Results 41 to 50 of about 97,768,097 (202)

PERBEDAAN RERATA KADAR 2-METHOXYESTRADIOL PADA EARLY ONSET PREEKLAMPSIA BERAT DENGAN LATE ONSET PREEKLAMPSIA BERAT [PDF]

, 2020
ABSTRAK Pendahuluan : Tingginya angka kematian ibu tersebut dianggap sebagai pertanda adanya masalah pada status kesehatan dan pelayanan kesehatan di suatu negara.
Jofril, Azmi
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2-Methoxyestradiol and Disorders of Female Reproductive Tissues

Hormones and Cancer, 2014
2-Methoxyestradiol (2ME) is an endogenous metabolite of 17β-estradiol. Once thought of as a mere degradation product, 2ME has gained attention as an important component of reproductive physiology and as a therapeutic agent in reproductive pathologies such as preeclampsia, endometriosis, infertility, and cancer.
Pinto, M., Medina, R., Owen, Gareth Ivor
openaire   +11 more sources

Supplementary Fig. S1 from Class I β-tubulin mutations in 2-methoxyestradiol-resistant acute lymphoblastic leukemia cells: implications for drug-target interactions

, 2008
Supplementary Fig. S1 from Class I β-tubulin mutations in 2-methoxyestradiol-resistant acute lymphoblastic leukemia cells: implications for drug-target ...
Matthew J. McKay (607279), Anne M. Cunningham (15036335), David E. Hibbs (183890), Maria Kavallaris (54201), Tracy Y.E. Liaw (15036332), Noeris K. Salam (221887)   +5 more
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Molecular crosstalk between apoptosis and autophagy induced by a 2-methoxyestradiol analogue (C19) in HeLa cells [PDF]

, 2012
Using a novel synthesised sulphamoylated 2-methoxyestradiol analogue, C19, two types of cell death, namely apoptosis and autophagy, were demonstrated in vitro when cervical cancer HeLa cells were exposed to this compound.http://www.satnt.ac ...
Prudent, Renaud, Stander, Andre, Joubert, Annie M., Visagie, M.H. (Michelle Helen), Theron, Anne Elisabeth, Lafanechere, Laurence, Mqoco, T.V. (Thandi Vuyelwa)   +6 more
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HIF-1α participates in secondary brain injury through regulating neuroinflammation

Translational Neuroscience, 2023
A deeper understanding of the underlying biological mechanisms of secondary brain injury induced by traumatic brain injury (TBI) will greatly advance the development of effective treatments for patients with TBI. Hypoxia-inducible factor-1 alpha (HIF-1α)
Xu Xiaojian, Yang Mengshi, Zhang Bin, Dong Jinqian, Zhuang Yuan, Ge Qianqian, Niu Fei, Liu Baiyun   +7 more
doaj   +1 more source

Supplementary Table S1 from Class I β-tubulin mutations in 2-methoxyestradiol-resistant acute lymphoblastic leukemia cells: implications for drug-target interactions

, 2008
Supplementary Table S1 from Class I β-tubulin mutations in 2-methoxyestradiol-resistant acute lymphoblastic leukemia cells: implications for drug-target ...
Matthew J. McKay (607279), Anne M. Cunningham (15036335), David E. Hibbs (183890), Maria Kavallaris (54201), Tracy Y.E. Liaw (15036332), Noeris K. Salam (221887)   +5 more
core   +1 more source

Supplementary Fig. S1 legend from Class I β-tubulin mutations in 2-methoxyestradiol-resistant acute lymphoblastic leukemia cells: implications for drug-target interactions

, 2008
Supplementary Fig. S1 legend from Class I β-tubulin mutations in 2-methoxyestradiol-resistant acute lymphoblastic leukemia cells: implications for drug-target ...
Matthew J. McKay (607279), Anne M. Cunningham (15036335), David E. Hibbs (183890), Maria Kavallaris (54201), Tracy Y.E. Liaw (15036332), Noeris K. Salam (221887)   +5 more
core   +1 more source

Development, Optimization and Evaluation of 2-Methoxy-Estradiol Loaded Nanocarrier for Prostate Cancer

Frontiers in Pharmacology, 2021
The therapeutic efficacy of antineoplastic agents possessing a selective target to the nucleus of the cancer cells could be enhanced through novel formulation approaches.
Nabil A. Alhakamy, Nabil A. Alhakamy, Nabil A. Alhakamy, Osama A. Ahmed, Osama A. Ahmed, Usama A. Fahmy, Usama A. Fahmy, Hani Z. Asfour, Adel F. Alghaith, Wael A. Mahdi, Sultan Alshehri, Shadab Md, Shadab Md   +12 more
doaj   +1 more source

Preparation and evaluation of 2-methoxyestradiol-loaded pH-sensitive liposomes

, 2019
The development and clinical application of 2-methoxyestradiol (2-ME) as a new type of antitumor drug are limited due to its poor solubility, rapid metabolism in vivo, and large oral dosage.
Qian Yang (300330), Bowen Wang (526637), Runfang Zhang (10650749), Huanhuan Zhou (5345819), Suna He (12848721)   +4 more
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2-Methoxyestradiol-bis-sulfamate induces apoptosis and autophagy in a tumorigenic breast epithelial cell line [PDF]

, 2011
In anticancer research where the focus is on finding agents that induces cell death while leaving nontumorigenic cells less affected, a novel 2-methoxyestradiol derivative has come forth.
Joubert, Annie M., Visagie, M.H. (Michelle Helen)   +1 more
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