Results 91 to 100 of about 4,298,356 (197)

Cholesterol, oxysterol, triglyceride, and coenzyme Q homeostasis in ALS. Evidence against the hypothesis that elevated 27-hydroxycholesterol is a pathogenic factor.

PLoS ONE, 2014
High plasma levels of cholesterol have been suggested to be neuroprotective for the degenerative disease amyotrophic lateral sclerosis (ALS) and to be associated with increased survival time.
Anna Wuolikainen, Jure Acimovic, Anita Lövgren-Sandblom, Paolo Parini, Peter M Andersen, Ingemar Björkhem, Ingemar Björkhem   +6 more
doaj   +1 more source

Canal 25 : videoescoles : mirar-se i millorar-se

, 1990
Congrés realitzat pel Canal 25 que tracta sobre com ha sigut la inversió tecnològica a les escoles amb feedback per part de l'estudiant i ...
Canal 25 (25 Televisió)
core  

Identification of regulatory oxysterols, 24(S),25-epoxycholesterol and 25-hydroxycholesterol, in cultured fibroblasts.

, 1985
Biosynthetically tritiated sterols from Chinese hamster lung (Dede) cells were fractionated by high performance liquid chromatography, and fractions were assayed for their ability to repress 3-hydroxy-3-methylglutaryl-CoA reductase in L cell cultures.
Kandutsch, A A, Gayen, A K, Spencer, T A, Saucier, S E, Phirwa, S, Taylor, F R   +5 more
core   +1 more source

25-Hydroxycholesterol and 27-hydroxycholesterol inhibit human rotavirus infection by sequestering viral particles into late endosomes

Redox Biology, 2018
A novel innate immune strategy, involving specific cholesterol oxidation products as effectors, has begun to reveal connections between cholesterol metabolism and immune response against viral infections.
Andrea Civra, Rachele Francese, Paola Gamba, Gabriella Testa, Valeria Cagno, Giuseppe Poli, David Lembo   +6 more
doaj   +1 more source

Effects of 26-aminocholesterol, 27-hydroxycholesterol, and 25-hydroxycholesterol on proliferation and cholesterol homeostasis in arterial myocytes

, 1995
The major relation existing between cell growth and cholesterol homeostasis prompted us to investigate the effect of 26-aminocholesterol (26-NH2), 27-hydroxycholesterol (27-OH), and 25-hydroxycholesterol (25-OH) on these cellular events.
R. Paoletti, D. Verri, P. Quarato, M. Raiteri, A. Corsini, R. Fumagalli   +5 more
core   +1 more source

Studies on 4b-hydroxycholesterol, a marker of CYP3A activity, and its association with 25-hydroxyvitamin D

, 2015
Cholesterol is a vital compound that can undergo cytochrome P450 (CYP) mediated conversion into steroid hormones, bile acids and oxysterols. CYP enzymes are present in all human tissues and mediate the metabolism of several endogenous and exogenous ...
Hanna Nylén (18685588)
core   +1 more source

Oxysterol-mediated modulation of intestinal inflammation: insights into sex differences and GPR183 signaling

Cellular and Molecular Life Sciences
Background and aims Oxysterols, oxidized derivatives of cholesterol, play complex roles in inflammatory processes, but their specific functions in inflammatory bowel diseases remain incompletely understood.
Hafsa Ameraoui, Joan Bestard-Escalas, Martin Roumain, Adam Laghouati, Pauline Bottemanne, Mireille Alhouayek, Giulio G. Muccioli   +6 more
doaj   +1 more source

Role for ORPs in 25‐hydroxycholesterol binding to SCAP

The FASEB Journal, 2006
The mechanism by which 25‐hydroxycholesterol influences intracellular lipid homeostasis is not well understood. This oxysterol is known to be ten times more potent inhibitor of SCAP‐SREBP translocation to the Golgi than cholesterol itself, however, the question if it acts directly on SCAP or if it influences its function indirectly remains open.
Monika Suchanek, Anna Radzikowska, Vesa Olkkonen, Christoph Thiele   +3 more
openaire   +1 more source

Editorial: 25-Hydroxycholesterol: a new life in immunology

Journal of Leukocyte Biology, 2010
Abstract A discussion on paper by Park and Scott revealing the signaling pathways leading to the synthesis of a potent immunoregulatory oxysterol by macrophage and dendritic cells.
Jeffrey G McDonald, David W Russell
openaire   +2 more sources

25-Hydroxycholesterol Activates a Cytochrome C Release-Mediated Caspase Cascade

, 2000
We have previously shown that 25-hydroxycholesterol (25-OHC) treated CHO-K1 cells could be used as a model to investigate the signaling pathway of apoptosis induced by oxidized LDL in vascular cells.
Sinensky, Michael S., Yang, Lin
core   +1 more source