The reaction of acyclic enaminones with methoxymethylene Meldrum's acid afforded N-adduct and/or C-adduct of enaminones in moderate to good yields. The regiochemistry of this reaction depends on the N-amino substituent of the enaminone. The C-adduct is a
Cunha Silvio +4 more
doaj
An overview of synthesis and biological activities of 2-pyridone derivatives over the last decade
2-Pyridone frameworks are a pervasive member of the N-heterocyclic family of both chemical and therapeutic interest. 2-Pyridones and their bridged analogues have wide occurrences in nature and the presence of both aromatic and amide groups in the ...
Lopamudra Das, Tista Sengupta
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Design, Synthesis, and Antimicrobial Evaluation of a New Series of N-Sulfonamide 2-Pyridones as Dual Inhibitors of DHPS and DHFR Enzymes. [PDF]
Azzam RA, Elsayed RE, Elgemeie GH.
europepmc +1 more source
Synthesis of diphenylphosphoryl enamines, 2-pyridones and 2-pyrrolidones
Elvira Peláez Arango +3 more
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RhIII-Catalyzed Synthesis of Isoquinolones and 2-Pyridones via Annulation of N-Methoxyamides and Nitroalkenes. [PDF]
Potter TJ, Li Y, Ward MD, Ellman JA.
europepmc +1 more source
Anti-Parkinsonian 4-hydroxy-2-pyridones from an endolichenic fungus, Tolypocladium sp. (strain CNC14). [PDF]
Choi JW +5 more
europepmc +1 more source
A lesson for site-selective C-H functionalization on 2-pyridones: radical, organometallic, directing group and steric controls. [PDF]
Hirano K, Miura M.
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Concise Entries to 4-Halo-2-pyridones and 3-Bromo-4-halo-2-pyridones [PDF]
Timothy Gallagher, Aurélien Honraedt
openaire +1 more source
Efficient and divergent synthesis of polyfunctionalized 2-pyridones from β-keto amides. [PDF]
Gao B +6 more
europepmc +1 more source
Photoredox-Catalyzed Radical Coupling of C7-Chloromethyl-Substituted Thiazolino Ring-Fused 2-Pyridones with Quinoxalinones. [PDF]
Hellgren V +6 more
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