Results 121 to 130 of about 3,018,278 (209)

Interferon-Inducible Cholesterol-25-Hydroxylase Broadly Inhibits Viral Entry by Production of 25-Hydroxycholesterol

, 2013
SummaryInterferons (IFN) are essential antiviral cytokines that establish the cellular antiviral state through upregulation of hundreds of interferon-stimulated genes (ISGs), most of which have uncharacterized functions and mechanisms.
Marsden, Matthew D., Li, Guangming, Chikere, Kelechi, Freiberg, Alexander N., Lee, Benhur, Nusbaum, Rebecca, Su, Lishan, Cheng, Genhong, Guo, Haitao, Zack, Jerome A., Smith, Jennifer K., Liu, Su-Yang, Pernet, Olivier, Aliyari, Roghiyh   +13 more
core   +1 more source

Studies on 4b-hydroxycholesterol, a marker of CYP3A activity, and its association with 25-hydroxyvitamin D [Elektronisk resurs]

, 2015
Cholesterol is a vital compound that can undergo cytochrome P450 (CYP) mediated conversion into steroid hormones, bile acids and oxysterols. CYP enzymes are present in all human tissues and mediate the metabolism of several endogenous and exogenous ...
Nylén, H
core  

Bobbing of 27-hydroxycholesterol.

, 2018
<p>Movie showing the bobbing of 27-hydroxycholesterol.</p ...
Kulig, Waldemar, Kulig, Waldemar (5268277)   +1 more
core   +1 more source

Cholesterol 25-hydroxylase inhibits Newcastle disease virus replication by enzyme activity-dependent and direct interaction with nucleocapsid protein

Journal of Virology
Newcastle disease virus (NDV) is a significant enveloped virus within the Paramyxoviridae family, posing a major threat to the global poultry industry.
Guangmei Zhu, Xianchun Zong, Mengmeng Xiao, Dan Wang, Zhe Xu, Jingtao Hu, Guilian Yang, Yanlong Jiang, Wentao Yang, Haibin Huang, Chunwei Shi, Yan Zeng, Nan Wang, Xin Cao, Jianzhong Wang, Chunfeng Wang   +15 more
doaj   +1 more source

Hepatic uptake and metabolism of ingested 24-hydroxycholesterol and 24(S),25-epoxycholesterol.

, 1993
Although two hepatic sterol metabolites, 24(S)-hydroxycholesterol and 24(S),25-epoxycholesterol, are thought to be important regulators of cholesterol biosynthesis, nothing is known of their degradation and disposal in liver, nor of the mechanisms ...
Kandutsch, A A, Spencer, T A, Clark, D S, Saucier, S E   +3 more
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25-Hydroxycholesterol regulates cholesterol homeostasis in the murine CATH.a neuronal cell line

, 2013
Aberrant oxysterol biosynthesis is implicated in the pathogenesis of neurodegenerative diseases. During the present study we have investigated the effects of exogenously added 25-hydroxycholesterol (25-HC) on transcription of cholesterol biosynthetic ...
Waltl, Sabine, Nusshold, Christoph, Eibinger, Gerald, Fauler, Günter, Wintersperger, Andrea, Üllen, Andreas, Kratky, Dagmar, Malle, Ernst, Sattler, Wolfgang, Patankar, Jay. V.   +9 more
core   +1 more source

Regulation of astrocyte lipid metabolism and ApoE secretionby the microglial oxysterol, 25-hydroxycholesterol. [PDF]

J Lipid Res, 2023
Cashikar AG, Toral-Rios D, Timm D, Romero J, Strickland M, Long JM, Han X, Holtzman DM, Paul SM.   +8 more
europepmc   +1 more source

27-Hydroxycholesterol modulation of low density lipoprotein metabolism in cultured human hepatic and extrahepatic cells

, 1993
27-Hydroxycholesterol11Recent publications have chosen to use 27-hydroxycholesterol rather than the conventional name 26-hydroxycholesterol to indicate that the mitochondrial enzyme stereospecifically hydroxylates only the methyl group in position C-27 ...
Stefane Bellosta, S. Bellosta, Bellosta, Stefane, A. Granata, Granata A, Fumagalli, Remo, Didoni, Guido, Bernini, Franco, Corsini A, M. Mazzotti, F. Bernini, A. Corsini, R. Fumagalli, Mazzotti, Maria, G. Didoni, Fumagalli R., Didoni G, Agnese Granata, Granata, Agnese, Bellosta S, Alberto Corsini, Guido Didoni, Maria Mazzotti, Franco Bernini, Mazzotti M, Corsini, Alberto, Bernini F, Remo Fumagalli   +27 more
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Serum 25-hydroxycholesterol levels are increased in patients with coronavirus disease 2019. [PDF]

J Clin Lipidol, 2023
Asano T, Wakabayashi T, Kondo Y, Okada K, Yamamuro D, Koga Y, Oka K, Sakurai M, Sawayama N, Takahashi M, Okazaki H, Ebihara K, Minami K, Morisawa Y, Hatakeyama S, Matsumura M, Ishibashi S.   +16 more
europepmc   +1 more source

Suppression of endocytosis in polyclonally activated Con A-stimulated T lymphocytes by 25-hydroxycholesterol.

, 1983
Endocytosis in polyclonally activated, Con A-stimulated spleen cell cultures was analyzed. It was found that as lymphocytes differentiate to acquire cytotoxic capability their endocytic activity also increases, reaching a plateau at 48 hr.
Sodergren, A, Heiniger, H J, Marshall, J D   +2 more
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