Results 71 to 80 of about 2,672,261 (295)

Liver organoids: modelling complexity in homeostasis and disease

open access: yesFEBS Letters, EarlyView.
Studying liver in vitro has been challenging because simple 2D cell cultures fail to capture liver's cellular and architectural complexity. To bridge this gap, scientists increasingly use organoids, 3D liver models which better mimic liver composition and function. This review examines recent advances in liver organoid complexity and realism, discusses
Anna M. Dowbaj, Meritxell Huch
wiley   +1 more source

An independent declarative 3D audio format on the basis of XML

open access: yes, 2003
Proceedings of the 9th International Conference on Auditory Display (ICAD), Boston, MA, July 7-9, 2003.Presented at the 9th International Conference on Auditory Display (ICAD), Boston, MA, July 7-9, 2003.This paper describes the development of an XML ...
Meissner, Klaus   +2 more
core   +1 more source

Golgi enzymes are retrieved from the plasma membrane to the trans‐Golgi network

open access: yesFEBS Letters, EarlyView.
Golgi enzymes are traditionally considered resident proteins retained within the Golgi apparatus. Here, we demonstrate that a subset transiently reaches the cell surface and is subsequently retrieved to the trans‐Golgi network via retrograde transport. Using a nanobody‐based toolkit, we uncover a dynamic trafficking cycle of several Golgi enzymes.
Dominik P. Buser, Tina Junne
wiley   +1 more source

Tools for auditory display research

open access: yes, 2000
Presented of the 6th International Conference on Auditory Display (ICAD), Atlanta, GA, April 2-5, 2000Presented at the 6th International Conference on Auditory Display (ICAD), Atlanta, GA, April 2-5, 2008TDT will demonstrate its Power sDAC Convolver and ...
Wilson, Wilard   +2 more
core  

A perceptual framework for the auditory display of scientific data

open access: yes, 1994
Presented at 2nd International Conference on Auditory Display (ICAD), Santa Fe, New Mexico, November 7-9, 1994.Presented at 2nd International Conference on Auditory Display (ICAD), Santa Fe, New Mexico, November 7-9, 1994.A principal requirement of the ...
Barrass, Stephen
core   +1 more source

Ligand‐dependent transcriptional heterogeneity in cell cycle gene expression delays G1/S entry

open access: yesFEBS Letters, EarlyView.
EGF and HRG induce distinct G1/S progression programs in ErbB2‐amplified BT474 breast cancer cells. Despite activating the potent ErbB2–ErbB3 heterodimer, HRG does not accelerate cell‐cycle entry. Instead, EGF promotes earlier restriction‐point passage via ERK–FOS signaling, whereas HRG activates the AKT–MYC axis, driving transcriptional heterogeneity ...
Ririn Rahmala Febri   +5 more
wiley   +1 more source

Scaling of Three-Dimensional Computer-Generated Holograms with Layer-Based Shifted Fresnel Diffraction

open access: yesApplied Sciences, 2019
Holographic three-dimensional (3D) displays can reconstruct a whole wavefront of a 3D scene and provide rich depth information for the human eyes. Computer-generated holographic techniques offer an efficient way for reconstructing holograms without ...
Hao Zhang, Liangcai Cao, Guofan Jin
doaj   +1 more source

Emerging experimental and computational methods for studying redox‐regulated structural transitions

open access: yesFEBS Letters, EarlyView.
Redox reactions can reshape proteins and alter how they behave in cells, with important consequences for health and disease. This review explores emerging experimental and computational approaches for discovering these redox‐sensitive protein switches, revealing their structural effects, and predicting their behavior, opening new opportunities to ...
Tasneem Rass   +2 more
wiley   +1 more source

Sonification for Everyday Life: Proceedings of the 25th Annual International Conference on Auditory Display

open access: yes, 2019
Complete proceedings of the 25th International Conference on Auditory Display (ICAD2019), June 23-27, 2019, Northumbria University, Newcastle upon Tyne ...

core   +1 more source

Structures of mycobacterial 3‐methylcrotonyl‐CoA carboxylase reveal carrier‐domain translocation between catalytic sites

open access: yesFEBS Letters, EarlyView.
Mycobacterial 3‐methylcrotonyl‐CoA carboxylase uses a mobile biotin‐carrying domain to shuttle a carboxyl group between two catalytic sites, enabling carboxylation of 3‐methylcrotonyl‐CoA during leucine breakdown. Cryo‐electron microscopy captures the carrier at both sites and reveals an inward loop movement that may prevent futile rebinding to the ...
Ajit Yadav   +2 more
wiley   +1 more source

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