Results 31 to 40 of about 5,846 (172)

Scientific Report on consumer health‐based guidance values for trifluoroacetic acid

EFSA Journal, Volume 24, Issue 7, July 2026.
Abstract The European Commission asked EFSA to provide a scientific report according to Article 31 of Regulation (EC) No 178/2002, in conjunction with Regulation (EC) No 1107/2009, to revise consumer health‐based guidance values, i.e. acceptable daily intake (ADI) and acute reference dose (ARfD), for trifluoroacetic acid (TFA). EFSA launched a targeted
EFSA (European Food Safety Authority), Adeline Cavelier, Tamara Coja, Andrea Gall, Antonio Hernández‐Jerez, Christiane Vleminckx, Elodie Bergsma, Marco Binaglia, Federica Crivellente, Mathilde Colas, Anna Lanzoni, Jochem Louisse, Rafaela Rodrigues De Jesus, Annetta Grillo, Iris Mangas, Juan Manuel Parra Morte   +15 more
wiley   +1 more source

MyoRep: A Novel Reporter System to Detect Early Muscle Atrophy In Vitro and In Vivo

Journal of Cachexia, Sarcopenia and Muscle, Volume 17, Issue 3, June 2026.
ABSTRACT Background Muscle atrophy occurs during physiological (i.e., fasting) and pathological conditions (i.e., cancer) and anticipates death. Since not all patients will undergo muscle wasting, it would be highly useful to identify them soon to intervene early.
Andrea D. Re Cecconi, Nicoletta Rizzi, Mara Barone, Federica Palo, Martina Lunardi, Mara Forti, Adriana Maggi, Paolo Ciana, Giulia Terribile, Michela Chiappa, Lorena Zentilin, Rosanna Piccirillo   +11 more
wiley   +1 more source

Transcriptomic Profiling of HepaRG Cells During Differentiation and 3-Methylcholanthrene Induction Using Oxford Nanopore Direct RNA Sequencing

Data
The aryl hydrocarbon receptor (AhR) plays a crucial role in mediating xenobiotic responses, as well as regulating broader metabolic, differentiation, and stress response programs. In this study, we present a comprehensive long-read RNA sequencing dataset
Nataliya G. Luzgina, Svetlana N. Tarbeeva, Daniil D. Romashin, Konstantin G. Ptitsyn, Svetlana A. Khmeleva, Leonid K. Kurbatov, Sergey P. Radko, Anna S. Kozlova, Polina A. Veselova, Ekaterina V. Ilgisonis, Alexander L. Rusanov   +10 more
doaj   +1 more source

Aristolochic Acid Affects Upper Tract Urothelial Cancer Behavior through the MAPK Pathway

Molecules, 2019
The prevalence of upper tract urothelial carcinoma (UTUC) in Taiwan is relatively higher than thatin Western countries. Aristolochic acid (AA), which is widely used in traditional Chinese herbology, is now recognized to be one of the carcinogens for UTUC.
I-Hsuan Chen, Hao-Lun Luo, Yu-Li Su, Chun-Chieh Huang, Po-Hui Chiang, Chia-Cheng Yu, Nai-Lun Lee, Jen-Jie Lin, Ming-Tse Sung   +8 more
doaj   +1 more source

Chemopreventive effects of Prunus cerasus L. against human cancer cells & ascites mice models and its phytochemical investigation by LC-Q-TOF-MS/MS

Phytomedicine Plus, 2022
Background: Berries, including cherries and their derived distinctive bioactive leads, are explored for the establishment of therapeutic supplements, owing to their versatile biological applications accompanied with less or no side effects to normal ...
Abid Ali Sheikh, Zahoor Ahmad Wani, Aabid Manzoor Shah, Qazi Parvaiz Hassan, Dilip Manikrao Mondhe, Mahendra Kumar Verma   +5 more
doaj   +1 more source

Thyroiditis in Rats Injected Subcutaneously with 3-Methylcholanthrene

Experimental Biology and Medicine, 1968
SummaryBuffalo strain rats were given a single s.c. injection of 4 mg of MCA in corn oil. Thyroiditis was observed in 10 of 13 females and 3 of 14 males. The glands were larger in the females. The thyroiditis could not be correlated with the presence of s.c. tumors.
M D, Reuber, E L, Glover
openaire   +2 more sources

Comparative Effect of African Walnut Oil and Docosahexaenoic Acid on Hematological and Oxidative Stress Markers of Female Wistar Rats With 7,12‐Dimethylbenz[a]anthracene‐Induced Breast Cancer

Food Science &Nutrition, Volume 14, Issue 5, May 2026.
African walnut oil and docosahexaenoic acid administration to female Wistar rats with DMBA‐induced breast cancer may delay tumor growth, increase white blood cells, platelets and mean corpuscular hemoglobin counts in the blood. DMBA significantly lowers red blood cells, hemoglobin levels, and protein concentration.
Fabrice Tonfack Djikeng, Carister Nchangnwi, Jean Paul Chedjou, Hilaire Macaire Womeni   +3 more
wiley   +1 more source

Streptonigrin Inhibition of 3-Methylcholanthrene Transformation in Vitro

Experimental Biology and Medicine, 1974
SummaryAt a nontoxic dose, the antiviral antibiotic streptonigrin protected Fischer rat embryo cells grown in vitro from transformation by 3-methylcholanthrene.
P J, Price, W A, Suk, G J, Spahn, M A, Chirigos, J A, Lane, R J, Huebner   +5 more
openaire   +2 more sources

Nonclassical MHC‐I Molecules: Emerging Therapeutic Targets in Next‐Generation Immunotherapy

MedComm, Volume 7, Issue 5, May 2026.
Immunotherapies dependent on classical MHC‐I molecules face significant challenges, including extreme polymorphism and frequent downregulation in pathological conditions. This review discusses how nonclassical MHC‐I molecules (HLA‐E, HLA‐F, HLA‐G, CD1, MR1) may potentially circumvent these limitations through restricted genetic diversity, stable ...
Wanlin He, Andrew J. McMichael
wiley   +1 more source

Water Carcinogenicity and Prevalence of HPV Infection in Esophageal Cancer Patients in Huaihe River Basin, China

Gastroenterology Research and Practice, 2018
Objective. The incidence of the upper gastrointestinal tumor has increased rapidly during recent decades. The relationship between local water pollution and the tumor is still not much clear, so this study was conducted to further investigate the local ...
Maliha Ghaffar, Jintao Li, Lei Zhang, Sara Khodahemmati, Minglian Wang, Yangjunqi Wang, Lijiao Zhao, Runqing Jia, Su Chen, Yi Zeng   +9 more
doaj   +1 more source