Results 71 to 80 of about 24,429,900 (206)
Drug Design, Development and Therapy, 2017 Galal Elgemeie,1 Farag Altalbawy,2,3 Mohammed Alfaidi,3 Rania Azab,2,4 Atef Hassan5 1Department of Chemistry, Faculty of Science, Helwan University, Helwan, 2National Institute of Laser Enhanced Sciences (NILES), Cairo University, Giza, Egypt ...
Elgemeie G +4 more
doaj
Dakin-West Trick in the Design of Novel 2-Alkyl(aralkyl) Derivatives of Oxazolo[3,2-a]pyridines
Molecules, 2005 A series of previously unavailable derivatives of 2-alkyl- and 2-benzylderivatives of oxazolo[3,2-a]pyridines III were obtained via tandem ring opening and ring closure from stable mesoionic 3-acyloxazolo[3,2-a]pyridinium-2-olates I.
Eugene V. Babaev +2 more
doaj +1 more source
ChemMedChem, Volume 21, Issue 16, 27 August 2026.Human immunodeficiency virus (HIV) allosteric integrase inhibitors (ALLINIs) offer a vital alternative to standard therapies by targeting noncatalytic sites. By inducing aberrant integrase multimerization, they disrupt viral maturation. This review explores their medicinal chemistry evolution, detailing structural insights, structure–activity ...
Francesco Saccoliti +10 more
wiley +1 more source
Synthèse et réactivité des 2-Pyridones [PDF]
, 2014 Nous avons pu mettre au point, au cours de ce travail, une nouvelle voie de synthèse des 2-Pyridones non décrites dans la littérature, cette stratégie est basée sur l’utilisation des composés dicarbonylés et des cyanoacétamides.
Attar, Sarah
core
Regioselective Halogenations and Subsequent Suzuki-Miyaura Coupling onto Bicyclic 2-Pyridones
, 2010 A selective synthesis of 6-bromo-8-iodo dihydro thiazolo ring-fused 2-pyridones is described. These halogenated 2-pyridones are selectively arylated by sequential Suzuki-Miyaura couplings.
Bengtsson, Christoffer, +1 more
core +1 more source
Study of Diels-Alder Reactions of 2-Pyridones Acting as Dienophile Using Molecular Orbital Method [PDF]
, 2003 Diels-Alder reactions of 4-substituted 2(1H)-pyridones with 2, 3-dimethyl-1, 3-butadiene were studied using ab initio molecular orbital method. Yields of adducts were roughly consistent with calculated activation energies.
コバヤシ, アケミ +11 more
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Photochemistry of Aromatic N‐Oxides in Water Probed by Time‐Resolved X‐ray Absorption Spectroscopy
Chemistry – A European Journal, Volume 32, Issue 29, 7 August 2026.Time‐resolved XAS at the nitrogen and oxygen K‐edges is applied to the photorearrangement of two N‐oxides in water. Pyridine N‐oxide rapidly forms the oxaziridine isomer. Pyridazine N‐oxide undergoes ring opening to the diazo compound, without any evidence of intermediates.
Maximilian Paradiz Domínguez +3 more
wiley +1 more source
Molecules, 2004 The reaction of 4-hydroxycoumarin (1) with some primary amines 2a-h and morpholine (2i) under microwave irradiation occurred without opening of the lactone ring to give N-substituted 4-aminocoumarins 3a-i in excellent yields.
Ivo C. Ivanov, Edmont V. Stoyanov
doaj +1 more source
Octahedral Cu(II) perchlorate complexes of n-methyl-2-pyridones
Reaction of hexaaquacopper(II) perchlorate with n-methyl-2-hydroxypyridine generated a family of [(n-methyl-2-pyridone)xCu](ClO4)2 complexes: [(3-methyl-2-pyridone)6Cu](ClO4)2 (1), [(4-methyl-2-pyridone)6Cu](ClO4)2 (2), [(5-methyl-2-pyridone)6Cu](ClO4)2 (
Diane A. Dickie (1331025) +1 more
core +1 more source
Umpolung-like Cross-coupling of Tosylhydrazones with 4‑Hydroxy-2-pyridones under Palladium Catalysis
, 2019 Tosylhydrazones under palladium catalysis were found to perform cross-coupling reactions with 4-hydroxy-2-pyridones. The umpolung-like reactivity, between the α-carbon of tosylhydrazone and the 3-position of the heterocycle, which is observed in the ...
Alexandros L. Zografos (2007229) +2 more
core +1 more source