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Enzymatic esterification of 3-hydroxybutyric acid

Biotechnology Letters, 1993
Candida cylindracea lipase catalysed esterification of (±)-3-hydroxybutyric acid (1) with n-butanol was studied in different solvents. This provided an alternative preparative method for the versatile chiron. butyl (S)-3-hydroxybutyrate (2) via kinetic resolution of (±)-1 With toluene as the reaction medium, the enantioselection was found to be ...
S. Chattopadhyay, V. R. Mamdapur
openaire   +1 more source

Hypothalamic neuronal activity responses to 3-hydroxybutyric acid, an endogenous organic acid

Brain Research, 1990
To elucidate the anorectic action of the endogenous organic acid, 3-hydroxybutyric acid (3-HBA), its effects on neurons in both the rat ventromedial hypothalamic nucleus (VMH) and the lateral hypothalamic area (LHA) were examined. Iontophoretic application of 3-HBA significantly facilitated the firing rate of VMH neurons, whereas facilitation and ...
T, Minami   +3 more
openaire   +2 more sources

Catalyst-free valorization of poly-3-hydroxybutyrate to crotonic acid

Reaction Chemistry & Engineering, 2021
A novel catalyst-free valorization process of PHB to CA in inert nonpolar solvents is developed. CA was obtained with a yield of 89 wt% and a purity of 91% via a simple consecutive process of pyrolysis at 210 °C and vacuum distillation at 60 °C.
Shimin Kang   +6 more
openaire   +1 more source

Accumulation of Poly (3-Hydroxybutyric Acid) by Some Soil Streptomyces

Current Microbiology, 1999
In a limited-scale survey, 55 soil streptomycetes were screened for the accumulation of poly (3-hydroxybutyrate) [PHB]. Only 18% of the isolates accumulated PHB ranging between 1.9-7.8% of the dry biomass. The promising isolate DBCC-719, identified as Streptomyces griseorubiginosus, accumulated PHB amounting to 9.5% of the mycelial dry mass in the ...
A, Manna, R, Banerjee, A K, Paul
openaire   +2 more sources

Properties and drug release behaviour of poly(3-hydroxybutyric acid) and various poly(3-hydroxybutyrate-hydroxyvalerate) copolymer microcapsules

Journal of Microencapsulation, 1995
Microcapsules of poly(3-hydroxybutyric acid) [PHB] and its copolymers with hydroxyvalerate [HV] were prepared by the solvent evaporation technique and loaded with a model drug, 2,7-dichlorofluorescein. Microcapsules were also prepared from the same polymers by incorporating a polyphosphate-Ca+2 complex into the membrane.
I, Gürsel, V, Hasirci
openaire   +2 more sources

Omega oxidation of fatty acids and the pathway of 3-hydroxybutyric acid formation

Archives of Biochemistry and Biophysics, 1978
Abstract Pathways followed by the carbons of long chain fatty acids in their conversion to 3-hydroxybutyric acid were traced and the contribution of ω-oxidation to fatty acid oxidation was determined in the cellular environment where ketone body formation occurs.
W C, Schumann   +2 more
openaire   +2 more sources

Model-based optimization of the enzymatic aldol addition of propanal to formaldehyde: A first step towards enzymatic synthesis of 3-hydroxybutyric acid

Chemical engineering research & design, 2019
3-Hydroxyisobutyric acid is an important intermediate in the biosynthesis of methacrylic acid. Its biocatalytic synthesis can be performed by aldolase-catalyzed aldol addition of propanal to formaldehyde followed by an enzymatic oxidation of the ...
Morana Česnik   +8 more
semanticscholar   +1 more source

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