Results 151 to 160 of about 4,298,356 (197)

Multiple Roles of 25-Hydroxycholesterol in Lipid Metabolism, Antivirus Process, Inflammatory Response, and Cell Survival. [PDF]

Oxid Med Cell Longev, 2020
Cao Q, Liu Z, Xiong Y, Zhong Z, Ye Q.
europepmc   +1 more source

25-hydroxycholesterol promotes brain endothelial dysfunction by remodelling cholesterol metabolism

Tapia VS, Withers SE, Zhou R, Bennington A, Hedley F, El Khouja A, Luka N, Massimo M, Crilly S, Long KR, Lawrence CB, Kasher PR.   +11 more
europepmc   +1 more source

Deletion of CH25H and LIPA Genes in Human Abolishes Biosynthesis of 25-Hydroxycholesterol but not of 7α,25-Dihydroxysterols and Enhances Non-enzymatic Cholesterol Oxidation: Metabolic Changes are Partially Reversed by Hematopoietic Stem Cell Transplant^‡

Yutuc E, Ghosh A, Abdel-Khalik J, Goenka A, Asgari MA, Lopez-Castejon G, Beaman GM, Wynn RF, Newman WG, Jones SA, Griffiths WJ, Wang Y.   +11 more
europepmc   +1 more source

Some of the next articles are maybe not open access.

Related searches:

25-hydroxycholesterol: Gatekeeper of intestinal IgA

Immunity, 2021
High levels of cholesterol and diets high in fat are associated with immune dysfunction and inflammatory disease. In this issue of Immunity, Trindade et al. (2021) report how the cholesterol metabolite 25-hydroxycholesterol restrains IgA plasma cell differentiation from germinal-center B cells in the Peyer's patches through regulation of the sterol ...
Christopher J M, Piper, Claudia, Mauri
openaire   +2 more sources

Investigation on the synthesis of 25-hydroxycholesterol

Steroids, 2014
A very efficient and environmentally benign method has been developed for the synthesis of 25-hydroxycholesterol. The reaction was performed in THF-water (4:1, v/v) using NBS as the brominating agent, followed by the easy reduction of C-Br with lithium aluminum hydride in THF, to yield the final product corresponding to a Markovnikov's rule.
Qian, Zhao, Li, Ji, Guo-Ping, Qian, Jian-Gang, Liu, Zi-Qiang, Wang, Wan-Feng, Yu, Xin-Zhi, Chen   +6 more
openaire   +2 more sources

Synthesis of ent-25-hydroxycholesterol

Steroids, 2006
25-Hydroxycholesterol (25-HC) appears to play a role in several important biological processes, including regulating cellular cholesterol levels and promoting apoptosis. However, in most cases the mechanisms by which 25-HC elicits its biological effects are not known.
Emily J, Westover, Douglas F, Covey
openaire   +2 more sources

25-Hydroxycholesterols in innate and adaptive immunity

Nature Reviews Immunology, 2014
Cholesterol and components of the cholesterol biosynthetic pathway have fundamental roles in all mammalian cells. Hydroxylated forms of cholesterol are now emerging as important regulators of immune function. This involves effects on the cholesterol biosynthetic pathway and cell membrane properties, which can have antiviral and anti-inflammatory ...
Jason G, Cyster, Eric V, Dang, Andrea, Reboldi, Tangsheng, Yi   +3 more
openaire   +2 more sources

Regulation of Hepatocyte Lipid Metabolism and Inflammatory Response by 25‐Hydroxycholesterol and 25‐Hydroxycholesterol‐3‐sulfate

Lipids, 2010
AbstractDysregulation of lipid metabolism is frequently associated with inflammatory conditions. The mechanism of this association is still not clearly defined. Recently, we identified a nuclear oxysterol, 25‐hydroxycholesterol‐3‐sulfate (25HC3S), as an important regulatory molecule involved in lipid metabolism in hepatocytes.
Leyuan, Xu, Qianming, Bai, Daniel, Rodriguez-Agudo, Phillip B, Hylemon, Douglas M, Heuman, William M, Pandak, Shunlin, Ren   +6 more
openaire   +2 more sources

A new synthesis of 25-hydroxycholesterol

Tetrahedron Letters, 1981
Abstract A simple (η 3 -allyl)palladium-based synthesis of 25-hydroxycholesterol is described using a dimetallated coupling reagent.
Martin Riediker, Jeffrey Schwartz
openaire   +1 more source

Complementary recessive 25‐hydroxycholesterol‐resistant somatic cell mutants – assay of 25‐hydroxycholesterol binding activity

Journal of Cellular Physiology, 1982
AbstractComplementation analysis of recessive 25‐hydroxycholesterol‐resistant mutants of the CHO‐KI cell shows the existence of at least two complementation groups, one of which is missing a binding activity for 25‐hydroxycholesterol. Both complementation groups are shown to be refractory to inhibition of cellular HMG‐CoA reductase activity and in the ...
M, Sinensky, J, Logel, R, Torget
openaire   +2 more sources