Results 81 to 90 of about 235,191 (202)
Knockdown of biglycan in 3T3-L1 adipocytes.
, 2013 A) Biglycan expression from 3T3-L1 mature adipocytes treated with siRNA against biglycan (“si biglycan”) or nontargeting siRNA (“scrambled”). Results are from RT-PCR and western blot for core biglycan protein (representative blot).
Meliza G. Ward (297567) +1 more
core +1 more source
Brd2 inhibits adipogenesis via the ERK1/2 signaling pathway in 3T3-L1 adipocytes.
PLoS ONE, 2013 Bromodomain-containing protein 2 (Brd2) is a nuclear serine/threonine kinase involved in transcriptional regulation. In 3T3-L1 adipocytes, Brd2 normally co-represses PPARγ (peroxisome proliferator-activated receptor gamma) and inhibits adipogenesis. Here,
Kun Zang +9 more
doaj +1 more source
Asian Pacific Journal of Tropical Biomedicine, 2016 Objective: To evaluate the anti-inflammatory property of both glycyrrhizic acid (GA) and glabridin in reducing inflammation to accelerate wound regeneration on 3T3-L1 and NIH-3T3 fibroblast cell lines. Methods: Cell proliferation and viability assay (MTT
Hong Yung Yip +2 more
doaj +1 more source
Smart Molecules, EarlyView.Inverse Diels‐Alder Cycloaddition Reaction was developed for ultrasensitive miR‐21 detection. Based on the enhanced Through‐Bond Energy Transfer and catalytic amplification, it shows a detection limit of 3.58 × 10−18 M and 100 aM–100 nM linear range. It enables high‐contrast cell/tissue imaging and distinguishes lung cancer patients in serum, promising
Yikun Li +10 more
wiley +1 more source
Ad36 ‘requires’ E4orf1 for glucose uptake in 3T3-L1 cells.
, 2013 3T3-L1 were transfected using lipofectamine with 100 pmol non-targeting (NT) siRNA or E4orf1 siRNA. E4siRNA transfected cells were immediately Mock infected or Ad36 infected (5 PFU/cell), and NT transfected cells were infected with Ad36 as positive ...
Rashmi Krishnapuram (302104) +5 more
core +1 more source
Depletion of AFF4 in hMSCs and 3T3-L1 cells.
, 2022 (A, B) Western blot and RT-qPCR analysis of AFF4 expression 48 h after AFF4 knockdown in hMSCs. (C) CCK8 assay of hMSCs proliferation. n = 6. (D, E) Western blot and RT-qPCR analysis of AFF4 expression 48 h after Aff4 knockdown in 3T3-L1 cells.
Weimin Lin (2117626) +11 more
core +1 more source
Is there a role for cannabidiol in obesity, metabolic syndrome and binge eating?
British Journal of Pharmacology, EarlyView.Cannabidiol (CBD) is one of the most abundant phytocannabinoids isolated from the Cannabis sativa plant. CBD is a lipophilic, non‐intoxicating substance that differently from Δ9‐tetrahydrocannabinol (Δ9‐THC) does not present the typical profile of a drug of abuse.
Luca Botticelli +7 more
wiley +1 more source
PDE4D and PDE3B orchestrate distinct cAMP microdomains in 3T3‐L1 adipocytes
British Journal of Pharmacology, EarlyView.Basal conditions: •Ins/PDE3B lowers cytoplasmic cAMP (cyt‐cAMP) without affecting plasma membrane cAMP (pm‐cAMP). •Insulin decreases lipid droplet cAMP (LD‐cAMP) independent of PDE3B. •FGF1/PDE4D modestly reduces both cyt‐ and pm‐cAMP, while PDE4D alone can modulate LD‐cAMP. ISO stimulation: •Ins/PDE3B has minimal impact on cyt‐cAMP.
Johannes Krier +9 more
wiley +1 more source
INFLUENCE OF 5,7-DIMETHOXY COUMARIN ON ADIPOGENESIS IN HIGH GLUCOSE INDUCED INSULIN RESISTANT 3T3-L1 ADIPOCYTES [PDF]
Insulin resistance in adipocytes disrupts whole-body metabolic homeostasis contributing to various complications. This study investigates the adipogenic potential of 5,7-dimethoxy Coumarin (5,7-DMC) in high glucose-induced insulin resistance in 3T3-L1 ...
J. JOHN ROBERT +2 more
core +1 more source
Molecules, 2018 Conflicting results for morusin activity during adipogenic differentiation are reported in 3T3-L1 adipocytes and cancer cells. To elucidate the influence of morusin on fat metabolism, their anti-obesity effects and molecular mechanism were investigated ...
Mi Rim Lee +10 more
doaj +1 more source