Results 61 to 70 of about 2,629,967 (312)

3D Consortium: Creation, scientific use and archiving of 3D data for Humanities and Social Sciences

open access: yes, 2020
"Dariah annual Event 23- 24 mai 2018. The 3D Consortium, accredited in 2014 by Huma-Num, brings together eleven partners working in the field of archaeology and cultural heritage and who already have experience of using 3D technologies and producing 3D ...
Consortium 3D SHS Team
core  

Structure‐forward targeting of claudins with synthetic binders

open access: yesFEBS Letters, EarlyView.
Claudins form the paracellular barriers between epithelial and endothelial tissues at tight junctions and are targets for molecular binders with the goal of modulating barrier permeability. Claudin‐binding molecules are relevant in drug delivery or in altering claudin interactions with disease‐causing proteins.
Alex J. Vecchio
wiley   +1 more source

Open for connections: HiCAR reveals the interactions of accessible DNA

open access: yesCell Genomics, 2022
Hi-C is a powerful technology for exploring 3D genome organization on a genome-wide scale, yet it can be financially and computationally challenging. In a recent issue of Molecular Cell, Wei et al.1 introduce HiCAR, which simplifies Hi-C by targeting the
Benoit Moindrot, Daan Noordermeer
doaj   +1 more source

Discerning protein pools by selective staining with self‐labeling tags

open access: yesFEBS Letters, EarlyView.
Cell surface proteins have an intra‐ and extracellular pool. Combining genetic fusion to self‐labeling tags that can be addressed with small molecule fluorophores allows separating these pools. We highlight recent developments and techniques for state‐of‐the‐art interrogation of cell surface proteins in the complex tissue setting.
Kati Fischermanns, Johannes Broichhagen
wiley   +1 more source

Physical and data structure of 3D genome [PDF]

open access: yesScience Advances, 2019
New theoretical and experimental work suggests that 10-nm chromatin fiber is folded into tree-like domains in single cells.
Kai Huang   +9 more
openaire   +2 more sources

Pericentromeric heterochromatin is hierarchically organized and spatially contacts H3K9me2 islands in euchromatin.

open access: yesPLoS Genetics, 2020
Membraneless pericentromeric heterochromatin (PCH) domains play vital roles in chromosome dynamics and genome stability. However, our current understanding of 3D genome organization does not include PCH domains because of technical challenges associated ...
Yuh Chwen G Lee   +7 more
doaj   +1 more source

Conservatoire National de données 3D

open access: yes, 2020
" Le Conservatoire National des Données 3D SHS est un environnement de sauvegarde sécurisé pour les données 3D, soutenu par Huma-Num. .
Consortium 3D SHS Team
core  

Poste en photogrammétrie et modélisation 3D ( LabEx Archimede/CFEETK)

open access: yes, 2021
"Appel à candidatures du LabEx Archimede et de la Fondation Universitaire Hiérolexique (Université Paul Valéry – Montpellier 3) pour un CDD d’Ingénieur-e d’études en photogrammétrie et modélisation 3D auprès de l’USR 3172 du CNRS - CFEETK, à Karnak....
Consortium 3D SHS Team
core  

Pig genome sequence - analysis and publication strategy [PDF]

open access: yes, 2010
Background The pig genome is being sequenced and characterised under the auspices of the Swine Genome Sequencing Consortium. The sequencing strategy followed a hybrid approach combining hierarchical shotgun sequencing of BAC clones and whole genome ...
Fredholm, M.   +49 more
core   +1 more source

Nutrient/TOR signaling controls adipose mitochondrial transcription factor A (TFAM) to regulate organismal growth in Drosophila

open access: yesFEBS Letters, EarlyView.
Animals must match their growth rate to available nutrients. We show that in Drosophila larvae, the nutrient‐sensing TOR kinase controls growth by regulating levels of TFAM, a key regulator of mitochondrial function, in the adipose tissue. When nutrients are abundant, high TOR activity suppresses TFAM, lowering mitochondrial bioenergetic activity and ...
Shrivani Sriskanthadevan‐Pirahas   +4 more
wiley   +1 more source

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