Synthesis of 5-(substituted phenylazo)-6-hydroxy-4-methyl-3-cyano-2-pyridones from ethyl 3-oxo-2-(substituted phenylazo)butanoates, Short communication [PDF]
Journal of the Serbian Chemical Society, 2011 A new procedure for the synthesis of known azo pyridone dyes is presented. A series of 5-(substituted arylazo)-6-hydroxy-4-methyl-3-cyano-2-pyridones were prepared from ethyl 3-oxo-2-(substituted phenylazo)butanoates and cyanoacetamide in acetone using ...
GORDANA UŠĆUMLIĆ +3 more
doaj
Molecules, 2012 Pirfenidone, a pyridone compound, is an effective and novel antifibrotic agent. In this article, we describe the design, synthesis and activity evaluation of novel antifibrotic agents, 1-(substituted aryl)-5-trifluoromethyl-2(1H) pyridones modified with ...
Lijian Tao +9 more
doaj +1 more source
, 2017 The cationic gold phosphine complex [(P1)Au(NCMe)]+SbF6– [P1 = P(t-Bu)2o-biphenyl; 2] catalyzes the intramolecular hydroamination of 6-alkenyl-2-pyridones to form 1,6-carboannulated 2-pyridones in high yield.
Jacob C. Timmerman (3119301) +2 more
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Regioselective Halogenations and Subsequent Suzuki−Miyaura Coupling onto Bicyclic 2-Pyridones
, 2016 A selective synthesis of 6-bromo-8-iodo dihydro thiazolo ring-fused 2-pyridones is described. These halogenated 2-pyridones are selectively arylated by sequential Suzuki−Miyaura couplings.
Fredrik Almqvist (698391) +1 more
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SYNTHESIS AND ANTIINFLAMMATORY ACTIVITY OF SOME NOVEL THIENOPYRIMIDINE DERIVATIVES
Zagazig Journal of Pharmaceutical Sciences, 2004 4-Chloro-5,6,7,8-tetrahydrobenzothieno[2,3-d]pyrimidine (3) was reacted with 4-aminoacetophenone in ethanol to give 4(4- acetylanilino)5,6,7,8-tetrahydrobenzothieno[2,3-d]pyrimidine (4).
Zakaria Abd El-Samii +3 more
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Synthesis, properties and colour assessment of some new 5-(3- and 4-substituted phenylazo)-4,6-dimethyl-3-cyano-2-pyridones [PDF]
Journal of the Serbian Chemical Society, 2006 A series of 5-(3- and 4-substituted phenylazo)-4,6-dimethyl-3-cyano-2-pyridones were synthesized, starting from acetylacetone and arenediazonium salt, followed by condensation with cyanoacetamide using a modified literature procedure.
DUSAN MIJIN +5 more
doaj
An experimentally simple one-pot preparation of N-alkenyl-2-pyridones is reported. The reaction features mild conditions using readily available 2-halopyridinium salts and aldehydes. N-Alkenyl-2-pyridone formation proceeds with high diastereoselectivity,
Grant N. Shivers (11362506) +1 more
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Simple and Efficient Synthesis of 3,4-Dihydro-2-pyridones via Novel Solid-Supported Aza-Annulation
, 2016 A diverse array of 3,4-dihydro-2-pyridones 13 were produced utilizing the unique properties of solid-supported reactions to both drive the reactions to completion and isolate the desired products. The pyridones were synthesized in high purity by a simple
Liang Wang (23021) +2 more
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Synthesis and Cyclizations of N-(2,3-, 3,4- and 3,5-Dimethylphenyl)-β-alanines
Molecules, 2005 A series of 1-aryl substituted dihydro-, 5-methyldihydro- and 6-methyl-dihydro-2,4(1H,3H)pyrimidinediones and their 2-thio analogues were obtained byreaction of the corresponding β-alanines or α-methyl- and β-methyl-β-alanines with ureaor ...
Gema Mikulskiene +2 more
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Cytotoxic hexadepsipeptides and anti-coronaviral 4-hydroxy-2-pyridones from an endophytic Fusarium sp. [PDF]
Front Chem, 2022 Chang S +9 more
europepmc +1 more source