more
openaire +3 more sources
Companion Diagnostics in Clinical Therapy: Current Applications and Future Directions
MedComm, Volume 7, Issue 3, March 2026.Companion diagnostics use biomarker‐based assays to stratify patients for precision therapies, improving outcomes while reducing ineffective treatment and side effects. This review summarizes the evolution, regulatory landscape, clinical applications, and technological platforms of CDx, highlighting their role in biomarker‐driven precision therapy.
Yuesong Wu +9 more
wiley +1 more source
EJNMMI Research, 2021 Background Since three-dimensional segmentation of cardiac region in 123I-metaiodobenzylguanidine (MIBG) study has not been established, this study aimed to achieve organ segmentation using a convolutional neural network (CNN) with 123I-MIBG single ...
Shintaro Saito +5 more
doaj +1 more source
Radiotracers for SPECT imaging: Current scenario and future prospects [PDF]
, 2012 Single photon emission computed tomography (SPECT) has been the cornerstone of nuclear medicine and today it is widely used to detect molecular changes in cardiovascular, neurological and oncological diseases.
Adak, S. +5 more
core +1 more source
Cancer Science, Volume 117, Issue 3, Page 777-786, March 2026.The safety and antitumor activity of crizotinib at a dose of 165 mg/m2 BID were evaluated in 16 patients with ALK‐positive ALCL in Japan. The most common grade 3 or 4 adverse event was neutropenia. The steady‐state Cmax and AUCtau of crizotinib at 165 mg/m2 BID were higher than expected. The objective response rate was 72.7% (90% CI, 43.6%–92.1%) among
Tetsuya Mori +12 more
wiley +1 more source
Analysis of short-term blood pressure variability in pheochromocytoma/paraganglioma patients [PDF]
, 2019 Data on short-term blood pressure variability (BPV), which is a well-established cardiovascular prognostic tool, in pheochromocytoma and paraganglioma (PPGL) patients is still lack and conflicting.
Bisogni, V. +14 more
core +1 more source
123I-MIBG scintigraphy and 18F-FDG-PET imaging for diagnosing neuroblastoma [PDF]
Cochrane Database of Systematic Reviews, 2015 Neuroblastoma is an embryonic tumour of childhood that originates in the neural crest. It is the second most common extracranial malignant solid tumour of childhood.Neuroblastoma cells have the unique capacity to accumulate Iodine-123-metaiodobenzylguanidine (¹²³I-MIBG), which can be used for imaging the tumour.
Bleeker, Gitta +6 more
openaire +2 more sources
Cancer, Volume 132, Issue 2, 15 January 2026.Abstract Background Survival for patients with high‐risk neuroblastoma remains poor despite current‐era multimodality treatment that includes postconsolidation GD2‐directed immunotherapy. Given the promising responses in patients who receive dinutuximab‐based chemoimmunotherapy in the relapsed setting, the Children’s Oncology Group ANBL19P1 study ...
Ami V. Desai +13 more
wiley +1 more source
Phaeochromocytoma Associated to Von Recklinghausen Neurofibromatosis Type I: a Rare Clinical Case [PDF]
, 2011 Os feocromocitomas são neoplasias originárias das células cromafins da crista neural localizados, na sua grande maioria, na medula supra-renal, podendo também aparecer nos gânglios simpáticos (paragangliomas).
Jorge, V +4 more
core