Results 91 to 100 of about 71,224 (157)

17β-Estradiol enhances neuronal differentiation of mouse embryonic stem cells [PDF]

, 2004
Existing protocols show a variety in the percentage of neurons that can be generated from mouse embryonic stem (ES) cells. In the current study, we compared effects of various differentiating conditions, including gelatin and poly-l-ornithine/fibronectin
Tatko, Lisa M, Pak, Elena S, Alexander K Murashov, Elena S Pak, Lisa M Tatko, Murashov, Alexander K, Hendricks, Wesley A, Wesley A Hendricks   +7 more
core   +1 more source

Gonadal Development–Related Genes and a Male‐Specific Genetic Marker Identified in the Endangered Sichuan Taimen (Hucho bleekeri)

Integrative Zoology, EarlyView.
Integrated transcriptomic and proteomic analyses were used to validate gonadal development–related genes and to identify a sex‐specific molecular marker in Hucho bleekeri. ABSTRACT Sex determination and differentiation represent fundamental topics in reproductive biology. Sichuan taimen (Hucho bleekeri), a first‐class national protected fish species in
Qinyao Wei, Hua Li, Yeyu Chen, Huanchao Yang, Jun Du, Zhaobin Song   +5 more
wiley   +1 more source

Order of magnitude differences between methods for maintaining physiological 17β-estradiol concentrations in ovariectomized rats

, 2008
The use of animal, especially rat, models, is crucial for elucidating the biological effects and mechanisms of the widely used hormone 17β-estradiol. Unfortunately there is a lack of consensus on optimal means of obtaining and maintaining physiological ...
Theodorsson, Annette,, Ström, Jakob O., Theodorsson, Elvar, Theodorsson, Elvar,, Ström, Jakob O.,, Theodorsson, Annette   +5 more
core   +1 more source

Feminizing Therapy in People With Klinefelter Syndrome and Gender Incongruence: Considerations for Treatment Without Testosterone Blockers

Andrology, EarlyView.
ABSTRACT Background Klinefelter syndrome (KS; 47, XXY) usually involves male sex development and gender identity. Small studies suggest gender incongruence may be more common in KS, but feminizing gender‑affirming hormone therapy in this group has been scarcely reported.
Maaike Kroon, Tamira Klaziene Klooker, Sabine Elisabeth Hannema, Martin Den Heijer   +3 more
wiley   +1 more source

Effects of dietary supplementation with 17β-estradiol on the Steroid Hormone Levels, Gonadosomatic Index, and Gonadal Histology of Female Silver Pompano (Trachinotus blochii) Broodstock

Depik Jurnal
Silver pompano (Trachinotus blochii) is a mariculture commodity with fast growth characteristics and easy adaptation to the environment. However, the production of its seeds is hindered by the maturation of the parent's gonads out-side the spawning ...
Azizah Azizah, Munti Sarida, Yudha Trinoegraha Adiputra, Gregorius Nugroho Susanto, Agus Setyawan   +4 more
doaj   +1 more source

Current Approaches to Support Patients to Withdraw From Image and Performance Enhancing Drugs

Clinical Endocrinology, EarlyView.
ABSTRACT Image and performance‐enhancing drugs (IPEDs) include agents such as androgens, growth hormone, and erythropoietin, which are used to enhance appearance and physical performance. Androgens, also known as anabolic‐androgenic steroids (AAS), are the most used IPEDs worldwide.
Elizabeth Hyams, Bonnie Grant, Richard Quinton, Channa N. Jayasena   +3 more
wiley   +1 more source

17β-Estradiol hyperpolarizes the membrane potential of freshly-isolated UBSM cells.

, 2015
A) A representative trace of a membrane potential recording in current-clamp mode (I = 0) demonstrating the hyperpolarizing effects of 17β-estradiol (100 nM) in an isolated UBSM cell. The hyperpolarizing effect of 17β-estradiol (100 nM) was reversed by 1
Shankar P. Parajuli (431005), Kiril L. Hristov (431003), Aaron Provence (822186), Georgi V. Petkov (431008)   +3 more
core   +1 more source

Borylcyclopropanes: Synthetic Strategies and Applications

Angewandte Chemie, Volume 138, Issue 37, 7 September 2026.
Borylcyclopropanes (cyclopropanes bearing a boron substituent) sit at the intersection of two privileged frameworks in synthesis. This review provides the first exhaustive survey of their chemistry, spanning metal–carbene, nucleophilic cyclization, radical, hydroboration, and C─H activation routes, and documenting applications in medicinal chemistry ...
Aiza A. Butt, Joseph M. Ready
wiley   +2 more sources

Physiological media and oxygen levels modulate cancer hallmarks in cultured breast cancer cells

The FEBS Journal, EarlyView.
MCF7 breast cancer cells were cultured in standard conditions (18% O2 and DMEM) and physiological conditions (5% O2 and Plasmax, a medium modeled after the human plasma metabolome). A combined transcriptomic and proteomic approach was used to identify gene expression signatures at the mRNA and protein levels upstream of functional enrichment analyses ...
Jacob E. Wiebe, Ricardo Alva, Fereshteh Moradi, Sarah Alderman, Ping Liang, Jeffrey A. Stuart   +5 more
wiley   +1 more source

G-Protein Coupled Estrogen Receptor (hGPER)- Mediated Action of 17β-Estradiol on hTREK-1 Potassium Channel [PDF]

, 2017
TREK-1 is a two-pore domain potassium channel that contributes to maintenance of the resting membrane potential of a cell. TREK-1 is involved in several physiological and pathophysiological conditions like nociception, anaesthesia, epilepsy, ischemia and
Choudhury, Nasreen
core