Results 91 to 100 of about 8,821,447 (199)

Visualization of chromosomal reorganization induced by heterologous fusions in the mammalian nucleus

Nature Communications
Chromosomes are spatially organized and functionally folded into a specific macro-structure in the nucleus. Recently, we and others created haploid cells with chromosome fusions.
Meng Yan, Xiaoyu Merlin Zhang, Zhenhua Yang, Miao Jia, Rongyu Liao, Jinsong Li   +5 more
doaj   +1 more source

Effects of aneuploidy on genome structure, expression, and interphase organization in Arabidopsis thaliana.

PLoS Genetics, 2008
Aneuploidy refers to losses and/or gains of individual chromosomes from the normal chromosome set. The resulting gene dosage imbalance has a noticeable affect on the phenotype, as illustrated by aneuploid syndromes, including Down syndrome in humans, and
Bruno Huettel, David P Kreil, Marjori Matzke, Antonius J M Matzke   +3 more
doaj   +1 more source

aLTAG3D, un logiciel pour l'archivage 3D

, 2020
" aLTAG3D est un logiciel libre offrant une interface utilisateur simple et efficace pour la génération d'archive à long terme de projets 3D. L'archive générée est immédiatement compatible avec les services du CINES
Consortium 3D SHS Team
core  

Modeling meiotic chromosomes indicates a size dependent contribution of telomere clustering and chromosome rigidity to homologue juxtaposition [PDF]

, 2012
Meiosis is the cell division that halves the genetic component of diploid cells to form gametes or spores. To achieve this, meiotic cells undergo a radical spatial reorganisation of chromosomes.
Penfold, Christopher A., Paul E Brown, Paul E. Brown (168021), Alastair S H Goldman, Christopher A. Penfold (168015), Neil D. Lawrence (168025), Penfold, C.A., Christopher A Penfold, Lawrence, Neil (Neil D.), Lawrence, N.D., Lawrence Neil D., Goldman Alastair S. H., Goldman, Alastair S. H., Alastair S. H. Goldman (168028), Brown Paul E., Neil D Lawrence, Penfold Christopher A., Brown, Paul E., Brown, P.E., Goldman, A.S.H.   +19 more
core   +2 more sources

L’archivage pérenne des modèles numériques 3D pour les SHS

, 2020
Ce document est la formalisation d’une étape de la réflexion consacrée à l'archivage des données 3D mené au sein du consortium 3D SHS en collaboration avec Huma-Num et le CINES.
Consortium 3D SHS Team
core  

Inferring the three-dimensional structures of the X-chromosome during X-inactivation

, 2019
The Hi-C experiment can capture the genome-wide spatial proximities of the DNA, based on which it is possible to computationally reconstruct the three-dimensional (3D) structures of chromosomes.
Sun, Jonathan Z, Zhu, Hao, Wang, Zheng, Pandey, Ras B, Wang, Nan   +4 more
core   +1 more source

Réaliser un projet de modèles numériques 3D pour le patrimoine. Guide de rédaction d'un cahier des charges

, 2020
"Dans le cadre des activités du Consortium 3D de la TGIR Huma-Num, de nombreuses rencontres ont eu lieu réunissant des spécialistes aux profils divers (historiens, archéologues, informaticiens, architectes, ingénieurs 3D, archivistes …etc.) afin de ...
Consortium 3D SHS Team
core  

Xist recruits the X chromosome to the nuclear lamina to enable chromosome-wide silencing

, 2016
The Xist long noncoding RNA orchestrates X chromosome inactivation, a process that entails chromosome-wide silencing and remodeling of the three-dimensional (3D) structure of the X chromosome.
Chen CK, Blanco M, Aznauryan E, Ollikainen N, Jackson C, Chow A, Surka C, Cerase A, McDonel P, Guttman M   +9 more
core  

Structure of the chromosome.

, 2016
Structure of the chromosome.
Yueke Wang (3095586), Jianyun Chen (725586), Yinyin Tang (3219852), Xianbin Li (401049)   +3 more
core   +1 more source

Inference of 3D structure of diploid chromosomes

, 2018
The spatial organization of DNA in the cell nucleus plays an important role for gene regulation, DNA replication, and genomic integrity. Through the development of chromosome capture experiments (such as 3C, 4C, Hi-C) it is now possible to obtain the contact frequencies of the DNA at the whole-genome level.
openaire   +1 more source