Results 21 to 30 of about 97,768,553 (154)

In vitro competition with Bifidobacterium strains impairs potentially pathogenic growth of Clostridium perfringens on 2′-fucosyllactose [PDF]

Gut Microbes
Fortifying infant formula with human milk oligosaccharides, such as 2'-fucosyllactose (2'-FL), is a global trend. Previous studies have shown the inability of pathogenic gut microbes to utilize 2'-FL. However, the present study demonstrates that the type
Aruto Nakajima, Aleksandr A. Arzamasov, Mikiyasu Sakanaka, Ryuta Murakami, Tomoya Kozakai, Keisuke Yoshida, Toshihiko Katoh, Miriam N. Ojima, Junko Hirose, Saeko Nagao, Jin-Zhong Xiao, Toshitaka Odamaki, Dmitry A. Rodionov, Takane Katayama   +13 more
doaj   +2 more sources

Inulin-type fructans and 2’fucosyllactose alter both microbial composition and appear to alleviate stress-induced mood state in a working population compared to placebo (maltodextrin): the EFFICAD Trial, a randomized, controlled trial [PDF]

, 2023
There is increasing interest in the bi-directional relationship existing between the gut and brain and the effects of both oligofructose and 2'fucosyllactose to alter microbial composition and mood state.
Robert A. Rastall, Claire M. Williams, Jackson, Peter P. J., Rastall, Robert A., Jessica van Harsselaar, Stephan Theis, Peter PJ. Jackson, Williams, Claire M., Anisha Wijeyesekera, Wijeyesekera, Anisha, van Harsselaar, Jessica, Theis, Stephan   +11 more
core   +1 more source

Regulation of hBD-2, hBD-3, hCAP18/LL37, and Proinflammatory Cytokine Secretion by Human Milk Oligosaccharides in an Organotypic Oral Mucosal Model

Pathogens, 2021
Human milk oligosaccharides (HMOs), the third largest solid fraction in human milk, can modulate inflammation through Toll-like receptor signaling, but little is known about their immunomodulatory potential in the oral cavity.
Ulvi K. Gürsoy, Krista Salli, Eva Söderling, Mervi Gürsoy, Johanna Hirvonen, Arthur C. Ouwehand   +5 more
doaj   +1 more source

Safety of 2′‐fucosyllactose (2’‐FL) produced by a derivative strain (APC199) of Corynebacterium glutamicum ATCC 13032 as a novel food pursuant to Regulation (EU) 2015/2283 [PDF]

, 2022
Following a request from the European Commission, the EFSA Panel on Nutrition, Novel Foods and Food Allergens (NDA) was asked to deliver an opinion on 2′‐fucosyllactose (2’‐FL) as a novel food (NF) pursuant to Regulation (EU) 2015/2283.
Schlatter, Josef Rudolf, Tsabouri, S., Neuhäuser-Berthold, M., Castenmiller, Jacqueline, Prieto Maradona, Miguel, Schlatter, J. R., Maciuk, A., Poulsen, Morten, Pelaez, Carmen, Bohn, Torsten, Fernandez, Estefania Noriega, De Henauw, StefaanGE398010007602930000-0003-4141-5432F47B132E-F0ED-11E1-A9DE-61C894A0A6B4, de Henauw, S., Hirsch-Ernst, K. I., Naska, Androniki, Frenzel, T., Hirsch-Ernst, Karen Ildico, McArdle, Harry J., van Loveren, Henk, Thies, F., Noriega Fernández, Estefanía, Tsabouri, Sophia, Turck, Dominique, Siani, Alfonso, EFSA Panel on Nutrition, Novel Foods and Food Allergens (NDA), Naska, A., Noriega Fernández, E., Maradona, Miguel Prieto, Vinceti, Marco, Mangelsdorf, I., Nutr Novel Foods Food A, EFSA Panel, Vinceti, M., Cubadda, Francesco, Frenzel, Thomas, Prieto Maradona, M., Knutsen, Helle Katrine, Neuhäuser-Berthold, Monika, Pentieva, K., Knutsen, H. K., Cubadda, F., Pentieva, Kristina, Poulsen, M., McArdle, Harry J, Heinonen, Marina, van Loveren, H., Mangelsdorf, Inge, Thies, Frank, Pelaez, C., Colombo, Paolo, Mcardle, H. J., Marchelli, R., Neuhäuser‐Berthold, Monika, Maciuk, Alexandre, Bohn, T., Heinonen, M., Colombo, P., De Henauw, Stefaan, Marchelli, Rosangela, Hirsch‐Ernst, Karen Ildico, Siani, A., Castenmiller, J.   +60 more
core   +3 more sources

