Rapid Communications in Mass Spectrometry, EarlyView.ABSTRACT Rationale To increase the confidentiality level of molecular tags, binary information can be hidden in sequence‐defined oligomers using isobaric monomers including a photo‐sensitive one, which mass can be modified upon light irradiation. Reading such secured data requires light edition prior to MS/MS sequencing, which was investigated here in ...
Clothilde Comby‐Zerbino +3 more
wiley +1 more source
Triazole-Linked Pyrimidine Nucleoside Dimers: Design, Synthesis, and Applications in Medicinal and Nucleic Acid Chemistry. Part IV. [PDF]
Chem Biol Drug DesBaraniak D, Wawrzyniak D, Baranowski D.
europepmc +1 more source
Cooperative Regulation of Defect‐Mediated Molecular Recognition With Single‐Walled Carbon Nanotubes
Small, EarlyView.Defect‐mediated sensing in SWCNTs arises from the cooperative interplay of defect characteristics, density, heterogeneity, analyte properties, corona composition, and environment. Understanding these interconnected variables enables tunable fluorescence modulation, selective molecular recognition, ratiometric sensing, and sensitive detection in complex
Srestha Basu, Gili Bisker
wiley +1 more source
Unravelling recent advances in 1,2,4-triazole-based anticancer agents: synthetic strategies, molecular targets, molecular docking studies, and structure-activity relationships. [PDF]
RSC AdvMartis GJ +3 more
europepmc +1 more source
Advances in Unconventional and Sustainable Synthetic Approaches to Benzopyran Scaffolds
The Chemical Record, EarlyView.This review provides a comprehensive and critical analysis of low‐impact synthetic methodologies reported in the last 8 years (2018–2026) for the construction of benzopyran‐derived scaffolds, such as coumarins, flavones, chromones, chromenes, and chromanes. The benzopyran scaffold is a versatile family of heterocycles found in a wide range of bioactive
Nathalia B. Sá +4 more
wiley +1 more source
<i>Averrhoa bilimbi</i> L. Juice: An efficient natural acid catalyst for the green synthesis of dihydropyrimidinone-1,2,3-triazole. [PDF]
MethodsXArdiansah B +6 more
europepmc +1 more source
The Chemical Record, EarlyView.Two decades of synthetic strategies for sulfur‐, selenium‐decorated coumarins are critically surveyed through 44 literature reports, with particular emphasis on derivatives functionalized at the C‐3 and C‐4 positions. This review reports the direct construction of the coumarin framework through cyclization processes and late‐stage functionalization of ...
Bruna R. Schneider +6 more
wiley +1 more source
Beyond monofunctionality: structural perspectives on phenol oxidase side activity in a catalase
Acta Crystallographica Section D, EarlyView.Structural and biochemical characterization of the extracellular fungal catalase ClCPO uncovers an unexpected phenol oxidase promiscuity. Crystal structures, substrate docking and electron‐transfer pathway analysis identify ligand‐binding regions and support a working mechanistic model for catalase‐associated phenol oxidase activity.Catalases are ...
Christina Ferousi +5 more
wiley +1 more source
Genetic diversity and antifungal susceptibility among ecological niche populations of Aspergillus flavus in Yaoundé, Cameroon. [PDF]
PLoS OneKuate MPN +7 more
europepmc +1 more source
Covalent fluorescent probes for 2‐arachidonoylglycerol metabolic pathways
British Journal of Pharmacology, EarlyView.Abstract Covalent fluorescent probes have emerged as versatile chemical tools to visualise active enzymes in complex biological systems. When tailored for specific applications, ranging from activity‐based protein profiling for drug development to high spatiotemporal resolution imaging of enzymatic activities, these probes provide unique insights into ...
Nick D. F. Puijmbroeck +1 more
wiley +1 more source