Results 211 to 220 of about 47,847 (251)

Anti-proliferative effects of novel hybrids of 1, 2, 3-triazole-pyrimidines, 1, 2, 3–triazole–benzimidazoles and 1, 2, 3-triazole-coumarins

2015
The series of novel hybrids including: 1, 2, 3-triazole-pyrimidines, 1, 2, 3-triazole-coumarins and 1, 2, 3-triazole benzimidazoles were evaluated for their anti-proliferative activity against five human cancer cell lines and normal embryo mouse fibroblasts. Among these, TG-16 (C16H12ClN5 ; IC50=4, 83µM), TG-14 (C22H15BrF2N8O2 ; IC50=4, 53µM) and TG-15
Sedić, Mirela, Kraljević Pavelić, Sandra, Raić-Malić, Silvana, Tomljenović Paravić, Andrea   +3 more
openaire   +1 more source

Ring‐degenerate rearrangement of 5‐amino‐4‐iminomethyl‐1, 2, 3‐triazoles

Journal of Heterocyclic Chemistry, 1989
Abstract5‐Amino‐4‐(substituted)iminomethyl‐1‐phenyl‐1, 2, 3‐triazoles 5 rearrange thermally to 4‐amidino‐substituted triazoles 6 instead of undergoing the Dimroth rearrangement to 5‐anilinotriazoles 3.
Gerrit L'Abbé, Anna Vandendriessche
openaire   +1 more source

PHARMACOPHORE-BASED HYBRIDS OF NUCLEOSIDES AND 1, 2, 3-TRIAZOLES

2015
Nucleoside analogs have acquired an important role as therapeutic agents in the field of chemotherapy on account of their extensive biological activities. Introduction of a triazole ring into nucleosides to improve their bioactivity for antitumor or antiviral applications has become wide spread in drug design practices.1, 2 The 1, 2, 3-triazole unit ...
openaire   +1 more source

Combination of 1,2,3-triazole and 1,2,4-triazole frameworks for new high-energy and low-sensitivity compounds

Energetic Materials Frontiers, 2021
Hongwei Yang
exaly  

Synthesis and antiproliferative activity of the novel 1, 2, 3-triazole coumarin and quinoline derivatives

2018
1, 2, 3-triazole ring has a great role as pharmacophore which is responsible for antitumor and antimicrobial activity. It is introduced in many drugs due to moderate dipole properties, rigid structure and stability in vivo. Besides, 1, 2, 3-triazoles have attracted considerable attention in recent years because of their wide range of biological ...
Gazivoda Kraljević, Tatjana, Raić-Malić, Silvana, Sokol, Ivana   +2 more
openaire   +2 more sources

781. The tautomerism of 5-amino-1-aryl-1 : 2 : 3-triazoles

Journal of the Chemical Society (Resumed), 1953
B. R. Brown, D. Ll. Hammick, S. G. Heritage   +2 more
openaire   +1 more source

Design and synthesis of harmine and coumarin/quinoline hybrids bridged with 1, 2, 3-triazole

2019
Malaria, one of the neglected tropical diseases, is responsible for more than 430000 deaths and 210 million new cases annually. The cause of malaria, protozoal parasite of the genus Plasmodium, is developing resistance to the known drugs, which drives the need for the discovery and development of new antimalarials.
Perković, Ivana, Raić-Malić, Silvana, Rajić, Zrinka   +2 more
openaire  

Study on 1, 2, 3-Triazole-Containing Quinolines: Promising Pharmacological Hybrid Agents

2022
Leonor Y. Vargas-Méndez, Vladimir V. Kouznetsov   +1 more
openaire   +1 more source

Catalysis by 1,2,3-triazole- and related transition-metal complexes

Coordination Chemistry Reviews, 2014
Didier Astruc, Pengxiang Zhao, Deshun Huang   +2 more
exaly  

CCCXXXVIII.—2 : 5-Iminodihydro-1 : 2 : 3-triazole. Part II

J. Chem. Soc., Trans., 1924
Helen Winifred Carnelley, Pavitra Kumar Dutt   +1 more
openaire   +1 more source