Results 101 to 110 of about 3,018,278 (209)
, 2019 Mitochondrial dysfunction and oxidative stress are involved in neurodegenerative diseases associated with an enhancement of lipid peroxidation products such as 7β-hydroxycholesterol (7β-OHC).
Ilham Badreddine (6838493) +14 more
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Journal of Neurochemistry, Volume 170, Issue 6, June 2026.Brain cholesterol homeostasis is tightly regulated and largely independent of peripheral cholesterol. This review proposes a unifying framework in which aging, sex, and related biological stressors, including hypercholesterolemia, neurodegeneration, inflammation, and oxidative stress, converge to disrupt cholesterol homeostasis in the brain ...
Myuri Ruthirakuhan +2 more
wiley +1 more source
25-Hydroxycholesterol-induced elevation in 45Ca uptake: correlation with depressed DNA synthesis.
, 1984 The mechanism whereby 25-hydroxycholesterol, an inhibitor of the synthesis of cholesterol, depresses DNA synthesis in cycling P815 mastocytoma cells was investigated. The uptake of 45Ca into P815 cells treated with 1 microgram/ml 25-hydroxycholesterol
Heiniger, H J, Boissonneault, G A
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25-Hydroxycholesterol-induced elevations in 45Ca uptake: permeability changes in P815 cells.
, 1985 Certain oxysterols are capable of suppressing the activity of 3-hydroxy-3-methylglutaryl coenzyme A (HMG CoA) reductase. We have previously demonstrated that treatment of P815 cells with 1 microgram 25-hydroxycholesterol/ml culture results in a rapid ...
Heiniger, H J, Boissonneault, G A
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Role for ORPs in 25‐hydroxycholesterol binding to SCAP
The FASEB Journal, 2006 The mechanism by which 25‐hydroxycholesterol influences intracellular lipid homeostasis is not well understood. This oxysterol is known to be ten times more potent inhibitor of SCAP‐SREBP translocation to the Golgi than cholesterol itself, however, the question if it acts directly on SCAP or if it influences its function indirectly remains open.
Monika Suchanek +3 more
openaire +1 more source
, 1990 Resum informatiu de com és un programa darrere de les càmeres amb la visita de nens al plató de ...
Canal 25 (25 Televisió)
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A Concise Synthesis of 25-Hydroxycholesterol from Hyodesoxycholic Acid
, 2018 A simple, efficient and economical method has been developed for the synthesis of 25-hydroxycholesterol in seven steps from hyodesoxycholic acid with an overall yield of 39%.
Yulei Wang, Bin Sun, Weike Su, Can Jin
core +1 more source
, 1977 When 25-hydroxycholesterol or 7-ketocholesterol was fed to mice with the diet, growth was suppressed and mature mice lost weight. The effect of the 7-ketone upon body weight was effectively counteracted by cholesterol whereas cholestanol and beta ...
Kandutsch, A A +3 more
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Cellular and Molecular Life SciencesBackground and aims Oxysterols, oxidized derivatives of cholesterol, play complex roles in inflammatory processes, but their specific functions in inflammatory bowel diseases remain incompletely understood.
Hafsa Ameraoui +6 more
doaj +1 more source