Results 91 to 100 of about 235,191 (202)
Impact of incretin analogues on lipid and lipoprotein metabolism in obesity and diabetes
British Journal of Pharmacology, EarlyView.Abstract Incretin‐based therapies have gained momentum as a key strategy for reducing cardiovascular risk in individuals with obesity and/or type 2 diabetes (T2D). It remains unclear whether the cardiovascular benefits reflect a direct reduction in atherogenic lipoproteins—namely, low‐density lipoproteins (LDL), very low‐density lipoproteins (VLDL) and
Andrea Baragetti, Giuseppe Danilo Norata
wiley +1 more source
A-FABP-PTEN/AKT Regulates Insulin Resistance in Preadipocyte Cell 3T3-L1 Cells
Diabetes, Metabolic Syndrome and Obesity, 2021 Rensiqin Wu,1 Hui Wang,1 Jian Huangfu,1 Rui Xiao2 1Department of Endocrinology, The Affiliated Hospital of Inner Mongolia Medical University, Hohhot, 010000, Inner Mongolia, People’s Republic of China; 2Key Laboratory of Molecular Pathology, Inner ...
Wu R, Wang H, Huangfu J, Xiao R
doaj
British Journal of Pharmacology, EarlyView.Obesity is a chronic, relapsing, multisystem disease in which cardiometabolic risk arises from excess adiposity and progressive dysfunction of peripheral organs, ultimately disrupting endocrine and metabolic crosstalk among tissues. Within this network, sulphur‐based biology, centred on hydrogen sulphide and related reactive sulphur species, has ...
Martina Smimmo +4 more
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Representative immunoblots of MAPK phosphorylation in 3T3-L1 preadipocytes and mature adipocytes.
, 2014 3T3-L1 cells were treated with LPS (10 ng/ml); Palmitic acid (0.5 mM); Myristic acid (0.5 mM); and Oleic acid (0.5 mM) for 0, 1 and 2 h. Phosphorylation levels of p38 (Thr180/Tyr182) relative to total p38; and phosphor-JNK (Thr183/Tyr185) relative to ...
Aimee L. Dordevic (575119) +2 more
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British Journal of Pharmacology, EarlyView.Abstract Background and Purpose The nuclear receptor NR4A1 is a critical node in transcriptional circuits for metabolic adaptation, yet its role in adipocyte progenitor (AP) fate and proliferation is unclear. We sought to define how NR4A1 governs early adipogenesis and adipose tissue plasticity.
Wanning Qiao +13 more
wiley +1 more source
TNFÁ impairs mitochondrial metabolism in 3T3-L1 adipocytes
, 2006 TNFÁ impairs mitochondrial metabolism in 3T3-L1 ...
T Connor (13300326) +5 more
core
Representative immunoblots of NF-κB activation in 3T3-L1 preadipocytes and mature adipocytes.
, 2014 3T3-L1 cells were treated with LPS (10 ng/ml); Palmitic acid (0.5 mM); Myristic acid (0.5 mM); and Oleic acid (0.5 mM) for 0, 1 and 2 h. Phosphorylation levels of p65 (Ser536) relative to total p65; and total levels of IκBα relative to α-tubulin were ...
Aimee L. Dordevic (575119) +2 more
core +1 more source
AdipocyteVolume-activated chloride current (VACC), the most common and abundant anion current in organisms, is involved in various physiological and pathological processes. However, its expression and characteristics in preadipocytes remain unclear.
Hua Guan +9 more
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Anti-adipocyte Differentiation Activity and Chemical Composition of Essential Oil from
Natural Product Communications, 2016 Artemisia annua L. essential oil (AAEO) has diverse properties including antibacterial, antioxidant, antinociceptive, and antimicrobial activities. However, the effect of AAEO on obesity remains to be investigated.
Dae Il Hwang +6 more
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Frontiers in Physiology, 2019 ObjectiveGhrelin is a 28-amino-acid peptide that regulates energy hemostasis, glucose and lipid metabolism. We aimed to explore the effects of ghrelin on the proliferation and differentiation of 3T3-L1 and human primary preadipocytes.Methods3-(4,5 ...
Hui Miao +5 more
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