Results 1 to 10 of about 2,046 (63)

Synthesis and evaluation of 4-[18F]fluoropropoxy-3-iodobenzylguanidine ([18F]FPOIBG): A novel 18F-labeled analogue of MIBG. [PDF]

Nucl Med Biol, 2015
Radioiodinated meta-iodobenzylguanidine (MIBG), a norepinephrine transporter (NET) substrate, has been extensively used as an imaging agent to study the pathophysiology of the heart and for the diagnosis and treatment of neuroendocrine tumors. The goal of this study was to develop an (18)F-labeled analogue of MIBG that like MIBG itself could be ...
Vaidyanathan G, McDougald D, Koumarianou E, Choi J, Hens M, Zalutsky MR.   +5 more
europepmc   +5 more sources

Value of multi-parameter 123I-MIBG scintigraphy in the differential diagnosis of Parkinson’s disease [PDF]

EJNMMI Research
Background 123I-MIBG scintigraphy plays a significant role in diagnosing Parkinson's disease (PD), with most studies primarily targeting cardiac uptake and relying on traditional ratio-based parameters for assessment.
Teng Xue, Ying Cui, Ying Kan, Guanyun Wang, Jigang Yang   +4 more
doaj   +2 more sources

Treatment outcomes of high-dose chemotherapy plus stem cell rescue in high-risk neuroblastoma patients in Thailand [PDF]

Clinical and Experimental Pediatrics, 2022
Background In 2013, the Thai Pediatric Oncology Group (ThaiPOG) introduced a national protocol in which high-dose chemotherapy plus stem cell rescue is performed without immunotherapy.
Kunanya Suwannaying, Piti Techavichit, Patcharee Komvilaisak, Napat Laoaroon, Nattee Narkbunnam, Kleebsabai Sanpakit, Kanhatai Chiengthong, Thirachit Chotsampancharoen, Lalita Sathitsamitphong, Chalongpon Santong, Panya Seksarn, Suradej Hongeng, Surapon Wiangnon   +12 more
doaj   +1 more source

A Case of Pure Autonomic Failure Initially Presenting with Hemihypohidrosis: Twelve-Year Follow-Up

Case Reports in Neurology, 2022
Although it is generally recognized that pure autonomic failure (PAF) is a progressive neurodegenerative disease selectively involving the autonomic nervous system, its mode of progression remains to be settled.
Hiroshi Saito
doaj   +1 more source

Microwave Irradiation Assisted Synthesis 4-Hydroxy 3-Iodobenzylguanidine(HIBG) [PDF]

Ciência e Natura, 2015
Meta-iodo benzyl guanidine(MIBG) is an analogue of Noradernalin transmitter. When radiolabelled with 123 I and 131I , used for scan and diagnosis Adernal’s tumor. Labeled MIBG with 131I used in therapy of Neuroblastoma , Pheochromocytoma , Carcinoidsyndome and Neuroendocrine tumors.
M. Poursharifi, S. Shahi
openaire   +1 more source

Exploring the link between essential tremor and Parkinson’s disease

npj Parkinson's Disease, 2023
Epidemiological studies have reported a link between essential tremor (ET) and Parkinson’s disease (PD). Recent studies have suggested ET as a possible neurodegenerative disease whose subgroup contained Lewy bodies in the brainstem, as in PD.
Sang-Won Yoo, Seunggyun Ha, Chul Hyoung Lyoo, Yuna Kim, Ji-Yeon Yoo, Joong-Seok Kim   +5 more
doaj   +1 more source

The Current Status and Future Potential of Theranostics to Diagnose and Treat Childhood Cancer

Frontiers in Oncology, 2020
In theranostics (i.e., therapy and diagnostics) radiopharmaceuticals are used for both therapeutic and diagnostic purposes by targeting one specific tumor receptor.
Alex J. Poot, Alex J. Poot, Marnix G. E. H. Lam, Max M. van Noesel   +3 more
doaj   +1 more source

Efeito do carvedilol a curto prazo na atividade simpática cardíaca pela cintilografia com 123I-MIBG Effects of short-term carvedilol on the cardiac sympathetic activity assessed by 123I-MIBG scintigraphy

Arquivos Brasileiros de Cardiologia, 2010
FUNDAMENTO: Alterações autonômicas na insuficiência cardíaca estão associadas a um aumento da morbimortalidade. Vários métodos não invasivos têm sido empregados para avaliar a função simpática, incluindo a imagem cardíaca com 123I-MIBG. OBJETIVO: Avaliar
Sandra Marina Ribeiro de Miranda, Evandro Tinoco Mesquita, Hans Fernando da Rocha Dohmann, Jader Cunha Azevedo, Gustavo Borges Barbirato, Fabiano de Lima Freire, Mário Luiz Ribeiro, Antonio Cláudio Lucas da Nóbrega, Alexandro Coimbra, Cláudio Tinoco Mesquita   +9 more
doaj   +1 more source

Incorporation of high-dose 131I-metaiodobenzylguanidine treatment into tandem high-dose chemotherapy and autologous stem cell transplantation for high-risk neuroblastoma: results of the SMC NB-2009 study

Journal of Hematology & Oncology, 2017
Background In our previous SMC NB-2004 study of patients with high-risk neuroblastomas, which incorporated total-body irradiation (TBI) with second high-dose chemotherapy and autologous stem cell transplantation (HDCT/auto-SCT), the survival rate was ...
Ji Won Lee, Sanghoon Lee, Hee Won Cho, Youngeun Ma, Keon Hee Yoo, Ki Woong Sung, Hong Hoe Koo, Eun Joo Cho, Suk-Koo Lee, Do Hoon Lim   +9 more
doaj   +1 more source

A novel approach in the treatment of neuroendocrine gastrointestinal tumors: Additive antiproliferative effects of interferon-γ and meta-iodobenzylguanidine

BMC Cancer, 2004
Background Therapeutic options to effectively inhibit growth and spread of neuroendocrine gastrointestinal tumors are still limited. As both meta-iodobenzylguanidine (MIBG) and interferon-γ (IFNγ) cause antineoplastic effects in neuroendocrine ...
Ahnert-Hilger Gudrun, Huether Alexander, Sutter Andreas P, Höpfner Michael, Scherübl Hans   +4 more
doaj   +1 more source