Results 91 to 100 of about 97,768,553 (153)

Safety of 2’‐fucosyllactose/difucosyllactose mixture as a novel food pursuant to Regulation (EU) 2015/2283

EFSA Journal, 2019
Following a request from the European Commission, the EFSA Panel on Nutrition, Novel Foods and Food Allergens (NDA) was asked to deliver an opinion on 2’‐fucosyllactose/difucosyllactose (2’‐FL/DFL) mixture as a novel food (NF) pursuant to Regulation (EU)
EFSA Panel on Nutrition, Novel Foods and Food Allergens (NDA), Dominique Turck, Jacqueline Castenmiller, Stefaan De Henauw, Karen Ildico Hirsch‐Ernst, John Kearney, Alexandre Maciuk, Inge Mangelsdorf, Harry J McArdle, Androniki Naska, Carmen Pelaez, Kristina Pentieva, Alfonso Siani, Frank Thies, Sophia Tsabouri, Marco Vinceti, Francesco Cubadda, Karl Heinz Engel, Thomas Frenzel, Marina Heinonen, Rosangela Marchelli, Monika Neuhäuser‐Berthold, Annette Pöting, Morten Poulsen, Yolanda Sanz, Josef Rudolf Schlatter, Henk vanLoveren, Qingqing Sun, Emanuela Turla, Helle Katrine Knutsen   +29 more
doaj   +1 more source

Construction of an engineered Escherichia coli for effective synthesis of 2′-fucosyllactose via the salvage pathway

Synthetic and Systems Biotechnology
2′-Fucosyllactose (2′-FL) is one of the important functional oligosaccharides in breast milk. So far, few attempts on biosynthesis of 2′-FL by the salvage pathway have been reported.
Shanquan Liang, Zi He, Dan Liu, Shaoqing Yang, Qiaojuan Yan, Zhengqiang Jiang   +5 more
doaj   +1 more source

Structure-dependent degradation of milk oligosaccharides by newly isolated intestinal commensal bacterial strains from suckling piglets and rabbits

BMC Microbiology
Background Mammalian milk oligosaccharides serve as the first natural prebiotics for newborns, promoting the development of a beneficial gut microbiota. The ability of bacteria to use these complex sugars depends on their structure, but data are limited ...
Mathilde Rumeau, Sead Chadi, Frederic Pepke, Martin Beaumont, Cláudia M. Vicente, Agathe Juppeau, Céline Vandecasteele, Laurent Cauquil, Géraldine Pascal, Philippe Langella, Christelle Knudsen, Sylvie Combes, Rebeca Martín   +12 more
doaj   +1 more source

Human milk oligosaccharides regulate human macrophage polarization and activation in response to Staphylococcus aureus

Frontiers in Immunology
Human milk oligosaccharides (HMOs) are present in high numbers in milk of lactating women. They are beneficial to gut health and the habitant microbiota, but less is known about their effect on cells from the immune system. In this study, we investigated
Stine Dam Jepsen, Stine Dam Jepsen, Astrid Lund, Martin Matwiejuk, Lars Andresen, Kristine Rothaus Christensen, Søren Skov   +6 more
doaj   +1 more source

Air pollution exposure may impact the composition of human milk oligosaccharides

Scientific Reports
Human milk oligosaccharides (HMOs) impact neonate immunity and health outcomes. However, the environmental factors influencing HMO composition remain understudied. This study examined the associations between ambient air pollutant (AAP) exposure and HMOs
Noopur C. Naik, Elizabeth A. Holzhausen, Bridget N. Chalifour, Maria M. Coffman, Fredrick Lurmann, Michael I. Goran, Lars Bode, Tanya L. Alderete   +7 more
doaj   +1 more source

Early-life 2′-fucosyllactose and its combination with Bifidobacterium bifidum TMC3115: Sex-specific effects in learning, spatial memory, and hyperactivity in juvenile spontaneous hypertensive rats as an attention deficit/hyperactivity disorder model

Journal of Dairy Science
: This study investigated the preventive effects of early-life intervention with 2′-fucosyllactose (2′-FL) or synbiotic (2′-FL plus Bifidobacterium bifidum TMC3115) on newborn spontaneous hypertensive rats (SHR) as an attention deficit/hyperactivity ...
Yang Yang, Simou Wu, Jianxiu Liu, Yating Luo, Jinxing Li, Kai Wang, Fang He, Ruyue Cheng   +7 more
doaj   +1 more source

Abstracts From AIDS 2026, the 26th International AIDS Conference, 26 – 31 July 2026 Rio de Janeiro, Brazil & virtual

Journal of the International AIDS Society, Volume 29, Issue S4, July 2026.
wiley   +1 more source

Data_Sheet_1_Immunomodulatory and Prebiotic Effects of 2′-Fucosyllactose in Suckling Rats.PDF

, 2019
Human milk oligosaccharides are unconjugated complex glycans present in high concentration in human milk that serve as pre-biotics and immunomodulators.
Bernd Stahl (829556), M. José Rodríguez-Lagunas (7108010), Johan Garssen (278720), Belinda van't Land (7108007), Àngels Franch (3335625), Karen Knipping (343214), Ignasi Azagra-Boronat (7108001), Francisco J. Pérez-Cano (7108013), Jordi Mayneris-Perxachs (540587), Sebastian Tims (551851), Margarida Castell (3335622), Malén Massot-Cladera (7108004)   +11 more
core   +1 more source

Innovative direct introduction‐ion mobility–mass spectrometry (DI‐IM‐MS) approach for fast and robust isomer‐specific quantification in a complex matrix: Application to 2′‐fucosyllactose (2’‐FL) in breast milk

International audienceAbstract Identification and specific quantification of isomers in a complex biological matrix by mass spectrometry alone is not an easy task due to their identical chemical formula and therefore their same mass‐to‐charge ratio ( m/z
Paris, Alain, Alves, Sandra, Rathahao-Paris, Estelle, Guillon, Blanche, Fenaille, François, Abdoun, Sarah, Venot, Eric, Adel-Patient, Karine   +7 more
core   +1 more source

2’-Fucosyllactose modulates the function of intestinal microbiota to reduce intestinal permeability in mice colonized by feces from healthy infants

Food Science and Human Wellness
2’-Fucosyllactose (2’-FL) shows the potential to support intestinal health as a natural prebiotic that bridges the gap between infant formula feeding and breastfeeding.
Qingxue Chen, Liu Yang, Fangqin Xiang, Ignatius Man-Yau Szeto, Yalu Yan, Biao Liu, Jinju Cheng, Lu Liu, Bailiang Li, Sufang Duan   +9 more
doaj   +1 more source