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Estimation of the tryptophan metabolites xanthurenic acid, 3-hydroxykynurenine and kynurenine
Clinica Chimica Acta, 1967Abstract Colorimetric methods for estimating xanthurenic acid and 3-hydroxykynurenine by their reaction with diazotized sulphanilic acid have been investigated. Modification of these methods eliminates the difficulties previously found in estimating these metabolites. A covering layer of butanol is used to prevent atmospheric oxidation of the colours.
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INCREASED BRAIN 3-HYDROXYKYNURENINE IN HUNTINGTON'S DISEASE
The Lancet, 1989G P, Reynolds, S J, Pearson
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Elucidating the role of 3-hydroxykynurenine on neuronal physiology
The kynurenine pathway (KP) is the primary route for dietary tryptophan catabolism and culminates in NAD production. Several KP metabolites have neuromodulator functions and dysregulation of the KP is observed in a range of neurological disorders. Previous studies have suggested that the KP metabolite 3-hydroxykynurenine (3-HK) is a neurotoxin at ...openaire +1 more source
3-Hydroxykynurenine-keto-C14: A precursor of urinary quinolinic acid
Biochemical and Biophysical Research Communications, 1961L V, HANKES, R R, BROWN
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