Diversity and Multi-Target Potential of Pyrazole, Imidazole or Triazole Derivatives in Modern Anticancer Therapy. [PDF]
Mysłek M +3 more
europepmc +1 more source
Corrosion‐Protection of T122 Steel Using g‐C3N5‐Embedded Epoxy Coatings
Study evaluates g‐C3N5 (CN) reinforced epoxy coatings on T122 steel in NaCl and H2SO4. Electrochemical tests revealed that 2% loading maximizes corrosion resistance by blocking pores and limiting ion diffusion, increasing Rp and Rn. Optimized CN content enhances epoxy coating performance overall system durability material. ABSTRACT Corrosion‐protection
Martha Patricia Hernández‐Valencia +7 more
wiley +1 more source
Triazole-Functionalized Jatrophone Derivatives as Antiprotozoal Agents Against <i>Trypanosoma cruzi</i>: Synthesis, Biological Evaluation and Structure-Activity Relationships. [PDF]
Pertino MW +6 more
europepmc +1 more source
Hydroxamic Acids as HDAC Inhibitor Drug Leads for Malaria
ABSTRACT Malaria is a global health threat, with an estimated 282 million cases and 610,000 malaria‐associated deaths reported in 2024. Most mortality is due to infection by Plasmodium falciparum parasites, with the highest burden occurring in Sub‐Saharan Africa.
Wisam A. Dawood +7 more
wiley +1 more source
4-Sulfanyl-1,2,3-triazole as a Powerful Ligand in CuAAC to Synthesize 1,4-Substituted 1,2,3-Triazoles Under Solvent-Free and Low Catalyst Loading. [PDF]
Shen J +8 more
europepmc +1 more source
Advancing Therapies for Mycobacterial Diseases: From Small Molecules to Host‐Directed Strategies
ABSTRACT The global burden of multidrug‐resistant tuberculosis (MDR‐TB) and the rising incidence of nontuberculous mycobacterial (NTM) infections highlight the urgent need for innovative therapeutic strategies. Current treatments are prolonged, toxic, and increasingly compromised by resistance and limited diagnostic capacity.
Tânia Silva +23 more
wiley +1 more source
Biological and In Silico Evaluation of Novel Methoxyphenol-1,2,3-Triazole Hybrids as Multifunctional Anti-Alzheimer's and Anticancer Agents. [PDF]
Onur S, Çeşme M, Tümer F.
europepmc +1 more source
Boronic Acid Inhibitors of β‐Lactamases: A Promising Strategy Against Antimicrobial Resistance
ABSTRACT The rise of antimicrobial resistance (AMR) poses a critical threat to global health, mostly due to the proliferation of β‐lactamases, a class of enzymes responsible for the inactivation of β‐lactam antibiotics. Among the most promising strategies to restore β‐lactam efficacy is the use of β‐lactamase inhibitors (BLIs), with boronic acid ...
Nicolò Santi +4 more
wiley +1 more source
Solid-state structure and supra-molecular packing of 1,2-bis-(2-phenyl-1<i>H</i>-benzo[<i>d</i>]imidazol-1-yl)diazene. [PDF]
Constantinides CP, Yi JS, Marincean S.
europepmc +1 more source
Diverse reactivity of maleimides in polymer science and beyond
This mini‐review provides a thorough overview of maleimide chemistry, highlighting its diverse reactivity in polymer and materials science applications. Abstract Maleimides are remarkably versatile functional groups, capable of participating in homo‐ and copolymerizations, Diels–Alder and (photo)cycloadditions, Michael additions, and other reactions ...
Bruce E Kirkpatrick +2 more
wiley +1 more source

