Results 61 to 70 of about 21,673,697 (241)

Construction of Fully Substituted 2-Pyridone Derivatives via Four-Component Branched Domino Reaction Utilizing Microwave Irradiation.

Journal of Organic Chemistry, 2018
Microwave irradiation, four-component branched domino reaction of methyl acetoacetate/2,4-pentanedione, diethyl malonate, triethyl orthoformate and amines offering an extremely efficient strategy for the construction of fully substituted 2-pyridone ...
Hairui Bai, Rongrong Sun, Shitao Liu, Lijuan Yang, Xuebing Chen, Chao Huang   +5 more
semanticscholar   +1 more source

1-[(2-Chloro-7,8-dimethylquinolin-3-yl)methyl]pyridin-2(1H)-one

Acta Crystallographica Section E, 2010
In the title compound, C17H15ClN2O, the quinoline ring system is nearly planar, with a maximum deviation from the mean plane of 0.074 (2) Å, and makes a dihedral angle of 81.03 (7)° with the pyridone ring ...
F. Nawaz Khan, S. Mohana Roopan, Venkatesha R. Hathwar, Mehmet Akkurt   +3 more
doaj   +1 more source

Urinary metabolic profiles in early pregnancy are associated with preterm birth and fetal growth restriction in the Rhea mother-child cohort study [PDF]

, 2014
Syftet med studien var att undersöka vilka möjligheter matematikundervisning utomhus kan ge för elevernas utveckling och lärande. Syftet var även att undersöka hur utomhusmatematik kan användas som ett komplement till den traditionella ...
Maitre, L, Fthenou, E, Athersuch, T, Coen, M, Toledano, MB, Holmes, E, Kogevinas, M, Chatzi, L, Keun, HC   +8 more
core   +1 more source

Recyclable All‐in‐One Organo‐Photo‐Auxiliaries Enabling (sp3)C−(sp3)C Coupling Reactions with Diverse Functionalities

Advanced Synthesis &Catalysis, Volume 367, Issue 5, March 4, 2025.
Abstract Photochemical C−C coupling reactions can be tailored to industrial chemical processes and preparations of pharmaceuticals. Recent approaches in this area are limited to using precious transition metal coordination complexes that facilitate light absorption and redox processes with benchtop chemicals. Herein, we propose a paradigm that involves
Samjhana Maharjan, Ravi Kishore Dakoju, Bella Albano, Pamela A. Ondiek, Joseph M. O'Shea, Angel G. Cosme‐Hernandez, Donald Wink, Barry C. Pemberton, Steven A. Lopez, A. Jean‐Luc Ayitou   +9 more
wiley   +1 more source

Innovative solutions to sticky situations: Antiadhesive strategies for treating bacterial infections [PDF]

, 2016
Bacterial adherence to host tissue is an essential process in pathogenesis, necessary for invasion and colonization and often required for the efficient delivery of toxins and other bacterial effectors.
Aberg, Abgottspon, Allen, Allison, Alves, Aminov, Anderson, Andersson, Andersson, Andreini, Anthouard, Arnqvist, Aronson, Arrecubieta, Ashkar, Autar, Avorn, Bajolet-Laudinat, Barbosa-Cesnik, Barczak, Barnhart, Barnhart, Barocchi, Blanco, Bouckaert, Bouckaert, Boukerb, Boyle, Branderhorst, Breimer, Breimer, Briles, Britton, Brown, Buffie, Candela, Cecioni, Cecioni, Cegelski, Chabre, Chagnot, Chang, Chapman, Chemani, Chen, Chen, Chorell, Choudhury, Cioci, Clatworthy, Cole, Coppa, Cossart, Costerton, Cozens, Cusumano, Dam, Delnay, DePas, Dethlefsen, Diggle, Dodson, Donlan, Dramsi, Ebersbach, Eto, Evans, Fagon, Falugi, Ferreira, Findlow, Finlay, Finlay, Fischetti, Flores-Mireles, Foo, Ford, Foxman, Frankel, Furiga, Gao, Garcia-Medina, Gaudreau, Geibel, Gellatly, Ghosh, Giugliano, Glick, Goller, Gouin, Goyal, Greco, Greene, Griebling, Guiton, Guiton, Guiton, Guiton, Gustafsson, Guttilla, Haataja, Hakkarainen, Hammar, Hammer, Hammer, Hampton, Han, Han, Hansson, Hart, Haslam, Hauck, Hawley, Hentzer, Hernell, Hofmann, Hollenbeck, Horvath, Howell, Hung, Hung, Hur, Hur, Idanpaan-Heikkila, Isberg, Jacob-Dubuisson, Jay, Jiang, Jones, Jones, Joosten, Juliano, Kadam, Kadam, Kai-Larsen, Kang, Kang, Kauppi, Keeney, Kelly, Kierek-Pearson, Kim, Kim, Kim, Kisiela, Kleeb, Klein, Klein, Klein, Kline, Kontiokari, Konto-Ghiorghi, Korhonen, Kozel, Krachler, Krachler, Krachler, Kruger, Kummerfeldt, Langermann, Langermann, Lanne, Lanne, Larsson, Lebeaux, Lee, Lee, Lee, Lehner, Lewis, Li, Liu, Liukkonen, Lo, Loveless, Lund, Lyczak, Ma, Mack, Mamo, Mandlik, Manefield, Mapingire, Maresso, Maresso, Maresso, Marotte, Marraffini, Mayville, Mazmanian, Mazmanian, Menard, Migone, Migone, Miller, Mitchell, Morrow, Morvan, Munera, Murray, Mysore, Nallapareddy, Neeser, Nenninger, Nenninger, Newburg, Nicolle, Nielsen, Nielsen, Nielubowicz, Nishikawa, Nishikawa, Nishiyama, Nuccio, O'Toole, Ofek, Ofek, Oh, Oh, Oh, Ohlsson, Ohlsson, Okuda, Olsen, Oppong, Orndorff, Otsuka, Paganelli, Pak, Palumbi, Pang, Park, Parker, Patel, Perret, Pertici, Peychl, Phan, Piatek, Pieters, Pinkner, Prabu, Proft, Puorger, Pusztai, Raghunathan, Rapsinski, Rasko, Remaut, Remaut, Rivera, Roberts, Robinson, Rosen, Ruiz-Palacios, Saeki, Saldana, Salminen, Sauer, Sauer, Savar, Scharenberg, Schlager, Schneewind, Schroten, Schulte, Schwardt, Scott, Sekirov, Serruto, Sheth, Shu, Signoretto, Smith, Song, Staat, Stamm, Starkey, Steadman, Stromqvist, Su, Svensson, Thanassi, Therrien, Thomas, Tielker, Toivanen, Ton-That, Ton-That, Ton-That, Ton-That, Turgeon, Ubeda, Van Houdt, Vangay, Vengadesan, Volkan, Walsh, Wang, Wang, Wellens, Whittaker, Wilson, Wolinsky, Wu, Wu, Wurpel, Xiao, Yamaguti-Sasaki, Yamanaka, Yanagawa, Younson, Zhang, Zhang, Zinger-Yosovich   +314 more
core   +2 more sources

