Results 31 to 40 of about 44,721 (246)
Biological activity of the derivatives of 1,2,4-triazole
Фармацевтичний журнал, 2018 The rapid development of modern medicine and pharmacy leads to an increase in synthetic drugs. Thus, in the professional literature says that one of the perspective directions are searching for new biologically active compounds including heterocyclic ...
T. V. Kravchenko +2 more
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ACUTE TOXICITYOF 4-AMINO-5-(2-, 3-, 4-NITROPHENYL)-1,2,4-TRIAZOLE-3-THIONES AND ITS DERIVATIVES
Aktualʹnì Pitannâ Farmacevtičnoï ì Medičnoï Nauki ta Praktiki, 2014 The aim of research. In recent years both domestic and foreign scientists pay great attention to the modeling of biologically active substances that can become the basis of new original drugs in future.
М. O. Shcherbak +2 more
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1-[2-(4-Bromobenzyloxy)-2-phenylethyl]-1H-1,2,4-triazole
Acta Crystallographica Section E, 2008 In the molecule of the title compound, C17H16BrN3O, the triazole ring is oriented at dihedral angles of 6.14 (9)° and 82.08 (9)°, respectively, with respect to the phenyl and bromobenzene rings.
Tuncer Hökelek +3 more
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Molecular docking, microwave-assisted synthesis, characterization, and preliminary evaluation of the anti-microbial activity of new sulfonamide derivatives of the 1, 2, 4-triazole-3-thiol ring system [PDF]
PharmaciaA new sulfonamide derivative containing a 1,2,4-Triazole-3-thiol ring was synthesized and characterized using FT-IR and 1H-NMR. The microwave-assisted chemical synthesis of the 1,2,4-Triazole-3-thiol ring system resulted in good yield and purity.
Ali Abdulhadi Mosleh, Zainab A. Dakhel
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Aktualʹnì Pitannâ Farmacevtičnoï ì Medičnoï Nauki ta Praktiki, 2018 Introduction. The nucleus of 1,2,4-triazole is the subject of close attention from a wide range of scientists because of numerous unique properties. Analyzing literary sources, it should be noted that there is a large amount of information devoted to the
D. M. Danilchenko
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Aktualʹnì Pitannâ Farmacevtičnoï ì Medičnoï Nauki ta Praktiki, 2015 Aim. To study the acute toxicity of 2-(5-(adamantane-1-yl)-4R-1,2,4-triazole-3-ylthio) acetic acids and their salts’ derivatives. Methods and results.
V. M. Odyntsova +2 more
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Aktualʹnì Pitannâ Farmacevtičnoï ì Medičnoï Nauki ta Praktiki, 2017 The nitrogen-containing heterocyclic systems from the class of 1,2,4-triazole derivatives, which exhibit wide range of actions, occupy special place among the variety of heterocyclic compounds.
V. M. Odyntsova
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Regarding antihypertensive tablets standardization
Aktualʹnì Pitannâ Farmacevtičnoï ì Medičnoï Nauki ta Praktiki, 2015 Hypertension is one of the most important problems of medicine related to its prevalence, late diagnosis and inefficient treatment. Antihypertensive treatment is the most effective way to prevent cardiovascular complications and reduce mortality.
N. V. Parnyuk
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Evaluation Of Antioxidant Activity Of 1, 2, 4-Triazole Derivatives With Morpholine Moiety
Hacettepe University Journal of the Faculty of Pharmacy, 2022 The aim of the work was to study the antioxidant activity of 4-R-3- (morpholinomethyl)-4H-1,2,4-triazole-5-thioles and their alkyl derivatives in vitro using the method of non-enzymatic initiation of lipid peroxidation. Among the 45 compounds studied, 8 showed varying degrees of AOA.
SHCHERBYNA, Roman +5 more
openaire +2 more sources
Yeast Gcn2 retains activity following humanization of its auto‐phosphorylation region
FEBS Open Bio, EarlyView.Using Saccharomyces cerevisiae as a model to study Gcn2 activation and regulation is limited by the lack of antibodies detecting phosphorylated Gcn2. To overcome this, we engineered Gcn2‐HsC, a yeast Gcn2 variant recognizable by commercial anti‐human phospho‐GCN2 antibodies.
Reuben A. Anderson +2 more
wiley +1 more source