Results 131 to 140 of about 5,528,770 (310)

La Newsletter du CST3D

, 2023
L'équipe du Consortium 3D-SHS vous souhaite une excellente année 2023! Janvier 2023 Actualité du CST3D-SHS jc3dshs2022-Mise en ligne des communications Si vous avez manqué les rencontres du consortium 3D qui ont eu lieu les 14-15-16 ...
Consortium 3D SHS Team
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Principles of the 3D genome organization in malaria mosquitoes

, 2020
Poster "Principles of the 3D genome organization in malaria mosquitoes.
Varvara Lukyanchikova (8713636), Veniamin S. Fishman (3915167), Igor Sharakhov (5941565), Nariman R. Battulin (3915170), Alexander Tyapkin (8726452), Polina Belokopytova (8726454), Miroslav Nuriddinov (8726448)   +6 more
core   +1 more source

The CACTA transposon Bot1 played a major role in Brassica genome divergence and gene proliferation [PDF]

, 2008
We isolated and characterized a Brassica C genome-specific CACTA element, which was designated Bot1 (Brassica oleracea transposon 1). After analysing phylogenetic relationships, copy numbers and sequence similarity of Bot1 and Bot1 analogues in B ...
Joets, Johann, Moore, Jonathan D., Heslop-Harrison, J. (John), King , Graham J., Ryder, C. D., Heslop-Harrison, J. S., Joets, J., Bailey, John P., Moore, J., Ryder, Carol D., Bailey, J. P., Alix, K., Barker, G. C., King, G. J., Barker, Guy C., Alix, Karine   +15 more
core   +1 more source

CEACAM1 participation in breast cancer progression

Molecular Oncology, EarlyView.
In invasive breast cancer (BC), CEACAM1 shifts from an apical to a uniform membranous/cytoplasmic pattern, or is lost, as tumors dedifferentiate, inversely tracking the Ki‐67 proliferative index. In MCF‐7 cells, only CEACAM1‐4L suppresses proliferation, repressing cell cycle and growth factor genes.
Mykola Lyndin, Irina Kube‐Golovin, Anatolii Romaniuk, Gunther Wennemuth   +3 more
wiley   +1 more source

Cette visualisation en 3D de poumons endommagés par Covid-19 permet de mieux comprendre le danger

, 2020
" Une vidéo en 3D montre les dommages aux poumons d'une personne atteinte du Covid-19. Diffusée par le Dr. Keith Mortman, qui travaille à l'hôpital universitaire de George-Washington, aux Etats-Unis, la vidéo a été produite en partenariat avec Surgical ...
Consortium 3D SHS Team
core  

Pharmacological chromatin remodeling enhances response to estrogen therapy in ER+ breast cancer

Molecular Oncology, EarlyView.
Estrogen therapy elicits clinical benefit in ~ 30% of patients with endocrine‐resistant estrogen receptor (ER)‐positive breast cancer. Based on findings that ER transcriptional activation underlies response to estrogen therapy, we tested the effects of epigenetic dysregulation via pharmacological inhibition of histone deacetylases (HDACi).
Anneka L. Johnson Thomas, Barbara Karakyriakou, Patricia C. Muskus, Alyssa M. Roberts, Justin Rendleman, Alexa Warren, Hanxu Lu, Kimberly A. Birmingham, Malone K. Friedman, Abigail E. Goen, Huijuan Yang, Owen M. Wilkins, Fred W. Kolling, Eugene Demidenko, Julie M. Jorns, Brock C. Christensen, Todd W. Miller   +16 more
wiley   +1 more source

Deciphering histone mark-specific fine-scale chromatin organization at high resolution with Micro-C-ChIP

Nature Communications
The regulation of cell-type-specific transcription relies on complex 3D interactions between promoters and distal regulatory elements. Although Hi-C has advanced our understanding of genome architecture, its high sequencing demand limits use in large ...
Mariia Metelova, Maria Louisa Vigh, Nils Krietenstein   +2 more
doaj   +1 more source

Somatostatin receptor 4 (SSTR4) is a tumor suppressor in cutaneous and head & neck squamous cell carcinomas

Molecular Oncology, EarlyView.
This study identifies somatostatin receptor 4 (Sstr4) as a critical tumor suppressor against skin and head/neck cancers (HNSCC, cSCC, and BCC). The loss of Sstr4 removes a check on cell growth, causing hyperactivation of the MAPK‐ERK signaling pathway (↑).
Ali Taqvi, Tuan Khang Huynh, Adway Kadam, Zahra Kardan, Yue Yan, Amina Jamal Laham, Sampath Kumar Loganathan   +6 more
wiley   +1 more source

Dissecting the contribution of transposable elements to interphase chromosome structure

Genome Biology
Background Transposable elements (TEs) occupy nearly half of the human genome and play diverse biological roles. Despite their abundance, the extent to which TEs contribute to three-dimensional (3D) genome structure remains unclear.
Liyang Shi, Zhen Xiao, Xuemeng Zhou, Isaac A. Babarinde, Xiuling Fu, Gang Ma, Zhuoqi Huang, Li Sun, Jiangping He, Alexander Strunnikov, Andrew P. Hutchins   +10 more
doaj   +1 more source

jc3dshs 2022

, 2023
Les journées du Consortium 3D SHS ont eu lieu les 14-15-16 décembre dernier à Nantes au sein du laboratoire LS2N. Ces journées ont permis de communiquer sur les avancées au sein du Consortium, et plus généralement, au sein de la communauté scientifique ...
Consortium 3D SHS Team
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