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The CENP-A chaperone complex spatially organizes centromeres. [PDF]

open access: yesSci Adv
Gupta H   +9 more
europepmc   +1 more source

Comparative Analysis of Triticeae Satellite Repeats Using Low-Coverage Sequencing, qPCR, and FISH. [PDF]

open access: yesInt J Mol Sci
Yurkina AI   +5 more
europepmc   +1 more source
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Towards Recovery of 3D Chromosome Structure

2004 Conference on Computer Vision and Pattern Recognition Workshop, 2005
The objectives of this work include automatic recovery and visualization of a 3D chromosome structure from a sequence of 2D tomographic reconstruction images taken through the nucleus of a cell. Structure is very important for biologists as it affects chromosome functions, behavior of the cell and its state.
Sabarish V. Babu   +3 more
openaire   +2 more sources

The 3D structure of human chromosomes in cell nuclei

Chromosome Research, 2002
The spatial arrangement of some genetic elements relative to chromosome territories and in parallel with the cell nucleus was investigated in human lymphocytes. The structure of the chromosome territories was studied in chromosomes containing regions (clusters) of highly expressed genes (HSA 9, 17) and those without such clusters (HSA 8, 13).
E, Lukásová   +4 more
openaire   +2 more sources

Techniques for and challenges in reconstructing 3D genome structures from 2D chromosome conformation capture data

Current Opinion in Cell Biology, 2023
Chromosome conformation capture technologies that provide frequency information for contacts between genomic regions have been crucial for increasing our understanding of genome folding and regulation. However, such data do not provide direct evidence of the spatial 3D organization of chromatin.
Zilong Li   +2 more
openaire   +2 more sources

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