The Immune Microenvironment: New Therapeutic Implications in Organ Fibrosis

Advanced Science, EarlyView.
This review summarizes recent advances in understanding the immune microenvironment's role in fibrosis, focusing on phenotypic/functional alterations of immune cells and their dynamic interactions with other cellular constituents within tissues. The authors further explore therapeutic opportunities and challenges in targeting immune microenvironment ...
Xiangqi Chen, Chuan Wu, Fei Tang, Jingyue Zhou, Li Mo, Yanping Li, Jinhan He   +6 more
wiley   +1 more source

Nucleophile-Catalyzed Additions to Activated Triple Bonds. Protection of Lactams, Imides, and Nucleosides with MocVinyl and Related Groups [PDF]

, 2014
Additions of lactams, imides, (S)-4-benzyl-1,3-oxazolidin-2-one, 2-pyridone, pyrimidine-2,4-diones (AZT derivatives), or inosines to the electron-deficient triple bonds of methyl propynoate, tert-butyl propynoate, 3-butyn-2-one, N-propynoylmorpholine, or
Adler M., Aggarwal V. K., Alewi B. A., Alonso D. A., Ando K., Anna M. Costa, Ariza X., Baidya M., Balasubramaniam S., Barry C. S., Benohoud M., Bonache M.-C., Broch S., Chatterjee T., Chen H.-G., Costa A. M., Costa A. M., Dandepally S. R., David de Vicente, De Rycke N., Delamarche I., Denes F., Díez-González S., Esteban J., Faja M., Fan M.-J., Foettinger A., Goossen L. J., Goossen L. J., Gorka Etxebarría-Jardí, Hein J. E., Hosokawa T., Janey J. M., Jaume Vilarrasa, Jin S., Joan Font, Joaquim Caner, Kabir M. S., Katz E., Kurosu M., Laura Mola, Lee E., Lee E., Lewis A. F., Liao Y., Lin T. S., Liu Y., Lluís Bosch, Martín R., Matsuya Y., Mayr H., Mekkonen B., Nishimura T., Olivella A., Oriol Pineda, Peshakova L., Pursglove L. A., Ramazani A., Reisman S. E., Robinson R. S., Scheiner P., Seo J. H., Smith N. L., Spychala J., Tejedor D., Tejedor D., Trost B. M., Tyler P. C., Villa M. V. J., Wang J., Yavari I., Ylioja P. M.   +71 more
core   +2 more sources

Enantiopure Chiral Crystals: A Powerful Tool for Absolute Asymmetric Synthesis

Asian Journal of Organic Chemistry, EarlyView.
This review covers absolute asymmetric syntheses, which allow the preparation of enantiomerically enriched chiral compounds from achiral precursors. By exploiting the crystallization of certain compounds as a conglomerate, enantiopure chiral crystals are spontaneously obtained.
Jiacheng Li, Valérie Alezra
wiley   +1 more source

Synthesis of Multi‐Substituted β‐Carbolin‐1‐ones via Iridium‐Catalyzed Intramolecular C─H/N─H Amination of 3‐Amino‐2‐pyridones

Asian Journal of Organic Chemistry, EarlyView.
A method for the synthesis of multi‐substituted β‐carbolin‐1‐ones is developed, utilizing iridium‐catalyzed intramolecular C─H/N─H amination of 3‐amino‐2‐pyridones synthesized via the conjugate addition of diethyl 2‐aminomalonate to alkynyl imines.
Honoka Mori, Maho Morimura, Ayana Okada, Hiroyoshi Masuda, Iwao Hachiya   +4 more
wiley   +1 more source

2-Bromopyridines as Versatile Synthons for Heteroarylated 2-Pyridones via Ru(II)-Mediated Domino C–O/C–N/C–C Bond Formation Reactions

Molecules
A novel methodology for the synthesis of 2-pyridones bearing a 2-pyridyl group on nitrogen and carbon atoms, starting from 2-bromopyridines, was developed employing a simple Ru(II)–KOPiv–Na2CO3 catalytic system.
Miha Drev, Helena Brodnik, Uroš Grošelj, Franc Perdih, Jurij Svete, Bogdan Štefane, Franc Požgan   +6 more
doaj   +1 more source