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On the formation and possible biological role of 25-hydroxycholesterol
Biochimie, 2013The oxysterol 25-hydroxycholesterol is a widely used compound displaying an array of pharmacological actions in in vitro systems and cell based experimental systems. In spite of the frequent use of this compound over the last few decades and a large number of studies in vitro and in vivo, its mechanism of formation in vivo is still not well understood.
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Testosterone regulates 25-hydroxycholesterol production in testicular macrophages.
Biology of reproduction, 2003Recently, we found that testicular macrophages produce 25-hydroxycholesterol (25-HC) and express 25-hydroxylase, the enzyme that converts cholesterol to 25-HC. In addition, 25-HC may be an important paracrine factor mediating the known interactions between macrophages and neighboring Leydig cells, because it is efficiently converted to testosterone by ...
Yevgeniya, Lukyanenko +2 more
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Synthesis of 25-hydroxycholesterol from bisnoralcohol
SteroidsBu-Luan Liang +6 more
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An efficient synthesis of 25-hydroxycholesterol from stigmasterol
Tetrahedron Letters, 1977William G. Salmond, Marie C. Sobala
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