Results 11 to 20 of about 2,717 (170)
3-Aryl-2H-azirines as annulation reagents in the Ni(II)-catalyzed synthesis of 1H-benzo[4,5]thieno[3,2-b]pyrroles [PDF]
Beilstein Journal of Organic ChemistryA high-yielding method for the synthesis of 3-arylbenzo[4,5]thieno[3,2-b]pyrroles has been developed via pyrrole ring annulation to the aromatic benzo[b]thiophene system, using 3-arylazirines as a N‒C=C synthon.
Julia I. Pavlenko +5 more
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Untargeted metabolomics analysis of the spleens of ducks infected with Clostridium perfringens type A [PDF]
BMC Veterinary ResearchBackground The aim of this study was to investigate the metabolomic changes in the spleens of ducks artificially infected with Clostridium perfringens type A. Twenty-four healthy ducks aged 1 d were used for this purpose.
Chengrong Zeng +4 more
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Exploring the biological impact of bacteria-derived indole compounds on human cell health: Cytotoxicity and cell proliferation across six cell lines [PDF]
Toxicology ReportsOver the past two decades, research has increasingly focused on the interactions between diet, gut microbiota, and host organisms. Recent evidence suggests that tryptophan, an essential amino acid, can be metabolized by gut microbiota into indoles, which
Alisha Janiga-MacNelly +4 more
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EFFECTS OF 3‐METHYLINDOLE IN CATTLE [PDF]
British Journal of Pharmacology, 1977 Rapid intravenous injection of 3‐methylindole (3‐MI) was shown to induce an anaphylactoid‐like reaction in calves. This was suggested by the reduction in response to a repeat dose of 3‐MI, by the reduction of effects in the presence of antagonists to the putative mediators of anaphylaxis in cattle and by the production of signs similar to those seen ...
G, Atkinson +3 more
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Antibiofilm and Antivirulence Properties of Indoles Against Serratia marcescens
Frontiers in Microbiology, 2020 Indole and its derivatives have been shown to interfere with the quorum sensing (QS) systems of a wide range of bacterial pathogens. While indole has been previously shown to inhibit QS in Serratia marcescens, the effects of various indole derivatives on
Sivasamy Sethupathy +4 more
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Spectrophotometric study of the protonation processes of some indole derivatives in sulfuric acid [PDF]
Journal of the Serbian Chemical Society, 1999 The protonation of 3-methylindole, D-tryptophan, 3-formylindole, 3-acetylindole and indolyl-2-carboxylic acid in sulfuric acid media was studied by UV spectro-scopy.
GORAN M. STOJKOVIC +1 more
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Influence of 3-acetyl-5-hydroxy-2-methylindole on glioma cell proliferation and metabolism
Журнал Белорусского государственного университета: Химия, 2022 A 3-acetyl analogue of 5-hydroxyindole was synthesised and evaluated for its effects on rat C6 glioma cell functions. It was found that 3-acetyl-5-hydroxy-2-methylindole at 10 μmol/L led to a sharp reduction of mitochondrial membrane potential, induction
Jan U. Panada +8 more
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SYNTHESIS OF NEW ACTIVATED INDOLES; 3-(4’-BROMOPHENYL)-4,6-DIMETHOXY-2-METHYLINDOLE
Indonesian Journal of Chemistry, 2010 3-(4'-Bromophenyl)-4,6-dimethoxy-2-methylindole has been synthesized from 4,6-dimethoxyaniline via the modified Bischler method. Reaction of 4,6-dimethoxyaniline with 2,4-dibromopropiophenone gave an aniline ketone in 85%, and then it was protected to ...
Tutik Dwi Wahyuningsih
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Pharmaceuticals, 2015 Seven novel N-arylsulfonyl-3-(2-yl-ethanone)-6-methylindole derivatives 4a–f and 6 were readily synthesized and have been identified as inhibitors of human immunodeficiency virus type-1 (HIV-1) replication. Initial biological studies indicated that among
Zhiping Che +5 more
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Molecules, 2022 A new synthetic alternative to the synthesis of 3-methyl indoles and 3-methyl indoline-2-ols with an excellent atomic economy is presented in this study.
Frank Hochberger-Roa +6 more
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