Results 41 to 50 of about 58,354 (259)

Characterizing 3T3-L1 MBX Adipocyte Cell Differentiation Maintained with Fatty Acids as an In Vitro Model to Study the Effects of Obesity

Life, 2023
The increasing prevalence of obesity has prompted intensive research into understanding its role in pathogenesis and designing appropriate treatments. To determine the signals generated from the interaction of fat cells with a target organ, a reliable ...
Noshin Mubtasim, Lauren Gollahon
doaj   +1 more source

Impaired release of Vitamin D in dysfunctional adipose tissue: New cues on Vitamin D supplementation in obesity [PDF]

, 2017
Context: Vitamin D accumulates in adipose tissue (AT) and vitamin D deficiency is frequent in obesity. Objective: We hypothesize that trafficking of vitamin D is altered in dysfunctional AT.
Azzena, Bruno, DE FILIPPIS, Vincenzo, DE TONI, Luca, DI NISIO, Andrea, Foresta, Carlo, Opocher, Giuseppe, Plebani, Mario, Rocca, MARIA SANTA, Sabovic, Iva, Vettor, Roberto   +9 more
core   +1 more source

Phosphatidylcholine induces apoptosis of 3T3-L1 adipocytes [PDF]

Journal of Biomedical Science, 2011
Abstract Background Phosphatidylcholine (PPC) formulation is used for lipolytic injection, even though its mechanism of action is not well understood. Methods The viability of 3T3-L1 pre-adipocytes and differentiated 3T3-L1 cells was measured after treatment of PPC alone ...
Li Hailan, Lee Jong-Hyuk, Kim Su Yeon, Yun Hye-Young, Baek Kwang Jin, Kwon Nyoun Soo, Yoon Yoosik, Jeong Ji Hoon, Kim Dong-Seok   +8 more
openaire   +3 more sources

Adipocytes cause leukemia cell resistance to daunorubicin via oxidative stress response. [PDF]

, 2016
Adipocytes promote cancer progression and impair treatment, and have been shown to protect acute lymphoblastic leukemia (ALL) cells from chemotherapies. Here we investigate whether this protection is mediated by changes in oxidative stress.
Behan, James W, Heisterkamp, Nora, Ji, Lingyun, Mittelman, Steven D, Parmentier, Jean-Hugues, Sheng, Xia, Tucci, Jonathan   +6 more
core   +1 more source

Cathelicidin suppresses lipid accumulation and hepatic steatosis by inhibition of the CD36 receptor. [PDF]

, 2016
Background and objectivesObesity is a global epidemic which increases the risk of the metabolic syndrome. Cathelicidin (LL-37 and mCRAMP) is an antimicrobial peptide with an unknown role in obesity.
Bakirtzi, K, Cheng, M, Fisseha, E, Fleshner, P, Gallo, RL, Hing, TC, Ho, S, Hoang-Ngoc Tran, D, Hoang-Yen Tran, D, Karagiannides, I, Koon, HW, Law, I, Lee, EC, Lee, JE, Li, Z, Mattai, SA, McGovern, DPB, Ortiz, C, Robbins, L, Sallam, T, Shieh, C, Shih, DQ, Sideri, A, Su, B, Targan, SR, Vu, M   +25 more
core   +1 more source

Centipede grass exerts anti-adipogenic activity through inhibition of C/EBPβ, C/EBPα, and PPARγ expression and the AKT signaling pathway in 3T3-L1 adipocytes

BMC Complementary and Alternative Medicine, 2012
Background Centipede grass (CG) originates from China and South America and is reported to contain several C-glycosyl flavones and phenolic constituents, including maysin and luteolin derivatives.
Park Hyoung Joon, Chung Byung Yeoup, Lee Min-Kwon, Song Yuno, Lee Seung Sik, Chu Gyo Moon, Kang Suk-Nam, Song Young Min, Kim Gon-Sup, Cho Jae-Hyeon   +9 more
doaj   +1 more source

Vaspin promotes 3T3-L1 preadipocyte differentiation [PDF]

Experimental Biology and Medicine, 2015
Vaspin, a novel adipocyte factor secreted from visceral adipose tissues, is associated with obesity and insulin resistance and can regulate glucose and lipid metabolism, increase insulin sensitivity, and suppress inflammation; however, the underlying mechanisms remain unknown.
Ping, Liu, Guoliang, Li, Jine, Wu, Xin, Zhou, Liping, Wang, Wenqi, Han, Ying, Lv, Chaofeng, Sun   +7 more
openaire   +2 more sources

Investigating the role of EPA and DHA on cellular oxidative stress; profiling antidiabetic and antihypertensive potential

Journal of Pharmacy and Bioallied Sciences, 2022
Background: Polyunsaturated fatty acids (PUFAs) remain part of the diet and are essential for growth and development. Furthermore, omega − 3 fatty acids boost various cardiovascular disease risk factors as well as lower blood pressure and cholesterol ...
Fahad K Aldhafiri
doaj   +1 more source

GALNT2 as a novel modulator of adipogenesis and adipocyte insulin signaling [PDF]

, 2019
Background/objectives: A better understanding of adipose tissue biology is crucial to tackle insulin resistance and eventually coronary heart disease and diabetes, leading causes of morbidity and mortality worldwide.
Antonucci, A., De Bonis, Maria Caterina, Di Paola, R., Mangiacotti, D., Marucci, A., Scarale, M. G., Trischitta, V.   +6 more
core   +1 more source

Glucocorticoid Receptor and Adipocyte Biology. [PDF]

, 2018
Glucocorticoids are steroid hormones that play a key role in metabolic adaptations during stress, such as fasting and starvation, in order to maintain plasma glucose levels.
Harris, Charles A, Lee, Rebecca A, Wang, Jen-Chywan   +2 more
core   +2 more sources