Effects of Different Human Milk Oligosaccharides on Growth of Bifidobacteria in Monoculture and Co-culture With Faecalibacterium prausnitzii

Frontiers in Microbiology, 2020
Human milk oligosaccharides (hMOs) are important bioactive components in mother’s milk contributing to infant health by supporting colonization and growth of gut microbes.
Lianghui Cheng, Mensiena B. G. Kiewiet, Madelon J. Logtenberg, Andre Groeneveld, Arjen Nauta, Henk A. Schols, Marthe T. C. Walvoort, Hermie J. M. Harmsen, Paul de Vos   +8 more
doaj   +1 more source

Selective proliferation of intestinal Barnesiella under fucosyllactose supplementation in mice [PDF]

, 2014
The oligosaccharides 2-fucosyllactose and 3-fucosyllactose are major constituents of human breast milk but are not found in mouse milk. Milk oligosaccharides have a prebiotic action, thus affecting the colonisation of the infant intestine by microbiota ...
Hennet, Thierry, Chassard, Christophe, Weiss, Gisela A, Weiss, Gisela A., Chassard C, Hennet T, Weiss GA   +6 more
core   +1 more source

The human milk oligosaccharide 2'-fucosyllactose alleviates liver steatosis, ER stress, and insulin resistance by reducing hepatic diacylglycerols and improving gut permeability in obese Ldlr-/-Leiden mice [PDF]

, 2022
Non-alcoholic fatty liver disease (NAFLD) is a complex multifactorial disorder that is associated with gut dysbiosis, enhanced gut permeability, adiposity and insulin resistance.
Attema, J., Heer, M., Kleemann, R., Ruiter, C. de, Bobeldijk-Pastorova, I., Gart, E., Caspers, M., Qin, Y., Salic, K., Giera, M., Morrison, M.C., Schuren, F.   +11 more
core   +1 more source

The Milk Active Ingredient, 2′-Fucosyllactose, Inhibits Inflammation and Promotes MUC2 Secretion in LS174T Goblet Cells In Vitro

Foods, 2023
In several mice inflammatory models, human milk oligosaccharides (HMOs) were shown to protect the intestinal barrier by promoting mucin secretion and suppressing inflammation. However, the functions of the individual HMOs in enhancing mucin expression in
Qianqian Yao, Huiying Li, Yanan Gao, Nan Zheng, Véronique Delcenserie, Jiaqi Wang   +5 more
doaj   +1 more source

2′-Fucosyllactose Ameliorates Oxidative Stress Damage in d-Galactose-Induced Aging Mice by Regulating Gut Microbiota and AMPK/SIRT1/FOXO1 Pathway

Foods, 2022
The imbalance of reactive oxygen species is the main cause in aging, accompanied by oxidative stress. As the most abundant in human milk oligosaccharides (HMOs), 2′-Fucosyllactose (2′-FL) has been confirmed to have great properties in immunity regulation
Jin Wang, Jia-Qiang Hu, Yu-Jie Song, Jia Yin, Yuan-Yi-Fei Wang, Bo Peng, Bo-Wei Zhang, Jing-Min Liu, Lu Dong, Shuo Wang   +9 more
doaj   +1 more source

Effects of human milk oligosaccharides (HMOs) on gastrointestinal health

Frontiers in Bioscience-Elite, 2020
Gastrointestinal (GI) health of newborns is maintained by the gastrointestinal microbiome, and the PNEI (psychoneuroendocrinoimmunology) system and can be altered by the delivery mode of the milk to the newborn such as breast versus bottle feeding ...
Maurizio Salamone, Veronica Di Nardo
doaj   +1 more source