Reactions of 2-methylchromones with cyanoacetamides and ethyl cyanoacetate. synthesis of 6-(2-hydroxyaryl)-4-methyl-2-oxo-1,2-dihydropyridine-3- carbonitriles and 7-hydroxy-6-imino-9-methyl-6h-benzo[c]chromene-8-carbonitriles [PDF]
, 2013 Although 2-methylchromones react with cyanoacetamide and N-methyl cyanoacetamide in the presence of sodium ethoxide in refluxing ethanol to produce 6-(2-hydroxyaryl)-4-methyl-2-oxo-1,2-dihydropyridine-3-carbonitriles, their reactions with ethyl ...
Al Naimi +23 more
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Angewandte Chemie, Volume 137, Issue 48, November 24, 2025.A practical, stereoselective method for synthesizing tri‐ and tetra‐substituted 1,2‐fluoro‐borylalkenes and alkynes via defluorinative C–C coupling of CF3–arenes with organodiboron reagents is reported. Enabled by a Lewis base activator, products are formed in up to 94% yield and >98:2 Z/E selectivity.
José L. Rosario‐Collazo +3 more
wiley +1 more source
Synthesis of 6-(2-hydroxyaryl)-2-pyridones by the reaction of chromones with cyanoacetic, acetoacetic, and malonic acid amides [PDF]
, 2013 A reaction of chromones with cyanoacetic, acetoacetic, and malonic acid amides in the presence of sodium ethoxide furnished a number of new 3-substituted 6-(2-hydroxyaryl)-2-pyridones in good yields, including those containing a polyfluoroalkyl group at ...
Anufriev, V. A. +2 more
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IUCrJ, 2016 A novel design strategy for cocrystals of a sulfonamide drug with pyridine carboxamides and cyclic amides is developed based on synthon identification as well as size and shape match of coformers.
Geetha Bolla, Ashwini Nangia
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Synthesis of 4,6-dimethyl-3-cyano-2-pyridone catalysed by amino acids
Zaštita Materijala, 2017 In this work the synthesis of 4,6-dimethyl-3-cyano-2-pyridone catalyzed by amino acids was studied. In the first part of the work, the optimization was carried out by varying the initial concentration of glycine, the molar ratio of the reactants ...
Nevena Ž. Prlainović +3 more
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Inhibition of DNA polymerase reactions by pyrimidine nucleotide analogues lacking the 2-keto group [PDF]
, 2017 To investigate the influence of the pyrimidine 2-keto group on selection of nucleotides for incorporation into DNA by polymerases, we have prepared two C nucleoside triphosphates that are analogues of dCTP and dTTP, namely 2-amino-5-(2′-deoxy-β-d ...
Guo, Mao-Jun +5 more
core
Chemistry Central Journal, 2012 Background A series of some novel arylazo pyridone dyes was synthesized from the corresponding diazonium salt and 6-hydroxy-4-phenyl-3-cyano-2-pyridone using a classical reaction for the synthesis of the azo compounds.
Alimmari Adel +7 more
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Antimicrobial activities of secondary metabolites of endophytic fungi isolated from Catharanthus roseus [PDF]
, 2017 Introduction: Recently, several endophytes have been shown to possess the potentials to synthesize novel bioactive compounds that have found use for drug discovery. We isolated endophytic fungi associated with Catharanthus roseus collected from the river
Abba, Chika C. +6 more
core +2 more sources
Synthesis of 6-Nitroderivatives of Oxazolo[3,2-a]-pyridines and Their Reactions with Nucleophiles
Molecules, 2003 5-Nitro-2-pyridone can be selectively N-phenacylated, and the resulting phenacylpyridones I undergo cyclization to 6-nitrooxazolo[3,2-a]pyridinium salts II.
Eugene V. Babaev, Alexander A. Bush
doaj +1 more source
Inertial axis reorientation in the S1←S electronic transition of 2-pyridone. A rotational Duschinsky effect. Structural and dynamical consequences [PDF]
, 1991 Andrew Held +2 more
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