Results 31 to 40 of about 71,224 (157)

17β-Estradiol Regulates SKP2 Expression in Cultured Immature Boar Sertoli Cells Mainly via Estrogen Receptor β, cAMP-PKA and ERK1/2

Journal of Integrative Agriculture, 2014
Estrogen plays an important role in regulating testicular Sertoli cell number. Furthermore, S-phase kinase-associated protein 2 (SKP2) plays a central role in mammalian cell cycle progression.
Xian-zhong WANG, Feng-wei ZHU, Yong WANG, Yi WANG, Jiao-jiao ZHANG, Jia-hua ZHANG   +5 more
doaj   +1 more source

17β-Estradiol Inhibits Proliferation and Oxidative Stress in Vascular Smooth Muscle Cells by Upregulating BHLHE40 Expression

Frontiers in Cardiovascular Medicine, 2021
Background: Intimal hyperplasia is a major complication of restenosis after angioplasty. The abnormal proliferation and oxidative stress of vascular smooth muscle cells (VSMCs) are the basic pathological feature of neointimal hyperplasia.
Dan-dan Feng, Bin Zheng, Jing Yu, Jing Yu, Man-li Zhang, Man-li Zhang, Ying Ma, Ying Ma, Xiao Hao, Jin-kun Wen, Xin-hua Zhang   +10 more
doaj   +1 more source

17β-Estradiol enhances sulforaphane cardioprotection against oxidative stress [PDF]

, 2017
The lower incidence of ischemic heart disease in female with respect to male gender suggests the possibility that female sex hormones could have specific effects in cardiovascular protection.
ANGELONI, Cristina, Falconi, M, HRELIA, SILVANA, Malaguti, M, Hrelia, S., MALAGUTI, MARCO, Teti, G, Barbalace, Mc, BARBALACE, MARIA CRISTINA, FALCONI, MIRELLA, Angeloni, C, TETI, GABRIELLA   +11 more
core   +1 more source

Effects of 17β-estradiol and equilin on atherosclerosis development in female Apoe shl mice

Scientific Reports
The effects of conjugated equine estrogens (CEE) and 17β-estradiol-based hormone replacement therapy (HRT) on atherosclerosis development remain controversial.
Akiyo Kakibuchi, Fumitake Ito, Osamu Takaoka, Nanami Tahara, Mari Kawamata, Kazuya Yabumoto, Akihisa Katayama, Yuko Izumi, Eiko Maeda, Taisuke Mori   +9 more
doaj   +1 more source

Spatially Organized Human Ovarian Spheroids Instruct Endometrial Morphogenesis

Advanced Science, EarlyView.
A spatially organized human follicle‐like spheroid (SPHEGaT) composed of granulosa cells (GCs) and stromal‐derived theca‐like cells (TLCs) establishes sustained steroidogenesis in vitro. When co‐cultured with human endometrial organoids (EMOs), estradiol (E2) and progesterone (P4) exchange induces secretory/progesterone‐responsive differentiation ...
Maria João Sousa, Silke De Vriendt, Lixian Liu, Thalles Fernando Rocha Ruiz, Hugo Vankelecom, Christiani Andrade Amorim   +5 more
wiley   +1 more source

17β-estradiol modulates cardioprotective effects of nutraceutical compounds [PDF]

, 2018
Cardiovascular disease rarely manifests in pre-menopausal women meanwhile, the incidence of these pathologies dramatically increases after the menopause suggesting the possibility that sex hormones could have a key role.
Barbalace, Maria Cristina <1988>
core   +1 more source

17β-Estradiol Promotes Apoptosis of HepG2 Cells Caused by Oxidative Stress by Increasing Foxo3a Phosphorylation

Frontiers in Pharmacology, 2021
Liver cancer is associated with high mortality, particularly in patients infected with the hepatitis B virus. Treatment methods remain very limited. Here, we explored the effects of 17β-estradiol (E2) on apoptosis of various liver cell lines (LO2, HepG2,
Yusheng Guo, Yusheng Guo, Xiangsheng Cai, Xiangsheng Cai, Hanwei Lu, Qiqi Li, Ying Zheng, Zefang Lin, Zexiong Cheng, Maoxiang Yang, Li Zhang, Lei Xiang, Lei Xiang, Xiaorong Yang, Xiaorong Yang   +14 more
doaj   +1 more source

Magnetic Water Cleaning of Estrogens via Tight yet Dynamic Binding to Nanoparticles

Advanced Science, EarlyView.
Micropollution is one of the big challenges humanity faces with estrogen hormones being emerging pollutants of concern. Here, a supramolecular design strategy is presented that generates a simple nano‐adsorbent material to magnetically remove low‐concentrated estrogens from water.
Lukas Müller, Philip Maier, Dustin Vivod, Wenke Müller, Nikolaj Lopatik, Theresa Maria Schichtl, Julia Fröhlich, Irene Kraus, Marten Huck, Wieland Corts, Clodomiro Cafolla, Lukas Ruhm, Henrik Gaß, Johannes Voß, Jiwon Byun, Linda Rockmann, Guido Grundmeier, Kislon Voïtchovsky, Hans‐Georg Steinrück, Erdmann Spiecker, Sevim Dalabasmaz, Monika Pischetsrieder, Eike Brunner, Ralf Schweins, Dirk Zahn, Marcus Halik   +25 more
wiley   +1 more source

ZBTB18 Dysfunction Promotes Neuropathic Pain via CHD4‐based Epigenetic Disinhibition of CLIC1 Channels in Sensory Neurons

Advanced Science, EarlyView.
In this study, we identify a novel functional role of ZBTB18 in regulating trigeminal‐mediated neuropathic pain. Nerve injury reduces ZBTB18 in trigeminal ganglion neurons, impairing CHD4/NuRD recruitment and de‐repressing Clic1. Elevated CLIC1 enhances chloride channel activity and neuronal hyperexcitability, thereby driving pain.
Shoupeng Wang, Zitong Huang, Yu Tao, Yunmei Zhang, Yufang Sun, Dongsheng Jiang, Weiwei Lu, Fuhai Ji, Gang Chen, Min Xu, Yuan Zhang, Jin Tao   +11 more
wiley   +1 more source

The effect of 17β-estradiol administration on cutaneous wound healing in 24-week ovariectomized female mice [PDF]

, 2014
Estrogen replacement promotes cutaneous wound healing in 8–10-week young ovariectomized female mice. However, research using aged ovariectomized female mice has not been reported, to the best of our knowledge. Therefore, we investigated the effect of 17β-
Nakajima, Yukari, 22558, 22514, 22559, Nakatani, Toshio, 中島, 由加里, 22554, Urai, Tamae, Sugama, Junko, 向井, 加奈恵, 22555, 22556, 77295, 22557, Komatsu, Emi, Mukai, Kanae, 須釜, 淳子, 00203307, 60198124, Miyasaka, Yuriko, 40846680, 30755335, 32, 22526, 72008, Nasruddin, 1150, 223, 中谷, 壽男, 40252704, 20808670, Takata, Kana   +31 more
core   +2 more sources