Results 41 to 50 of about 235,191 (202)
Characteristics of 3T3-L1 cells with Brd2 knockdown.
, 2013 3T3-L1 cells were transfected with Brd2 shRNA (SiBrd2) or scramble shRNA (SiC) plasmids respectively. (A) Adipogenic differentiation of 3T3-L1 adipocytes from pre-adipocytes and Oil Red O staining on day 4 of treatment reveals lipids in cells that have ...
Jingyu Wang (292122) +9 more
core +1 more source
Journal of Lipid Research, 1998 Synthesis and accumulation of the recently identified prostaglandin F2α receptor regulatory protein (FPRP) was found to correlate closely with lipid droplet accumulation by 3T3-L1 preadipose cells.
D.J. Orlicky +3 more
doaj +1 more source
Advanced Science, EarlyView.Guided by spatial transcriptomics and clinical validation, a threaded microneedle platform enables precise layer‐specific delivery across the dermis and subcutaneous tissue. By addressing distinct pathogenic remodeling in different skin layers, this strategy coordinates compartment‐specific intervention, restores tissue architecture, and offers a ...
Fangzhou Xie +14 more
wiley +1 more source
, 2019 To investigate a comprehensive transcriptome information of adipogenesis, we assessed global changes in the transcriptional events during 3T3-L1 adipogenesis by RNA-Seq.
Chengping Li (6113939) +5 more
core +1 more source
The role of cyclic nucleotide phosphodiesterases in the regulation of adipocyte lipolysis
Journal of Lipid Research, 2005 This study assessed the effects of selective inhibitors of 3′,5′-cyclic nucleotide phosphodiesterases (PDEs) on adipocyte lipolysis. IC224, a selective inhibitor of type 1 phosphodiesterase (PDE1), suppressed lipolysis in murine 3T3-L1 adipocytes (69.6 ±
Peter B. Snyder +4 more
doaj +1 more source
Insulin-stimulated lipid accumulation is inhibited by ROS-scavenging chemicals, but not by the Drp1 inhibitor Mdivi-1. [PDF]
PLoS ONE, 2017 Adipocyte differentiation is regulated by intracellular reactive oxygen species (ROS) generation and mitochondrial fission and fusion processes. However, the correlation between intracellular ROS generation and mitochondrial remodeling during adipocyte ...
Jung-Hak Kim +5 more
doaj +1 more source
Advanced Science, EarlyView.A bioactive self‐delivering SNAP‐TAC platform responds to tumor‐associated cathepsin B and glutathione, enabling in situ bioorthogonal synthesis of a BRD4‐degrading proteolysis‐targeting chimera within the tumor microenvironment. The resulting BRD4 degradation and PD‐L1 downregulation synergize with photodynamic therapy‐induced immunogenic cell death ...
Shiqin Jian +14 more
wiley +1 more source
Perturbed MDI-induced 3T3-L1 gene expression data by RNA-seq.
, 2022 Perturbed MDI-induced 3T3-L1 gene expression data by RNA-seq.
Deok Ryong Kim (3041154) +6 more
core +1 more source
Advanced Science, EarlyView.Bioengineered stroma‐camouflaged nanovesicles (AM@UIO‐BMS/DOX) convert the immunosuppressive tumor niche into an immunoresponsive milieu by disrupting the IDO1/CD276 circuit. Anti‐CD276 membrane camouflage guides tumor accumulation and deep penetration, enabling controlled co‐delivery of DOX and the IDO1 inhibitor BMS‐986205.
Ziqi Zhang +11 more
wiley +1 more source
HDL stimulates glucose uptake in 3T3-L1 adipocytes.
, 2013 3T3-L1 adipocytes were incubated with vehicle or stimulators for 30 min before being incubated for another 30 min with 1-[3H]-2- deoxyglucose. (A) 3T3-L1 adipocytes were incubated with vehicle (BSA), HDL (50 µg protein/ml), insulin (100 nmol/L) or ...
Lina Wang (44695) +8 more
core +1 more source