Results 101 to 110 of about 235,191 (202)

Ceramides, Particularly Those Containing Very‐Long‐Chain Saturated Fatty Acids, Are Independently Associated With the Triglyceride–Glucose Index in European Individuals With Type 2 Diabetes

Diabetes, Obesity and Metabolism, EarlyView.
ABSTRACT Aims The triglyceride–glucose (TyG) index is associated with insulin resistance and cardiovascular disease (CVD), but the underlying mechanisms remain unclear. As ceramides are implicated in both insulin resistance and CVD, we investigated the association between the TyG index and plasma ceramides in individuals with Type 2 diabetes (T2D ...
Laure Carpentier, Damien Denimal, Alexia Rouland, Jean‐Michel Petit, Jean Paul Pais de Barros, Laurence Duvillard, Benjamin Bouillet, Bruno Vergès   +7 more
wiley   +1 more source

TNFα impairs fatty acid oxidation in 3T3-L1 adipocytes.

, 2006
TNFα impairs fatty acid oxidation in 3T3-L1 ...
T Connor (13300326), Courtney Swinton (13065534), Gregory Collier (13049697), Nicky Konstantopoulos (13049994), Ken Walder (13099344), Severine Dubois (13049967)   +5 more
core  

Iodothyronine Interactions with the System L1 Amino Acid Exchanger in 3T3-L1 Adipocytes

, 2010
Thyroid hormones enter isolated white adipocytes largely by a System L1-type amino acid transporter en route to exerting genomic actions. Differentiated 3T3-L1 mouse adipocytes in culture express mRNA for LAT1 (the catalytic subunit of high-affinity ...
Lisa A. Roy, Mitchell, Fiona, Roy, Lisa A, Peter M. Taylor, Fiona E. Mitchell, Taylor, Peter M   +5 more
core   +1 more source

TGF‐β effects on adipogenesis of 3T3‐L1 cells differ in 2D and 3D cell culture conditions

FEBS Open Bio
The TGF‐β superfamily plays a pivotal role in the regulation of adipogenesis, but little is known about the potential differential role of the three isoforms of TGF‐β, TGF‐β‐1~3.
Araya Umetsu, Megumi Watanabe, Tatsuya Sato, Megumi Higashide, Nami Nishikiori, Masato Furuhashi, Hiroshi Ohguro   +6 more
doaj   +1 more source

Zaluzanin C Inhibits Differentiation of 3T3-L1 Preadipocytes into Mature Adipocytes

Journal of Obesity & Metabolic Syndrome, 2019
Background : An excess storage of body fat causes obesity. Since obesity increases risk of chronic diseases, it is important to inhibit excessive storage of fat. Zaluzanin C is a sesquiterpene lactone isolated from Ainsliaea acerifolia.
Sang Hee Kwak, Yoon Hee Kim
doaj   +1 more source

Preliminary Evidence for Adipocytokine Signals in Skeletal Muscle Glucose Uptake

Frontiers in Endocrinology, 2018
The cross talk between the adipose tissue and insulin target tissues is a key mechanism for obesity-associated insulin resistance. However, the precise role of the interaction between the skeletal muscle and adipose tissue for insulin signaling and ...
Akihiro Kudoh, Hiroaki Satoh, Hiroyuki Hirai, Tsuyoshi Watanabe, Michio Shimabukuro   +4 more
doaj   +1 more source

Tankyrase‐2 regulates adipocyte differentiation through AMPK/mTOR signaling

The FEBS Journal, EarlyView.
Tankyrase 2 (TNKS2), a PARP family member, underpins adipocyte differentiation. TNKS2 controls LKB1 protein level, and consequently, the activity of the mTOR/AMPK system and adipocyte differentiation through a layered process. Pharmacological inhibition of TNKS2 leaves other PARPs and DNA repair active and therefore represents a novel target in ...
Boglarka Rauch, Gyula Ujlaki, Szilard Poliska, Nakayi Murahwa, Patrik Kovacs, Aladar Pettko‐Szandtner, Karen Uray, Peter Bai   +7 more
wiley   +1 more source

Effects of CAde on 3T3-L1 pre-adipocytes cell viability.

, 2018
Effects of CAde on 3T3-L1 pre-adipocytes cell viability.
Michele Campitelli (4921576), Michele Longo (410577), Cecilia Nigro (401110), Eduardo Sommella (2214727), Gregory Alexander Raciti (671892), Pietro Campiglia (405663), Pietro Formisano (401115), Antonella Desiderio (4921570), Giacomo Pepe (4921573), Francesco Beguinot (221996), Francesca Fiory (401109), Rosa Spinelli (326152), Claudia Miele (221985)   +12 more
core   +1 more source

Innovations in Obesity Treatment: Beyond Adipose Tissue Dysfunction

Obesity Reviews, EarlyView.
Obesity drives chronic inflammation, insulin resistance, type 2 diabetes, and cancer development through adipocyte dysfunction. Addressing this multisystemic disorder requires integrated strategies beyond diet and exercise, such as thermogenesis activation via menthol or capsinoids and appetite control through GLP‐1/GIP agonists and neuromodulation to ...
Jesica Martínez‐Godfrey, Irene Pomares‐Bri, Paula de Juan‐Maciá, Mariló Olivares‐Vicente, Enrique Barrajón‐Catalán, Vicente Micol, Enrique Roche, María Herranz‐López   +7 more
wiley   +1 more source

Angiotensinogen gene expression in 3T3-L1 cells

, 1989
It has previously been established that angiotensinogen mRNA is present in brown and white adipose tissue of the rat. To determine whether angiotensinogen gene expression is present in adipocytes as compared with other cell elements, we have examined ...
T. W. Sturgill, M. J. Peach, J. A. Saye, K. R. Lynch, L. A. Cassis   +4 more
core   +1 more source