Results 21 to 30 of about 5,282,956 (341)
1,2,4-Triazole derivatives are successfully used in medicine as antibacterial and antifungal agents. Aim of our research is the study of synthesis of 7'-((3-thio-4-ethyl-4H-1,2,4-triazole-5-yl)methyl)-3'-methylxanthine. Methods and results.
A. S. Gotsulya
doaj +1 more source
weak intermolecular interactions and catalytic ethylene oligomerisation [PDF]
The ligands 1-(cyclohexyl)-4-(2-pyridyl)-1,2,3-triazole (1), 1-(2,6-diisopropylphenyl)-4-(2-pyridyl)-1,2,3-triazole (2), 1-(4-butoxyphenyl)-4-(2-pyridyl)-1,2,3-triazole (3) and 1-(methyl)-4-(2-pyridyl)-1,2,3-triazole (4) were synthesized by the Cu(I ...
Braunstein, Pierre +4 more
core +1 more source
The creation of new biologically active compounds is a promising area of modern medicinal chemistry. Heterocyclic systems play an important role in this process.Among them, it is necessary to note 1,2,4-triazole and xanthine, the presence of which in the
K. D. Bakumovska, A. S. Hotsulia
doaj +1 more source
(E)-2-(4-Arylbut-1-en-3-yn-1-yl)chromones as synthons for the synthesis of xanthone-1,2,3-triazole dyads [PDF]
Xanthone-1,2,3-triazole dyads have been synthesized by two different approaches, both starting from novel (E)-2-(4-arylbut-1-en-3-yn-1-yl)chromones, prepared through a base-catalyzed aldol reaction of 2-methylchromone and arylpropargyl aldehydes.
Alexacou +39 more
core +1 more source
Analgesic activity of the salts of 2-(5-(adamantane-1-yl)-4-R-1,2,4-triazole-3-ylthio)acetic acid
Despite the varied approaches to the pain syndrome therapy with the changes and improvements of evolutionary medicine’s development and the drugs which are used to treat pain there are still considerable difficulties in solving this problem. Aim.
V. M. Odintsova
doaj +1 more source
Photochemistry of [Ru(pytz)(btz)2]2+and Characterization of a κ1-btz Ligand-Loss Intermediate [PDF]
We report the synthesis, characterisation and photochemical reactivity of the triazole-containing complex [Ru(pytz)(btz)2]2+ (1, pytz = 1-benzyl-4-(pyrid-2-yl)-1,2,3-triazole, btz = 1,1’-dibenzyl-4,4’-bi-1,2,3-triazolyl).
Amina Tariq +7 more
core +1 more source
The current market for antidepressants has a number of limitations, they have a high probability of development of adverse reactions, have low latitude and stability of the therapeutic effect, and also have a long latent period of action.
Ye. S. Pruhlo
doaj +1 more source
Synthetic, structural and biological studies of organosilicon(IV) complexes of Schiff bases derived from pyrrole-2-carboxaldehyde [PDF]
Selected new organosilicon(IV) complexes having the general formula R2SiCl[L] and R2Si[L] 2 were synthesized by the reactions of Me2SiCl2 with Schiff bases (5-mercapto-4-[(1H-pyrrol-2ylmethylene)amino]-s-triazole, 5-mercapto-3-methyl-4-[(1H-pyrrol ...
DHARAM PAL, KIRAN SING
core +1 more source
4-Amino-1,2,4-triazole-3-thione-derived Schiff bases as metallo-β-lactamase inhibitors.
Resistance to β-lactam antibiotics in Gram-negatives producing metallo-β-lactamases (MBLs) represents a major medical threat and there is an extremely urgent need to develop clinically useful inhibitors.
Laurent Gavara +26 more
semanticscholar +1 more source
A series of neat 4-(2-alkenyl) substituted 5-methyl-3-phenyl-4H-1,2,4-triazoles were thermolyzed at 320 oC producing a rearrangement products, of which the regioisomeric 1- and 2-substituted triazoles were the main products.
Per H.J. Carlsen +2 more
doaj +1 more source

