Results 81 to 90 of about 17,890 (211)
Studies in Conjugated lmines: Nucleophilic Additions and the 1 ,3-Dipolar Cycloadditions
, 1970 Studies in Conjugated lmines: Nucleophilic Additions and the 1 ,3-Dipolar ...
Singh, Nazar, P. S. Sethi
openaire +1 more source
The FEBS Journal, EarlyView.Characterization of anhydromevalonate phosphate decarboxylase, the UbiD‐family decarboxylase involved in the archaeal mevalonate pathway, was conducted. The enzyme is responsible for the biosynthesis of isoprenoids, such as archaeal membrane lipids, respiratory quinones, and dolichols.
Rino Ishikawa +9 more
wiley +1 more source
Beilstein Journal of Organic Chemistry, 2014 A new series of pyrrolo[3′,4′:3,4]pyrrolo[1,2-a]furoquinolines/phenanthrolines and pyrrolo[1,2-a]phenanthrolines were efficiently built up from an 8-hydroxyquinoline derivative or phenanthroline via 1,3-dipolar cycloaddition reaction involving non ...
Rupankar Paira +8 more
doaj +1 more source
Synthesis of 3,5-Disubstituted Isoxazoles and Isoxazolines in Deep Eutectic Solvents [PDF]
, 2015 The synthesis of different 3,5-disubstituted isoxazoles and related isoxazolines using choline chloride:urea as deep eutectic solvent (DES) in a one-pot three step reaction has been accomplished successfully. The use of highly nucleophilic functionalized
Pérez Galera, Juana María +1 more
core +3 more sources
Targeting Expanded CUG and CTG Repeats as a Therapeutic Approach for Myotonic Dystrophy Type 1 (DM1)
ChemMedChem, Volume 21, Issue 5, 13 March 2026.DM1 is an RNA gain‐of‐function disease caused by CTG repeat expansion, producing toxic r(CUG)exp RNA that sequesters MBNL1 and impairs splicing. This review covers the field of CUG and CTG ligands identified or rationally designed as DM1 drug candidates, highlighting their molecular design, RNA‐ or DNA‐binding modes, in vitro affinities and ...
Camille Richagneux, Anton Granzhan
wiley +1 more source
Synthetic chemistry and biological activity of pentafluorosulphanyl (SF5) organic molecules [PDF]
, 2012 Acknowledgements We thank the European Commission for financial support (Industry Academia Partnerships and Pathways project “PET BRAIN”, Contract No 251482). S.A.
Altomonte, Stefano, Zanda, Matteo
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Reversible Nanocomposites With Carbon Nanotubes as the Diene in the Diels–Alder Reaction
Polymer Composites, Volume 47, Issue 5, Page 4159-4170, 10 March 2026.Scheme of the reversible nanocomposites through DA and rDA reactions with participation of carbon nanotubes. ABSTRACT Carbon nanotubes (CNTs) often require surface functionalization to facilitate uniform distribution and address issues related to aggregation. Due to the sp2 hybridized carbon atoms on their surface, CNTs readily participate in the Diels–
Jie Guo +3 more
wiley +1 more source
Synthesis of Spiroisoxazolines by 1,3-Dipolar Cycloaddition
Molecules, 1997 The cycloaddition of the chiral nitrile oxide 1 to 1-R-substituted 3,3-methylene-5,5-dimethyl-2-pyrrolidinones 2 (where R is H, n-butyl-, 1,1-dimethylethoxycarbonyl-, 1-methylethenyl- and acetyl-) proceeds regioselectively under the formation of ...
Peter Ertl +3 more
doaj +1 more source
Copper Nanoparticles in Click Chemistry [PDF]
, 2015 Conspectus: The challenges of the 21st century demand scientific and technological achievements that must be developed under sustainable and environmentally benign practices.
Alonso, Francisco +2 more
core +2 more sources
Chemistry – A European Journal, Volume 32, Issue 10, 9 March 2026.Novel analogues of the kinetoplastid‐specific DNA base J unlock a new way to target parasite epigenetic regulation. Some compounds selectively inhibit Leishmania and Trypanosoma species without harming human cells, revealing a promising route toward innovative antiparasitic therapies.
Océane Monfret +9 more
wiley +1 more source