Results 21 to 30 of about 2,717 (170)

Indole analogues decreasing the virulence of Vibrio campbellii towards brine shrimp larvae

Microbial Biotechnology, 2022
Indole signalling has been proposed as a potential target for the development of novel virulence inhibitors to control bacterial infections. However, the major structural features of indole analogues that govern antivirulence activity remain unexplored ...
Shanshan Zhang, Qian Yang, Tom Defoirdt
doaj   +1 more source

Indole ring oxidation by activated leukocytes prevents the production of hypochlorous acid

Brazilian Journal of Medical and Biological Research, 2005
Hypochlorous acid (HOCl) released by activated leukocytes has been implicated in the tissue damage that characterizes chronic inflammatory diseases. In this investigation, 14 indole derivatives, including metabolites such as melatonin, tryptophan and ...
V.F. Ximenes, I.M.M. Paino, O.M.M. de Faria-Oliveira, L.M. da Fonseca, I.L. Brunetti   +4 more
doaj   +1 more source

Deprotonative C(sp³)/C(sp²)-H (Multi)Silylation of (Hetero)Arenes Mediated by NaTMP. [PDF]

Angew Chem Int Ed Engl
An operationally simple protocol using a strongly basic sodium amide in combination with sterically emcumbered silicon electrophiles enables the deprotonative C–H (multi)silylation of a myriad of (hetero)arenes. Mechanistic investigations highlight the pivotal role of steric and coordination effects in controlling the regioselectivity and efficiency of
Sánchez-Roa D, Belrhomari S, McGinley A, Liju CA, Mu M, García-Melchor M, Hevia E.   +6 more
europepmc   +2 more sources

Biotransformation of Indole to 3-Methylindole by Lysinibacillus xylanilyticus Strain MA

Journal of Chemistry, 2015
An indole-biotransforming strain MA was identified as Lysinibacillus xylanilyticus on the basis of the 16S rRNA gene sequencing. It transforms indole completely from the broth culture in the presence of an additional carbon source (i.e., sodium succinate)
Pankaj Kumar Arora, Kartik Dhar, Rafael Alejandro Veloz García, Ashutosh Sharma   +3 more
doaj   +1 more source

An odorant receptor from Anopheles sinensis in China is sensitive to oviposition attractants

Malaria Journal, 2018
Background Anopheles sinensis is an important vector for the spread of malaria in China. Olfactory-related behaviours, particularly oviposition site seeking, offer opportunities for disrupting the disease-transmission process.
Hongmei Liu, Luhong Liu, Peng Cheng, Xiaodan Huang, Maoqing Gong   +4 more
doaj   +1 more source

Microbial Degradation of Indole and Its Derivatives

Journal of Chemistry, 2015
Indole and its derivatives, including 3-methylindole and 4-chloroindole, are environmental pollutants that are present worldwide. Microbial degradation of indole and its derivatives can occur in several aerobic and anaerobic pathways; these pathways ...
Pankaj Kumar Arora, Ashutosh Sharma, Hanhong Bae   +2 more
doaj   +1 more source

Efficient One-Pot Synthesis of Indol-3-yl-Glycines via Uncatalyzed Friedel-Crafts Reaction in Water

Molecules, 2009
The three component reaction of primary aliphatic amines, glyoxalic acid and indole or N-methylindole in water at ambient temperature affords indol-3-yl or N-methylindol-3-yl-glycine in almost quantitative yields.
Mehdi Ghandi, Abuzar Taheri
doaj   +1 more source

Mass spectrometric analysis of bioactive conditioned media of bacteria isolated from reptilian gut

Future Science OA, 2023
Aim: To determine whether selected gut bacteria of crocodile exhibit antibacterial properties. Materials & methods: Two bacteria isolated from Crocodylus porosus gut were used, namely: Pseudomonas aeruginosa and Aeromonas dhakensis.
Ruqaiyyah Siddiqui, Noor Akbar, Nelson Cruz Soares, Hamza Mohammad Al-Hroub, Mohammad Harb Semreen, Sutherland K Maciver, Naveed Ahmed Khan   +6 more
doaj   +1 more source

Coordination‐Driven Direct C─H Metalation of N‐Heterocycles With a Superbasic Co(II) Amide Co(TMP)2

Angewandte Chemie, Volume 138, Issue 34, 17 August 2026.
By enabling regioselectivities that are inaccessible with conventional bases, this study introduces a Co(II) amide platform for the deprotonative C─H metalation of sensitive N‐heterocycles. Subsequent interception of the resulting Co(II) intermediates with external oxidants affords a family of sterically congested, TMP‐substituted heterocycles via C─N ...
Na Jin, Manting Mu, Max García‐Melchor, Eva Hevia   +3 more
wiley   +2 more sources

Reduced concentration of androstenone and upregulation of 3β-hydroxysteroid dehydrogenase and 17β-hydroxysteroid dehydrogenase mRNA levels by active immunisation against gonadotropin releasing hormone I

Italian Journal of Animal Science, 2014
The aim of this study was to investigate the efficacy of active immunisation against recombinant maltose binding protein-gonadotropin releasing hormone I (MBP-GnRH-I6) in preventing boar taint.
Ya Liu, Fugui Fang, Shudong Jiang, Yuan Tian, Lei Luo, Min Song, Shiping Su, Yong Pu, Jie Zhou, Xiaorong Zhang   +9 more
doaj   +1 more source