Results 231 to 240 of about 405,626 (326)

Pan-3C Protease Inhibitor Rupintrivir Binds SARS-CoV-2 Main Protease in a Unique Binding Mode. [PDF]

Biochemistry, 2021
Lockbaum GJ, Henes M, Lee JM, Timm J, Nalivaika EA, Thompson PR, Kurt Yilmaz N, Schiffer CA.   +7 more
europepmc   +1 more source

Targeting the tumor-promoting microenvironment in MET-amplified NSCLC cells with a novel inhibitor of pro-HGF activation [PDF]

, 2017
Galemmo, Robert A, Jr, Han, Zhenfu, Janetka, James W, Klampfer, Lidija, Owusu, Benjamin Y, Thomas, Shantasia, Venukadasula, Phanindra   +6 more
core   +2 more sources

Zinc‐Containing Bioactive Glass Programs Macrophage Polarization through Extracellular Traps Regulation for Enhanced Diabetic Wound Healing

Advanced Healthcare Materials, EarlyView.
Zinc‐containing bioactive glass (ZnBG) promotes diabetic wound healing by regulating macrophage extracellular traps (METs). Specifically, ZnBG reduces oxidative stress and inhibits the PAD4 and NLRP3/caspase‐1/GSDMD signaling pathways, thereby suppressing MET formation.
RuiYang Sun, XueBo Wei, ZhuoYang Song, JunJun Luo, JingYi Ye, YinNan Zhang, LiFei Zhu, Jie Gao, Hongyu Zhang, Hong Zhu, Xin Wang, Ke Xu   +11 more
wiley   +1 more source

Peptidomimetic ethyl propenoate covalent inhibitors of the enterovirus 71 3C protease: a P2–P4 study

, 2015
Melgious J. Y. Ang, Qiu Ying Lau, Fui Mee Ng, Siew Wen Then, Anders Poulsen, Yuen Kuen Cheong, Zi Xian Ngoh, Yong Wah Tan, Jianhe Peng, Thomas H. Keller, Jeffrey Hill, Justin J. H. Chu, C. S. Brian Chia   +12 more
openalex  

Determinants of the VP1/2A junction cleavage by the 3C protease in foot-and-mouth disease virus-infected cells

, 2016
Thea Kristensen, Preben Normann, Maria Gullberg, Ulrik Fahnøe, Charlotta Polacek, Thomas Bruun Rasmussen, Graham J. Belsham   +6 more
openalex   +1 more source

The inhibitory effects of PGG and EGCG against the SARS-CoV-2 3C-like protease

, 2021
Wei-Chung Chiou, Jui‐Chieh Chen, Yun‐Ti Chen, Jinn‐Moon Yang, Lih‐Hwa Hwang, Yi-Shuan Lyu, H. Yang, Cheng Huang   +7 more
openalex   +2 more sources

Seneca Valley virus 3C protease cleaves HDAC4 to antagonize type I interferon signaling. [PDF]

J Virol
Li Z, Yang J, Ma R, Xie S, Wang D, Quan R, Wen X, Liu J, Song J.   +8 more
europepmc   +1 more source

Porcine Picornavirus 3C Protease Degrades PRDX6 to Impair PRDX6-mediated Antiviral Function. [PDF]

Virol Sin, 2021
Wang C, Feng H, Zhang X, Li K, Yang F, Cao W, Liu H, Gao L, Xue Z, Liu X, Zhu Z, Zheng H.   +11 more
europepmc   +1 more source

Packed for Ossification: High‐Density Bioprinting of hPDC Spheroids in HAMA Toward Endochondral Ossification

Advanced Healthcare Materials, EarlyView.
Human periosteum‐derived cell spheroids bioprinted at high density within a hyaluronic acid matrix promote fusion and hypertrophic cartilage formation in vitro. Early encapsulation enhances spheroid interaction and matrix maturation, generating scalable cartilage templates intended for endochondral bone regeneration.
Ane Albillos Sanchez, Maria Paula Marks, Paula Casademunt, Adrián Seijas‐Gamardo, Ioannis Papantoniou, Lorenzo Moroni, Carlos Mota   +6 more
wiley   +1 more source

3D Soft Hydrogels Induce Human Mesenchymal Stem Cells “Deep” Quiescence

Advanced Healthcare Materials, EarlyView.
Three‐dimensional soft hydrogels mimicking the bone marrow niche induce deep quiescence in human mesenchymal stem cells. Unlike 2D culture, 3D matrices halt proliferation, regulate cell‐cycle and quiescence markers, and downregulate mTORC1 signaling, preserving stem cell phenotype and therapeutic potential ex vivo.
David Boaventura Gomes, Timo Rademakers, Ana Filipa Henriques Lourenço, Andrea Calore, Clarissa Tomasina, Denis van Beurden, Jinjie Venema, Bryan Chömpff, Hong Liu, Nicole Bouvy, Sandra Camarero‐Espinosa, Lorenzo Moroni   +11 more
wiley   +1 more source