Results 61 to 70 of about 235,191 (202)
3T3-L1 adipocyte differentiation.
(A) Phase contrast images of 3T3-L1 cells from induction (day 0) to ten days post-induction. Cells initially display a fibroblast phenotype. Over the course of differentiation, cell morphology changes and cells accumulate lipid droplets internally.
Nicholas Marze (841739) +2 more
core +1 more source
TG-interacting factor is required for the differentiation of preadipocytes
The accumulation of visceral adipose tissue is closely associated with insulin resistance and metabolic syndrome. Therefore, it is important to identify genes that are required for adipocyte differentiation.
Takahiro Horie +10 more
doaj +1 more source
Recent Advances in Top‐Down Proteomics for Single‐Cell Research
ABSTRACT Individual cells have distinctive molecular characteristics, including biologically relevant proteoforms. Although single‐cell (SC) molecular omics offer unprecedented insights into cellular heterogeneity and function, the characterization of proteoforms in SCs remains an uncharted territory.
Jake A. Melby, Pei Su, Fabio P. Gomes
wiley +1 more source
Knocking down Stard3 decreases adipogenesis with decreased mitochondrial ROS in 3T3-L1 cells [PDF]
Start domain-containing protein 3 (Stard3) plays roles in intracellular cholesterol distribution, however, the role of Stard3 in the adipogenesis of 3T3-L1 preadipocytes remains unclear.
Ruan, XZ +4 more
core +1 more source
Background Increased consumption of omega-3 (ω-3) fatty acids found in cold-water fish and fish oil has been reported to protect against obesity. A potential mechanism may be through reduction in adipocyte differentiation. Stearidonic acid (SDA), a plant-
Yueru Li +9 more
doaj +1 more source
Possible involvement of Opa-interacting protein 5 in adipose proliferation and obesity. [PDF]
Obesity is an epidemic matter increasing risk for cardiovascular diseases and metabolic disorders such as type 2 diabetes. We recently examined the association between visceral fat adiposity and gene expression profile of peripheral blood cells in human ...
Kana Inoue +11 more
doaj +1 more source
Navigating the Complexity: A Comprehensive Review of GSK‐3 Inhibition in Regenerative Medicine
ABSTRACT Glycogen synthase kinase‐3 (GSK‐3) is a central regulator of numerous cellular signaling pathways, with critical roles in metabolism, proliferation, differentiation, and tissue regeneration. This review explores the multifaceted effects of pharmacological GSK‐3 inhibition across multiple body districts, focusing on its highly context‐dependent
Davide Schiroli +5 more
wiley +1 more source
Expression of VPAC/PAC receptors in 3T3-L1 cells during differentiation of 3T3-L1 cells.
A. qPCR analysis of the mRNA expression of VPAC/PAC receptors in 3T3-L1 two days post-confluent cells (day 0) and during differentiation till day 9.
Elodie Courtequisse (455776) +6 more
core +1 more source
Effect of distinct pharmacological compounds on viability of 3T3-L1 cells in culture.
3T3-L1 preadipocytes (2 x 105 cells/well) were incubated with DMSO (TIF)
Carlos DeOcesano-Pereira (5459984) +5 more
core +1 more source
Epigenetic regulation of adipocyte differentiation by a Rho guanine nucleotide exchange factor, WGEF. [PDF]
Epigenetic regulation, including DNA methylation, plays an important role in several differentiation processes and possibly in adipocyte differentiation.
Takuro Horii +3 more
doaj +1 more source

