Discovering non-coding RNA elements in Drosophila 3' untranslated regions. [PDF]
The Non-Coding RNA (ncRNA) elements in the 3′ Untranslated Regions (3′-UTRs) are known to participate in the genes\u27 post-transcriptional regulations.
Zhong C, Andrews J, Zhang S.
europepmc +2 more sources
Tomato torrado virus (ToTV) induces severe systemic necrosis in Solanum lycopersicum. This work aimed at describing the genetic variability of necrosis-inducing ToTV-Wal’17 collected in 2017, derived from the ToTV-Wal’03 after long-term passages in ...
Marta Budziszewska +1 more
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Regulation of CCN1 via the 3′-untranslated region [PDF]
The 3'-untranslated region (UTR) is known to be a critical regulator of post-transcriptional events that determine the gene expression at the RNA level. The gene CCN1 is one of the classical members of the matricellular CCN family and is involved in a number of biological processes during mammalian development.
Yosuke, Nakagawa +8 more
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The 3' untranslated regions of influenza genomic sequences are 5'PPP-independent ligands for RIG-I. [PDF]
Retinoic acid inducible gene-I (RIG-I) is a key regulator of antiviral immunity. RIG-I is generally thought to be activated by ssRNA species containing a 5'-triphosphate (PPP) group or by unphosphorylated dsRNA up to ~300 bp in length. However, it is not
William G Davis +12 more
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Characterization of Single Nucleotide Variants of OPN3 Gene in Melanocytic Nevi and Melanoma
In this study, we examined single nucleotide variants (SNVs) of the OPN3 gene in malignant melanoma and melanocytic nevi. A total of 20 variants of SNVs were detected.
Wei Zhang +5 more
doaj +1 more source
Alternative Polyadenylation in Human Diseases [PDF]
Varying length of messenger RNA (mRNA) 3′-untranslated region is generated by alternating the usage of polyadenylation sites during pre-mRNA processing.
Jae-Woong Chang +2 more
doaj +1 more source
Transcriptional Repression, a Novel Function for 3' Untranslated Regions [PDF]
The transcription rates of the rat serine protease inhibitor 2.3 and 2.1 genes (spi 2.3 and spi 2.1), which are normally very low and high, respectively, are inversely modulated during inflammation. Two growth‐hormone‐response elements (GHRE‐I and GHRE‐II) maintain the spi 2.1 gene under the stringent control of growth hormone [Le Cam, A., Pantescu, V.,
A, Le Cam, C, Legraverend
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The effect of the length of the 3′‐untranslated region on expression in plants [PDF]
The effect of increasing the length of the 3′‐untranslated region (UTR) on expression of luciferase mRNA was examined in transiently transfected carrot protoplasts. The effect of the 3′‐UTR on both poly(A)− and poly(A)+ mRNA was examined. A nested set of constructs in which the 3′‐UTR increased from 4 to 104 bases was generated by the introduction and ...
Tanguay, Robert L., Gallie, Daniel R.
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Genomic Analysis of miR-21-3p and Expression Pattern with Target Gene in Olive Flounder [PDF]
MicroRNAs (miRNAs) act as regulators of gene expression by binding to the 3’ untranslated region (UTR) of target genes. They perform important biological functions in the various species.
Ara Jo, Hee-Eun Lee, Heui-Soo Kim
doaj +1 more source
The ODC 3′-Untranslated Region and 5′-Untranslated Region Contain cis-Regulatory Elements: Implications for Carcinogenesis [PDF]
It has been hypothesized that both the 3′-untranslated region (3′UTR) and the 5′-untranslated region (5′UTR) of the ornithine decarboxylase (ODC) mRNA influence the expression of the ODC protein. Here, we use luciferase expression constructs to examine the influence of both UTRs in keratinocyte derived cell lines. The ODC 5′UTR or 3′UTR was cloned into
Shannon Nowotarski, Lisa Shantz
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