Results 181 to 190 of about 13,314,497 (296)

Triazole-Functionalized Jatrophone Derivatives as Antiprotozoal Agents Against <i>Trypanosoma cruzi</i>: Synthesis, Biological Evaluation and Structure-Activity Relationships. [PDF]

Pharmaceuticals (Basel)
Pertino MW, Carreño Gonzalez P, Venegas González C, Schmeda-Hirschmann G, Vega Gómez C, Rolón M, Rojas de Arias A.   +6 more
europepmc   +1 more source

Amino acid vectorization of salicylic acid enables efficient activation of NPR1‐dependent defense without phytotoxicity

Pest Management Science, EarlyView.
Amino acid‐vectorized salicylic acid activates PR1/NPR1‐dependent defenses without phytotoxicity, showing an efficient strategy for controlled delivery and enhanced plant immunity. Abstract BACKGROUND Addressing global food security under rapid population growth and climate change requires sustainable strategies to protect crops from pathogens while ...
Ruth Oussou, Benoit Guichard, Loïc Lemée, Vincent Lebeurre, Cécile Marivingt‐Mounir, Jean‐François Chollet, Sylvain La Camera   +6 more
wiley   +1 more source

[Retracted] Novel triazole analogs of apigenin-7-methyl ether exhibit potent antitumor activity against ovarian carcinoma cells via the induction of mitochondrial-mediated apoptosis. [PDF]

Exp Ther Med
Qi Y, Ding Z, Yao Y, Ma D, Ren F, Yang H, Chen A.   +6 more
europepmc   +1 more source

The continuing significance of chiral agrochemicals

Pest Management Science, Volume 81, Issue 4, Page 1697-1716, April 2025.
In the time frame 2018–2023, around 43% of the 35 chiral agrochemicals introduced to the market (herbicides, fungicides, insecticides, acaricides, and nematicides) contain one or more stereogenic centers in the molecule, and almost 69% of them have been marketed as racemic mixtures of enantiomers or stereoisomers.
Peter Jeschke
wiley   +1 more source

Biological and In Silico Evaluation of Novel Methoxyphenol-1,2,3-Triazole Hybrids as Multifunctional Anti-Alzheimer's and Anticancer Agents. [PDF]

Chem Biol Drug Des
Onur S, Çeşme M, Tümer F.
europepmc   +1 more source

Natural Products as Modulators of ABC Transporters in Breast Cancer

Phytotherapy Research, EarlyView.
ABSTRACT Breast cancer remains a significant global health challenge, with high incidence and mortality rates despite advancements in early detection and treatment. Multidrug resistance (MDR), particularly in aggressive subtypes like triple‐negative breast cancer (TNBC), continues to hinder effective therapy.
Yoganishalini Sagadevan, Reyhaneh Farghadani, Ammu K. Radhakrishnan   +2 more
wiley   +1 more source

Prevalence of cyp51A variants in a US collection of Aspergillus fumigatus clinical isolates and comparative analysis of their contribution to triazole antifungal resistance. [PDF]

J Antimicrob Chemother
Gómez Londoño LF, Souza ACO, Burt B, Das S, Ge W, Meza-Perez V, Wiederhold NP, Shelat AA, Cuomo CA, Fortwendel JR, Rogers PD.   +10 more
europepmc   +1 more source

Combining Laser‐Induced Edition to Collision‐Induced Sequencing of Digital Oligomers in a Single Gas‐Phase Experiment

Rapid Communications in Mass Spectrometry, EarlyView.
ABSTRACT Rationale To increase the confidentiality level of molecular tags, binary information can be hidden in sequence‐defined oligomers using isobaric monomers including a photo‐sensitive one, which mass can be modified upon light irradiation. Reading such secured data requires light edition prior to MS/MS sequencing, which was investigated here in ...
Clothilde Comby‐Zerbino, Jean‐François Lutz, Luke MacAleese, Laurence Charles   +3 more
wiley   +1 more source

Multifunctional Nanodiamond Conjugate With a Tumor‐Specific EGFR‐Targeting Peptide and Photoactivated CO Release for Improved Therapeutic Efficacy in Head and Neck Cancers

Small, EarlyView.
A multifunctional nanodiamond conjugate carrying a blue light‐activated carbon monoxide‐releasing molecule and an EGFR‐targeting peptide enables efficient, targeted CO delivery in vitro and in vivo. Upon photoactivation, the particles induce cancer‐specific cytotoxicity and significantly suppress tumor growth and lymph node metastasis in a head and ...
Harsh Nitin Dongre, Elisabeth Mayerhoefer, Julia Puck, Himalaya Parajuli, Lorena Larios Salazar, Paul Johan Høl, Ridhima Das, Patrick Roth, Christian Arvei Moen, Ulrich Schatzschneider, Line Bjørge, Daniela Elena Costea, Anke Krueger   +12 more
wiley   +1 more source

Imaging of Fibroblast Activation Protein in the Microenvironment of Tumors by ¹⁸F‑Labeled Positron Emission Tomography Tracers with Increased Polarity. [PDF]

ACS Pharmacol Transl Sci
Köchel R, Wagner S, Breyholz HJ, Schäfers M, Schwegmann K, Wünsch B.   +5 more
europepmc   +1 more source