Results 71 to 80 of about 46,711 (243)

Study acute toxicity of 4-(R-amino)-5-(thiophen-2-ylmethyl)-4H-1,2,4-triazole-3-thiol in vivo

Фармацевтичний журнал, 2018
Typically, the system is already known are used as the core for a new substance, which have already proved themselves as potential drugs. So one of these is 1,2,4-triazole ring.
A. A. Safonov
doaj   +1 more source

Self‐Assembled Pt(II) Complexes Boost Up Stem Cell Proliferation and Accelerate Metamorphosis in Living Organisms

Angewandte Chemie, EarlyView.
Pt1, an organometallic platinum‐based complex, act as a modulator of redox homeostasis in cnidarians, regulating cellular functions and life‐cycle dynamics. In Nematostella vectensis, it mitigates oxidative stress, strengthens detox systems and accelerates development.
Giuseppina Tommasini, Tania Pecoraro, Anna Lewinska, Maciej Wnuk, Olga Kolodziej, Daniela Intartaglia, Simona Morgera, Alessandro Aliprandi, Giulia Veronesi, Giorgio Facchetti, Isabella Rimoldi, Angela Tino, Claudia Tortiglione, Luisa De Cola   +13 more
wiley   +2 more sources

Aktivierung von Metallkomplexen durch Ultraschallwellen für eine gezielte Krebstherapie

Angewandte Chemie, EarlyView.
Ultrasound enables non‐invasive activation of metal‐based therapeutics deep within tumors. Acoustic cavitation can drive sonodynamic reactive oxygen species generation or mechanochemical metal–ligand bond dissociation, enabling controlled release of bioactive payloads.
Félix Grosjean, Nicolás Montesdeoca, Gilles Berger, Johannes Karges   +3 more
wiley   +1 more source

Synthesis of Large‐ and Medium‐Sized Heterobiaryl Atropisomeric Rings and Atropopeptides by Catalytic Intramolecular SNAr

Angewandte Chemie, EarlyView.
Catalytic, intramolecular N‐heterocycle arylation by nucleophilic aromatic substitution (SNAr) is now available for synthesis of highly strained macrocycles and medium‐sized heterobiaryl atropisomeric rings, including atropopeptides. Key to the approach is the ability to generate a strong base catalytically, taking advantage of base‐embedding ...
Alireza Abbasi Kejani, Paritosh Dey, Nicholas H. Stillman, Daniel M. Andrade, Michal Šimek, Martin Dračínský, Daniel Bím, Paulo H. S. Paioti   +7 more
wiley   +2 more sources

Current research trends of 1,2,4-triazole derivatives biological activity (literature review)

Aktualʹnì Pitannâ Farmacevtičnoï ì Medičnoï Nauki ta Praktiki
derivatives 1,2,4-triazole, biological activity,
I. M. Bilai , V. I. Dariy, A. V. Khilkovets, A. I. Bilai   +3 more
doaj   +1 more source

3D QSAR study on substituted 1, 2, 4 triazole derivatives as anticancer agents by kNN MFA approach. [PDF]

Saudi Pharm J, 2023
Desai SP, Mohite SK, Alobid S, Saralaya MG, Patil AS, Das K, Almadani ME, Arif Hussain S, Hussain Alamer B, Abdulrahman Jibreel E, Ibrahim Almoteer A, Mohammed Basheeruddin Asdaq S.   +11 more
europepmc   +1 more source

Synthesis of 3,5-di-(4-pyridyl)-1H-1,2,4-triazole

Molbank, 2008
n ...
Guang Yang, Li-Li Liu
doaj   +1 more source

The synthesis and highly effective antibacterial properties of Cu-3, 5-dimethy l-1, 2, 4-triazole metal organic frameworks. [PDF]

Front Chem, 2023
Xu X, Ding M, Liu K, Lv F, Miao Y, Liu Y, Gong Y, Huo Y, Li H.   +8 more
europepmc   +1 more source

An in vivo evaluation of anti-inflammatory, analgesic and anti-pyretic activities of newly synthesized 1, 2, 4 Triazole derivatives. [PDF]

BMC Complement Med Ther, 2021
Azim T, Wasim M, Akhtar MS, Akram I.
europepmc   +1 more source

Analgesic activity of 4-amino-5-methyl-4H-1,2,4-triazol-3-thiones

Aktualʹnì Pitannâ Farmacevtičnoï ì Medičnoï Nauki ta Praktiki, 2018
Аbstract Significance. Nowadays non-steroidal anti-inflammatory drugs have found a wide application in treatment of medical conditions. Despite the clinical effectiveness of non-steroidal anti-inflammatory drugs, their administration is followed by a ...
T. V. Kravchenko, О. I. Panasenko, Ye. G. Knysh   +2 more
doaj   +1 more source