Results 41 to 50 of about 136,200 (251)
PLoS Neglected Tropical Diseases, 2022 The parasite Trypanosoma brucei grows as bloodstream forms in mammalian hosts, and as procyclic forms in tsetse flies. In trypanosomes, gene expression regulation depends heavily on post-transcriptional mechanisms.
Tania Bishola Tshitenge +3 more
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Translational Efficiency Is Regulated by the Length of the 3′ Untranslated Region [PDF]
Molecular and Cellular Biology, 1996 All polyadenylated mRNAs contain sequence of variable length between the coding region and the poly(A) tail. Little has been done to establish what role the length of the 3' untranslated region (3'UTR) plays in posttranscriptional regulation. Using firefly luciferase (luc) reporter mRNA in transiently transfected Chinese hamster ovary (CHO) cells, we ...
R L, Tanguay, D R, Gallie
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Is there a classical nonsense-mediated decay pathway in trypanosomes? [PDF]
PLoS ONE, 2011 In many eukaryotes, messenger RNAs with premature termination codons are destroyed by a process called "nonsense-mediated decay", which requires the RNA helicase Upf1 and also, usually, an interacting factor, Upf2.
Praveen Delhi +4 more
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Post-transcriptional control of nuclear-encoded cytochrome oxidase subunits in Trypanosoma brucei:evidence for genome-wide conservation of life-cycle stage-specific regulatory elements [PDF]
, 2006 Trypanosomes represent an excellent model for the post-transcriptional regulation of gene expression because their genome is organized into polycistronic transcription units.
Katelyn Fenn +10 more
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Alternative polyadenylation and polymorphisms of 3'untranslated regions of bovine BBOX1 gene
Czech Journal of Animal Science, 2018 l-Carnitine, a key element in fatty acid metabolism and energy production, is biosynthesized from gamma-butyro-betaine by the catalysis of gamma-butyrobetaine hydroxylase (BBOX1).
Guo-Li Zhou +4 more
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Characterization of 3'-untranslated region of the mouse GDNF gene [PDF]
BMC Molecular Biology, 2012 Abstract Background Glial cell line-derived neurotrophic factor (GDNF) is a potent survival factor for many cell types, and its expression is widespread both within and outside of the nervous system. The regulation of GDNF expression has been extensively investigated but is not fully understood.
Oh-hashi, Kentaro +2 more
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, 2009 Recently a first genome-wide analysis of translational regulation using prokaryotic species had been performed which revealed that regulation of translational efficiency plays an important role in haloarchaea.
Jörg Soppa +5 more
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Leveraging omic features with F3UTER enables identification of unannotated 3’UTRs for synaptic genes
Nature Communications, 2022 3’ untranslated regions (3’UTRs) play a crucial role in regulating gene expression, but our 3’UTR catalogue is incomplete. Here, the authors develop a machine learning-based framework to predict previously unannotated 3’UTRs in 39 human tissues.
Siddharth Sethi +8 more
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BMC Bioinformatics, 2007 Background Short (~5 nucleotides) interspersed repeats regulate several aspects of post-transcriptional gene expression. Previously we developed an algorithm (REPFIND) that assigns P-values to all repeated motifs in a given nucleic acid sequence and ...
Ferenc Matthew T +8 more
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Untranslated Regions of a Mobile Transcript Mediate RNA Metabolism
, 2009 BEL1-like transcription factors are ubiquitous in plants and interact with KNOTTED1 types to regulate numerous developmental processes. In potato (Solanum tuberosum subsp.
Hannapel, David J. +2 more
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