Results 101 to 110 of about 10,804,267 (253)
3D lens-free time-lapse microscopy for 3D cell culture
, 2017 International audienceWe propose a new imaging platform based on lens-free time-lapse microscopy for 3D cell culture and its dedicated algorithm lying on a fully 3D regularized inverse problem approach.
Thomas Bordy +15 more
core +1 more source
CellsHuman-induced pluripotent stem cells (hiPSCs) have shown great potential for human health, but their growth and properties have been significantly limited by the traditional monolayer (2D) cell culture method for more than 15 years. Three-dimensional (3D)
Muyun Cui +8 more
doaj +1 more source
Molecular Oncology, EarlyView.This study identifies somatostatin receptor 4 (Sstr4) as a critical tumor suppressor against skin and head/neck cancers (HNSCC, cSCC, and BCC). The loss of Sstr4 removes a check on cell growth, causing hyperactivation of the MAPK‐ERK signaling pathway (↑).
Ali Taqvi +6 more
wiley +1 more source
Use of Schwann cell-seeded nanofiber as nerve conduit
, 2014 Schwann cell-seeded guidance channels have been exploited to bridge and guide axonal re-growth across gaps in lesioned nerves. By orienting the Schwann cell growth on aligned nanofibers, we hypothesized that axonal growth can be guided along the ...
Tam, KW, Tung, WT, Shum, DKY, Chan, YS
core
, 2015 Surfactant production is important in maintaining alveolar function both in vivo and in vitro, but surfactant expression is the primary property lost by alveolar Type II Pneumocytes in culture and its maintenance is a functional requirement. To develop a
Ashna, U +3 more
core +1 more source
Molecular Oncology, EarlyView.We show that emergence of castration‐resistant prostate (CRPC) is associated with significant upregulation of cyclins that positively regulate cyclin‐dependent kinase 2 (CDK2) and concomitant downregulation of CDK4 cyclins. This renders CRPC cells dependent on the high activity of CDK2, and CDK2 inhibitors synergistically sensitize CRPC cells to both ...
Joyeeta Chatterjee +3 more
wiley +1 more source
Defining a 3-dimensional (3D) in vitro model to study immune cell and renal cell interactions [PDF]
, 2015 This study aimed to develop a 3-Dimensional (D) hydrogel system for the co-culture of autologous human renal and immune cells. Previous studies have shown that human renal epithelial cells are able to modulate autologous immune cell responses.
Afrin, Sadia
core
3D+time acquisitions of 3D cell culture by means of lens-free tomographic microscopy
, 2018 Editors: Thomas G. Brown, Carol J. Cogswell, Tony WilsonInternational audienceWe propose a three-dimensional (3D) imaging platform based on lens-free microscopy to perform multi-angle acquisitions on 3D cell cultures embedded in extracellular matrix (ECM)
Thomas Bordy +13 more
core +1 more source
Molecular Oncology, EarlyView.Loss of eIF5A rewires thapsigargin‐mediated endoplasmic reticulum stress responses in multiple myeloma cells by selective translation of mRNA transcripts, consequently dampening thapsigargin‐induced unfolded protein response (UPR) activation and shifting the balance from induction of apoptosis toward cell survival and proliferation.
Demi Both +7 more
wiley +1 more source
Cell-to-cell marker protein expression in the 2D and 3D cell culture environment.
, 2019 (A), (B) Induction of release of the epithelial-mesenchymal transition (EMT) mechanism protein in bladder cancer cells treated with TGF-β1. After 72 h, the supernatant of the 5637 and T24 bladder cancer cell culture media was separated, and e-cadherin ...
Byung Hoon Chi (3175194) +5 more
core +1 more source