SDPR–STK38 axis controls the proliferation–differentiation balance in alveolar type II cells
The present study identifies SDPR as a pivotal regulator orchestrating the balance between proliferation and differentiation in alveolar type II (AT2) cells. In SDPR+/+ cells, SDPR binds to and inhibits STK38 activity, thereby sustaining GSK‐3β signaling functionality to promote cyclin D1 degradation and maintain cell cycle homeostasis.
Jie Wang +6 more
wiley +1 more source
Comparative analysis of fecal microbial community diversity between Bactrian camels and Mongolian cattle based on 16S rRNA gene sequencing. [PDF]
Ma X +6 more
europepmc +1 more source
Establishment and characterization of mouse lymph node fibrosis models
The design of the entire paper. Schematic illustration of four strategies for establishing mouse lymph node (LN) fibrosis models. The study further compares their fibrotic remodeling patterns and immune alterations. Abstract Background Lymph node (LN) fibrosis occurs in a variety of pathological conditions, including HIV infection, obesity, cancer, and
Yaru Niu +8 more
wiley +1 more source
Predicting antifouling paint particle contamination based on 16S rRNA gene sequencing data using random forest-based machine learning. [PDF]
Sperlea T +4 more
europepmc +1 more source
Patient‐Derived Fibroblasts as a Clinically Relevant Model of Kearns–Sayre Syndrome
Objective Kearns–Sayre syndrome (KSS) is characterized by single large‐scale mitochondrial DNA deletions and by severe early‐onset clinical manifestations with neurological involvement. Reliable disease models, as well as validated biomarkers or effective treatments, are lacking.
Laura Valls‐Roca +24 more
wiley +1 more source
16S rRNA Gene Amplicon Sequencing and Functional Profiling of Rhizosphere Bacteria in Date Palms Reveal Diverse Potential Plant Growth-Promoting Traits. [PDF]
Alsharif SM +3 more
europepmc +1 more source
Clade B carbon monoxide dehydrogenases (CODHs) remain enigmatic, diverging from canonical CODHs in structure and function. Here, we present the first characterization of Ruminococcus flavefaciens CODH (RfCODH), revealing occluded substrate pathways and attenuated CO oxidation activity.
Maximilian Böhm +6 more
wiley +1 more source
Detection and Genetic Diversity of Heritable Bacterial Symbionts in Human Lice Based on 16S-rRNA Gene. [PDF]
Marteau A, Brun S, Izri A, Akhoundi M.
europepmc +1 more source
This study aimed to investigate the potential of a mannan‐rich fraction (MRF) as a dietary intervention to alleviate weaning stress in piglets. Our results revealed that MRF could alleviate weaning stress by modulating the gut microbiota and the TLR5/NF‐κB signaling pathway, offering a novel and sustainable alternative to antibiotic use in swine ...
Yutong Lu +8 more
wiley +1 more source
16S rRNA gene V4 amplicon sequence data from <i>Acropora pulchra</i> tissue microbiome samples from Madura Island, Indonesia. [PDF]
Alina DN +4 more
europepmc +1 more source

