Results 201 to 210 of about 13,314,497 (296)

Recent Advances in Benzimidazole-Triazole Hybrids for Single- and Multi-Target Protein Kinase Inhibition. [PDF]

Pharmaceuticals (Basel)
Abu Al Rub HM, Eissa AG.
europepmc   +1 more source

Evolution of Dermatophytic Fungi: Anthropogenic and Biogenic Environmental Factors

International Journal of Dermatology, EarlyView.
ABSTRACT Climate change presents new challenges to dermatologic care, ranging from anthropogenic factors, such as pollution that select for extremotolerant and potentially antifungal‐resistant fungi, to biogenic factors that can drive zoonotic outbreaks, which have received increased attention since the SARS‐CoV‐2 pandemic.
Aditya K. Gupta, Tong Wang, Richard C. Summerbell   +2 more
wiley   +1 more source

Triazole 187 is a biased KOR agonist that suppresses itch without sedation and induces anxiolytic-like behaviors in mice. [PDF]

Neuropsychopharmacology
Volf A, Brust TF, Kobylski RR, Czekner KM, Stahl EL, Cameron MD, Trojniak AE, Wood AB, Aubé J, Bohn LM.   +9 more
europepmc   +1 more source

Deep and disseminated dermatophytosis in immunocompromised populations—A systematic review

Journal of the European Academy of Dermatology and Venereology, EarlyView.
Dermatophyte infections of the dermis and subcutaneous tissue (i.e. deep dermatophytosis)—associated with secondary complications including pseudomycetoma and systemic dissemination—affect vulnerable populations with primary or acquired immunodeficiencies.
Aditya K. Gupta, Tong Wang, Susmita, Ditte Marie L. Saunte, Roderick Hay, Vincent Piguet   +5 more
wiley   +1 more source

Arabidopsis inositol polyphosphate kinase activities regulate COP9 deneddylation functions in phosphate homeostasis

Journal of Integrative Plant Biology, EarlyView.
Plant phosphate (Pi) homeostasis relies on coordinated activities of the inositol polyphosphate kinases IPK1 and ITPK1, which balance localized InsP7 biosynthesis to control COP9 signalosome (CSN)‐dependent deneddylation of cullin 1 (CUL1). Perturbation of this equilibrium affects the stability of SPX4, a key negative regulator of phosphate starvation ...
Yashika Walia, Medha Noopur, Ishana Bhattacharya, Bhaskar Chandra Sahoo, Mritunjay Kasera, Naga Jyothi Pullagurla, Smritikana Dutta, Guizhen Liu, Gabriel Schaaf, Henning Jessen, Debabrata Laha, Souvik Bhattacharjee, Saikat Bhattacharjee   +12 more
wiley   +1 more source

Development of new quinoline-triazole based hybrids: synthesis, nano-encapsulation, DFT calculations, and evaluation of antidiabetic and antioxidant activity. [PDF]

RSC Adv
Elhalmoushy FM, Abd Al Moaty MN, Hegazy AS, Soliman SM, Sherif M, Ghareeb DA, Hagar M, Fouad MA.   +7 more
europepmc   +1 more source

A cytochrome P450 gene, GmSUR2a, confers submergence tolerance and improves yield in soybean by modulating auxin homeostasis

Journal of Integrative Plant Biology, EarlyView.
The key cytochrome P450 gene GmSUR2a enables soybeans to withstand destructive submergence stress. By lowering the level of the plant hormone indole‐3‐acetic acid, this gene improves soybean survival and increases field yield. It offers an important tool for breeding stress‑resilient soybeans, securing food production against extreme weather conditions.
Yangyang Chen, Pingzhang Feng, Mengwei Zheng, Lipei Zhao, Yi Li, Yali Jing, Yisa Wang, Bo Zhang, Changzhong Liu, Chengyu Wei, Jijun Yan, Jinfang Chu, Shanshan Chu, Erhui Xiong, Yongqing Jiao   +14 more
wiley   +1 more source

Retraction: Ph-triazole as a therapeutic agent for pancreatic cancer: Synthesis, in silico, and in vitro evaluation. [PDF]

PLoS One
PLOS One Editors.
europepmc   +1 more source

Platelet‐Rich Fibrins as Local Drug‐Delivery Carriers

Journal of Periodontal Research, EarlyView.
Autologous platelet concentrates (APCs), particularly platelet‐rich fibrin (PRF), act as biologically active fibrin scaffolds, capable of entrapping and gradually releasing therapeutic agents in oral and periodontal therapy. The incorporation of bioactive compounds, such as antibiotics, antifungals, vitamins, antidiabetic drugs, and exosomes, enhances ...
Karim M. Fawzy El‐Sayed, Christof E. Dörfer   +1 more
wiley   +1 more source

Multicomponent synthesis of 2<i>H</i>-chromene-fused-thiazolo-triazole derivatives <i>via</i> cascade Michael addition/cyclization reaction: anticancer, antibacterial and computational evaluations. [PDF]

RSC Adv
Samanta B, Pati T, Dash A, Panda BS, Naik E, Mohapatra S, Sahoo CR, Naik PK.   +7 more
europepmc   +1 more source