Results 131 to 140 of about 4,298,356 (197)

25-Hydroxycholesterol Induces Intrinsic Apoptosis via Mitochondrial Pathway in BE(2)-C Human Neuroblastoma Cells. [PDF]

Int J Mol Sci
Kim J, Kim K, Park D, Eo SK, Lee BA, Son Y.   +5 more
europepmc   +1 more source

25-Hydroxycholesterol protecting from cerebral ischemia-reperfusion injury through the inhibition of STING activity. [PDF]

Aging (Albany NY), 2021
Lin F, Yao X, Kong C, Liu X, Zhao Z, Rao S, Wang L, Li S, Wang J, Dai Q.   +9 more
europepmc   +1 more source

The role of 25-hydroxycholesterol in the pathophysiology of brain vessel dysfunction associated with infection and cholesterol dysregulation. [PDF]

Dis Model Mech
Tapia VS, Withers SE, Zhou R, Bennington A, Hoyle C, Hedley F, El Khouja A, Luka N, Massimo M, Crilly S, Long KR, Lawrence CB, Kasher PR.   +12 more
europepmc   +1 more source

The cholesterol metabolite 25-hydroxycholesterol restrains the transcriptional regulator SREBP2 and limits intestinal IgA plasma cell differentiation. [PDF]

Immunity, 2021
Trindade BC, Ceglia S, Berthelette A, Raso F, Howley K, Muppidi JR, Reboldi A.   +6 more
europepmc   +1 more source

25-Hydroxycholesterol Inhibits Kaposi's Sarcoma Herpesvirus and Epstein-Barr Virus Infections and Activates Inflammatory Cytokine Responses. [PDF]

mBio, 2021
Serquiña AKP, Tagawa T, Oh D, Mahesh G, Ziegelbauer JM.   +4 more
europepmc   +1 more source

The cholesterol metabolite 25-hydroxycholesterol suppresses porcine deltacoronavirus via lipophagy inhibition and mTORC1 modulation. [PDF]

Vet Res
Zhang JL, Wang XF, Li JL, Duan C, Wang JF.   +4 more
europepmc   +1 more source

Lung-selective 25-hydroxycholesterol nanotherapeutics as a suppressor of COVID-19-associated cytokine storm. [PDF]

Nano Today, 2021
Kim H, Lee HS, Ahn JH, Hong KS, Jang JG, An J, Mun YH, Yoo SY, Choi YJ, Yun MY, Song GY, Joo J, Na DH, Kim HN, Park HH, Lee JY, Lee W.   +16 more
europepmc   +1 more source

25-Hydroxycholesterol modulates microglial function and exacerbates Alzheimer's disease pathology: mechanistic insights and therapeutic potential of cholesterol esterification inhibition. [PDF]

J Neuroinflammation
Choi H, Kim HJ, Lee SE, Song HH, Kim J, Han J, Jeong JH, Lee DY, Chang S, Mook-Jung I.   +9 more
europepmc   +1 more source

25-Hydroxycholesterol 3-Sulfate Recovers Acetaminophen Induced Acute Liver Injury via Stabilizing Mitochondria in Mouse Models. [PDF]

Cells, 2021
Wang Y, Pandak WM, Lesnefsky EJ, Hylemon PB, Ren S.   +4 more
europepmc   +1 more source

Effects of acute pro-inflammatory stimulation and 25-hydroxycholesterol on hippocampal plasticity and learning involve NLRP3 inflammasome and cellular stress responses. [PDF]

Sci Rep
Izumi Y, O'Dell KA, Mennerick S, Zorumski CF.   +3 more
europepmc   +1 more source