Design and synthesis of 1,3,4-oxadiazole-tethered <i>N</i>-substituted isatin hybrids as SARS-CoV-2 main protease inhibitors: biological evaluation, kinetic investigation, and <i>in silico</i> studies. [PDF]
Al-Warhi T +10 more
europepmc +1 more source
Platelet‐Rich Fibrins as Local Drug‐Delivery Carriers
Autologous platelet concentrates (APCs), particularly platelet‐rich fibrin (PRF), act as biologically active fibrin scaffolds, capable of entrapping and gradually releasing therapeutic agents in oral and periodontal therapy. The incorporation of bioactive compounds, such as antibiotics, antifungals, vitamins, antidiabetic drugs, and exosomes, enhances ...
Karim M. Fawzy El‐Sayed +1 more
wiley +1 more source
Design, synthesis, molecular modelling and biological evaluation of oxiconazole-based 1,2,3-triazoles as dually acting antifungal and antitumor agents. [PDF]
Ismail AE +5 more
europepmc +1 more source
A MYB‐Related Transcriptional Module Cooperatively Represses Xylem Development in Poplar
ABSTRACT MYB transcription factors play crucial roles in regulating plant growth and development, but the functions of the MYB‐related subfamily in woody plants remain poorly understood. In this study, we characterized PagMYBR028, an MYB‐related transcription factor from poplar ‘84 K’ (Populus alba × Populus glandulosa), which was predominantly ...
Gaofeng Fan +8 more
wiley +1 more source
A Regioselective Approach to Accessing Trisubstituted Pyrrolo[2,3-d][1,2,3]triazoles via an Orthogonal Protection Strategy. [PDF]
Brugemann K +4 more
europepmc +1 more source
ABSTRACT Iron (Fe) homeostasis is regulated to prevent iron imbalance, with the help of redundant basic helix‐loop‐helix (bHLH) IVc transcription factors that can be controlled by Fe‐binding E3 ligases such as BRUTUS (BTS) in Arabidopsis thaliana.
Dibin Baby +5 more
wiley +1 more source
Oxadiazolone-Triazole Derivatives as a New Scaffold for Modulation of Angiotensin II-Induced Vascular Contraction. [PDF]
Ferreira LFL +5 more
europepmc +1 more source
ABSTRACT Soybean [Glycine max (L.) Merr.] is a globally important source of protein and edible oil, but is severely threatened by soybean mosaic virus (SMV). Wild soybean [Glycine soja Sieb. & Zucc.], the wild ancestor of cultivated soybean, exhibits high genetic diversity and strong resistance to pathogens.
Yixiang Pu +16 more
wiley +1 more source
Exploring the Antitubercular, Antimicrobial Potency, ADME-T Calculations and Docking Studies of 1,2,4-Triazole-Bearing Benzimidazoles. [PDF]
Shaik KM +4 more
europepmc +1 more source
Design, Synthesis, and Evaluation of New 1,4-Naphthoquinone-1,2,3-triazoles as Antimalarial Agents. [PDF]
Rezainia L +13 more
europepmc +1 more source

