Results 21 to 30 of about 5,282,956 (341)

Synthesis and research on properties of 2-(4-еthyl-5-((3'-methylxantine-7'-yl)methyl)-4H-1,2,4-triazole-3-ylthio)acetic acid’s salts

open access: yesAktualʹnì Pitannâ Farmacevtičnoï ì Medičnoï Nauki ta Praktiki, 2016
1,2,4-Triazole derivatives are successfully used in medicine as antibacterial and antifungal agents. Aim of our research is the study of synthesis of 7'-((3-thio-4-ethyl-4H-1,2,4-triazole-5-yl)methyl)-3'-methylxanthine. Methods and results.
A. S. Gotsulya
doaj   +1 more source

weak intermolecular interactions and catalytic ethylene oligomerisation [PDF]

open access: yes, 2012
The ligands 1-(cyclohexyl)-4-(2-pyridyl)-1,2,3-triazole (1), 1-(2,6-diisopropylphenyl)-4-(2-pyridyl)-1,2,3-triazole (2), 1-(4-butoxyphenyl)-4-(2-pyridyl)-1,2,3-triazole (3) and 1-(methyl)-4-(2-pyridyl)-1,2,3-triazole (4) were synthesized by the Cu(I ...
Braunstein, Pierre   +4 more
core   +1 more source

Synthesis and properties of 7-((6-aryl-[1,2,4]triazolo[3,4-b][1,3,4]thiadiazol-3-yl)methyl)theophyllines

open access: yesФармацевтичний журнал, 2023
The creation of new biologically active compounds is a promising area of modern medicinal chemistry. Heterocyclic systems play an important role in this process.Among them, it is necessary to note 1,2,4-triazole and xanthine, the presence of which in the
K. D. Bakumovska, A. S. Hotsulia
doaj   +1 more source

(E)-2-(4-Arylbut-1-en-3-yn-1-yl)chromones as synthons for the synthesis of xanthone-1,2,3-triazole dyads [PDF]

open access: yes, 2015
Xanthone-1,2,3-triazole dyads have been synthesized by two different approaches, both starting from novel (E)-2-(4-arylbut-1-en-3-yn-1-yl)chromones, prepared through a base-catalyzed aldol reaction of 2-methylchromone and arylpropargyl aldehydes.
Alexacou   +39 more
core   +1 more source

Analgesic activity of the salts of 2-(5-(adamantane-1-yl)-4-R-1,2,4-triazole-3-ylthio)acetic acid

open access: yesAktualʹnì Pitannâ Farmacevtičnoï ì Medičnoï Nauki ta Praktiki, 2016
Despite the varied approaches to the pain syndrome therapy with the changes and improvements of evolutionary medicine’s development and the drugs which are used to treat pain there are still considerable difficulties in solving this problem. Aim.
V. M. Odintsova
doaj   +1 more source

Photochemistry of [Ru(pytz)(btz)2]2+and Characterization of a κ1-btz Ligand-Loss Intermediate [PDF]

open access: yes, 2016
We report the synthesis, characterisation and photochemical reactivity of the triazole-containing complex [Ru(pytz)(btz)2]2+ (1, pytz = 1-benzyl-4-(pyrid-2-yl)-1,2,3-triazole, btz = 1,1’-dibenzyl-4,4’-bi-1,2,3-triazolyl).
Amina Tariq   +7 more
core   +1 more source

Antidepressant activity of 4-amino-5-(alkyl-, aryl-, heteryl)-1,2,4-triazole-3-thione benzylidene derivatives

open access: yesAktualʹnì Pitannâ Farmacevtičnoï ì Medičnoï Nauki ta Praktiki, 2018
The current market for antidepressants has a number of limitations, they have a high probability of development of adverse reactions, have low latitude and stability of the therapeutic effect, and also have a long latent period of action.
Ye. S. Pruhlo
doaj   +1 more source

Synthetic, structural and biological studies of organosilicon(IV) complexes of Schiff bases derived from pyrrole-2-carboxaldehyde [PDF]

open access: yes, 2010
Selected new organosilicon(IV) complexes having the general formula R2SiCl[L] and R2Si[L] 2 were synthesized by the reactions of Me2SiCl2 with Schiff bases (5-mercapto-4-[(1H-pyrrol-2ylmethylene)amino]-s-triazole, 5-mercapto-3-methyl-4-[(1H-pyrrol ...
DHARAM PAL, KIRAN SING
core   +1 more source

4-Amino-1,2,4-triazole-3-thione-derived Schiff bases as metallo-β-lactamase inhibitors.

open access: yesEuropean journal of medicinal chemistry, 2020
Resistance to β-lactam antibiotics in Gram-negatives producing metallo-β-lactamases (MBLs) represents a major medical threat and there is an extremely urgent need to develop clinically useful inhibitors.
Laurent Gavara   +26 more
semanticscholar   +1 more source

Thermal Rearrangement of Allyl Substituted Unsymmetric 4H-1,2,4-Triazoles to the Corresponding 1H-1,2,4-triazoles

open access: yesMolecules, 2001
A series of neat 4-(2-alkenyl) substituted 5-methyl-3-phenyl-4H-1,2,4-triazoles were thermolyzed at 320 oC producing a rearrangement products, of which the regioisomeric 1- and 2-substituted triazoles were the main products.
Per H.J. Carlsen   +2 more
doaj   +1 more source

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