Results 121 to 130 of about 235,191 (202)
Depot‐Specific Insulin Receptor Isoform Dynamics During Human Adipose‐Derived Stem Cell Adipogenesis
Obesity, Volume 34, Issue 11, Page 2124-2134, November 2026.Absolute quantification reveals depot‐specific insulin receptor (IR) isoform signatures in human adipose stem cells, with subcutaneous cells enriched in IRa and exhibiting greater adipogenic capacity and insulin responsiveness. The emergence of IR‐negative adipocytes highlights partially receptor‐independent pathways regulating human adipogenesis ...
Valentina Annamaria Genchi +10 more
wiley +1 more source
Insulin-stimulated glucose uptake in differentiated 3T3-L1 adipocytes.
, 2014 Differentiated 3T3-L1 adipocytes were treated with or without TNF-α (3 ng/ml) for 72 h in the presence or absence of Igf2 (400 ng/ml). *P≤0.05.
Yuji Arai (174599) +6 more
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Cancer Science, Volume 117, Issue 11, Page 3007-3021, November 2026.Adipocyte‐derived palmitic acid induces ZDHHC15‐mediated PPARγ S‐palmitoylation at Cys159, triggering its proteasomal degradation and promoting breast cancer malignancy with rosiglitazone resistance. Inhibition of PPARγ S‐palmitoylation by 2‐bromopalmitate suppresses breast cancer progression and synergistically enhances rosiglitazone efficacy ...
Geon Ho Moon +6 more
wiley +1 more source
Journal of Cellular and Molecular Medicine, Volume 30, Issue 21, November 2026.ABSTRACT Extracellular vesicles (EVs) are nanoscale, membrane‐enclosed particles that transfer proteins, nucleic acids, lipids, and other bioactive molecules between cells. Their cargo‐bearing capacity supports applications in drug delivery, regenerative medicine, and biomarker development, but ex vivo handling can alter vesicle recovery and cargo ...
Khadijeh Abbasi +7 more
wiley +1 more source
Schematic diagram for the effect of PPC on lipolysis and apoptosis in 3T3-L1 adipocytes.
, 2019 Schematic diagram for the effect of PPC on lipolysis and apoptosis in 3T3-L1 adipocytes.
Hyeong-Dong Kim (6564710) +11 more
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Seipin-A212P inhibits adipogenesis in 3T3-L1 cells.
, 2013 (A) A schematic diagram of the constructs used in generating the two stable 3T3-L1 cell lines expressing wild type Seipin (3T3-WT) or A212P mutant (3T3-A212P).
Kenneth Wee (387154) +6 more
core +1 more source
MicroRNA let-7 Regulates 3T3-L1 Adipogenesis
, 2009 Differentiation of 3T3-L1 cells into adipocytes involves a highly orchestrated series of events including clonal expansion, growth arrest, and terminal differentiation. The mechanisms coordinating these different steps are not yet fully understood.
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, 2012 (A) Dot plot of flow cytometry with selected pools. (B) Flow cytometry assay to monitor the pool enrichment for differentiated 3T3 adipocytes. (C) The slight shift of the respective pools to control 3T3-L1 preadipocyte was recovered by counter selection.
Ying Pu (161901) +6 more
core +1 more source
Adipolytic and adipogenic activities of SUB885C in 3T3-L1 adipocytes.
, 2012 (A) Glycerol release as the result of adipolysis in 3T3-L1 adipocytes after incubation with SUB885C (500× and 2500× diluted) and 20 µM isoproterenol dissolved in DMSO with 1% as final concentration. (B) Inhibition of adipose conversion in differentiating
Heng Wei (138563) +15 more
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Engineered 3T3-L1 adipocytes express and constitutively secrete leptin.
, 2016 3T3-L1 cells were stably transduced to overexpress Lep (3T3Lep) (A, B) Lep expression in non-differentiated preadipocytes (ND = non-differentiated) (A) and differentiated preadipocytes (D = differentiated) (B) is shown for 3T3-L1 (white bar) and 3T3Lep ...
Rumana Yasmeen (2602291) +7 more
core +1 more source